286 related articles for article (PubMed ID: 16947002)
1. HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway.
Laezza C; Mazziotti G; Fiorentino L; Gazzerro P; Portella G; Gerbasio D; Carella C; Matarese G; Bifulco M
J Mol Med (Berl); 2006 Nov; 84(11):967-73. PubMed ID: 16947002
[TBL] [Abstract][Full Text] [Related]
2. Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2.
Cho KJ; Hill MM; Chigurupati S; Du G; Parton RG; Hancock JF
Mol Cell Biol; 2011 Mar; 31(6):1110-20. PubMed ID: 21245384
[TBL] [Abstract][Full Text] [Related]
3. Enhanced expression of transforming growth factor beta1 in rat thyroid hyperplasia is thyrotropin induced and time dependent.
Morosini PP; Taccaliti A; Arnaldi G; Simonella G; Petrelli MD; Mancini V; Montironi R; Scarpelli M; Diamanti L; Mantero F
Eur J Endocrinol; 1996 Mar; 134(3):373-8. PubMed ID: 8616538
[TBL] [Abstract][Full Text] [Related]
4. Lovastatin blocks basic fibroblast growth factor-induced mitogen-activated protein kinase signaling in coronary smooth muscle cells via phosphatase inhibition.
Skaletz-Rorowski A; Müller JG; Kroke A; Waltenberger J; Pulawski E; Pinkernell K; Breithardt G
Eur J Cell Biol; 2001 Mar; 80(3):207-12. PubMed ID: 11322384
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of Ras farnesylation by lovastatin leads to downregulation of proliferation and migration in primary cultured human glioblastoma cells.
Bouterfa HL; Sattelmeyer V; Czub S; Vordermark D; Roosen K; Tonn JC
Anticancer Res; 2000; 20(4):2761-71. PubMed ID: 10953355
[TBL] [Abstract][Full Text] [Related]
6. Effect of vitamin E on follicular cell proliferation and expression of apoptosis-associated factors in rats with 6-N-propyl-2-thiouracil-induced goitrogenesis.
Oner J; Kükner A; Oner H; Ozan E; Yekeler H
Folia Histochem Cytobiol; 2003; 41(4):213-7. PubMed ID: 14677760
[TBL] [Abstract][Full Text] [Related]
7. Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming growth factor-beta1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells.
Song CY; Kim BC; Lee HS
Transl Res; 2008 Jan; 151(1):27-35. PubMed ID: 18061125
[TBL] [Abstract][Full Text] [Related]
8. Lovastatin prevents angiotensin II-induced cardiac hypertrophy in cultured neonatal rat heart cells.
Oi S; Haneda T; Osaki J; Kashiwagi Y; Nakamura Y; Kawabe J; Kikuchi K
Eur J Pharmacol; 1999 Jul; 376(1-2):139-48. PubMed ID: 10440099
[TBL] [Abstract][Full Text] [Related]
9. Oxidative stress: a required condition for thyroid cell proliferation.
Poncin S; Van Eeckoudt S; Humblet K; Colin IM; Gérard AC
Am J Pathol; 2010 Mar; 176(3):1355-63. PubMed ID: 20093493
[TBL] [Abstract][Full Text] [Related]
10. Prenyltransferase inhibitors induce apoptosis in proliferating thyroid cells through a p53-independent CrmA-sensitive, and caspase-3-like protease-dependent mechanism.
Vitale M; Di Matola T; Rossi G; Laezza C; Fenzi G; Bifulco M
Endocrinology; 1999 Feb; 140(2):698-704. PubMed ID: 9927296
[TBL] [Abstract][Full Text] [Related]
11. HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.
Chen JC; Huang KC; Lin WW
Cell Signal; 2006 Jan; 18(1):32-9. PubMed ID: 16214041
[TBL] [Abstract][Full Text] [Related]
12. Xiao-Luo-Wan treats propylthiouracil-induced goiter with hypothyroidism in rats through the PI3K-AKT/RAS pathways based on UPLC/MS and network pharmacology.
Dong S; Liu Q; Jiang M; Ma Q; Huang Q; Liu T; Li Y; Ni L; Shi Y
J Ethnopharmacol; 2022 May; 289():115045. PubMed ID: 35101570
[TBL] [Abstract][Full Text] [Related]
13. Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis.
Wu J; Wong WW; Khosravi F; Minden MD; Penn LZ
Cancer Res; 2004 Sep; 64(18):6461-8. PubMed ID: 15374955
[TBL] [Abstract][Full Text] [Related]
14. Lovastatin is a potent inhibitor of meningioma cell proliferation: evidence for inhibition of a mitogen associated protein kinase.
Johnson MD; Woodard A; Okediji EJ; Toms SA; Allen GS
J Neurooncol; 2002 Jan; 56(2):133-42. PubMed ID: 11995814
[TBL] [Abstract][Full Text] [Related]
15. Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin.
Ruiz-DeDiego I; Fasano S; Solís O; Garcia-Montes JR; Brea J; Loza MI; Brambilla R; Moratalla R
Sci Rep; 2018 Oct; 8(1):15381. PubMed ID: 30337665
[TBL] [Abstract][Full Text] [Related]
16. MEK and ERK activation in ras-disabled RBL-2H3 mast cells and novel roles for geranylgeranylated and farnesylated proteins in Fc epsilonRI-mediated signaling.
Graham TE; Pfeiffer JR; Lee RJ; Kusewitt DF; Martinez AM; Foutz T; Wilson BS; Oliver JM
J Immunol; 1998 Dec; 161(12):6733-44. PubMed ID: 9862703
[TBL] [Abstract][Full Text] [Related]
17. [Time-effect study of propylthiouracil-induced thyroid gland hyperplasia].
Wang Y; Zhang S; Cheng W; Zeng T
Wei Sheng Yan Jiu; 2009 Jan; 38(1):15-9. PubMed ID: 19267066
[TBL] [Abstract][Full Text] [Related]
18. Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo.
McAnally JA; Gupta J; Sodhani S; Bravo L; Mo H
Exp Biol Med (Maywood); 2007 Apr; 232(4):523-31. PubMed ID: 17392488
[TBL] [Abstract][Full Text] [Related]
19. Differentiation and apoptosis induction by lovastatin and γ-tocotrienol in HL-60 cells via Ras/ERK/NF-κB and Ras/Akt/NF-κB signaling dependent down-regulation of glyoxalase 1 and HMG-CoA reductase.
Chen CC; Liu TY; Huang SP; Ho CT; Huang TC
Cell Signal; 2015 Nov; 27(11):2182-90. PubMed ID: 26208883
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells.
Bifulco M; Laezza C; Aloj SM
Biochimie; 1999 Apr; 81(4):287-90. PubMed ID: 10401660
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]