BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 16948470)

  • 1. Quantitative structure-activity relationship studies on matrix metalloproteinase inhibitors: hydroxamic acid analogs.
    Gupta SP; Kumaran S
    Med Chem; 2006 May; 2(3):243-50. PubMed ID: 16948470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A quantitative structure-activity relationship study on matrix metalloproteinase inhibitors: piperidine sulfonamide aryl hydroxamic acid analogs.
    Kumaran S; Gupta SP
    J Enzyme Inhib Med Chem; 2007 Feb; 22(1):23-7. PubMed ID: 17373543
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A quantitative structure-activity relationship study on some novel series of hydroxamic acid analogs acting as matrix metalloproteinase inhibitors.
    Kumaran S; Gupta SP
    Med Chem; 2007 Mar; 3(2):167-73. PubMed ID: 17348854
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.
    Levin JI; Gu Y; Nelson FC; Zask A; DiJoseph JF; Sharr MA; Sung A; Jin G; Cowling R; Chanda P; Cosmi S; Hsiao CL; Edris W; Wilhelm J; Killar LM; Skotnicki JS
    Bioorg Med Chem Lett; 2001 Jan; 11(2):239-42. PubMed ID: 11206468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MMPs inhibitors: new succinylhydroxamates with selective inhibition of MMP-2 over MMP-3.
    Marcq V; Mirand C; Decarme M; Emonard H; Hornebeck W
    Bioorg Med Chem Lett; 2003 Sep; 13(17):2843-6. PubMed ID: 14611841
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A quantitative structure-activity relationship study on some matrix metalloproteinase and collagenase inhibitors.
    Kumar D; Gupta SP
    Bioorg Med Chem; 2003 Feb; 11(3):421-6. PubMed ID: 12517437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The discovery of anthranilic acid-based MMP inhibitors. Part 1: SAR of the 3-position.
    Levin JI; Du MT; DiJoseph JF; Killar LM; Sung A; Walter T; Sharr MA; Roth CE; Moy FJ; Powers R; Jin G; Cowling R; Skotnicki JS
    Bioorg Med Chem Lett; 2001 Jan; 11(2):235-8. PubMed ID: 11206467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Malonyl alpha-mercaptoketones and alpha-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors.
    Campbell DA; Xiao XY; Harris D; Ida S; Mortezaei R; Ngu K; Shi L; Tien D; Wang Y; Navre M; Patel DV; Sharr MA; DiJoseph JF; Killar LM; Leone CL; Levin JI; Skotnicki JS
    Bioorg Med Chem Lett; 1998 May; 8(10):1157-62. PubMed ID: 9871727
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Picking the S1, S1' and S2' pockets of matrix metalloproteinases. A niche for potent acyclic sulfonamide inhibitors.
    Hanessian S; Bouzbouz S; Boudon A; Tucker GC; Peyroulan D
    Bioorg Med Chem Lett; 1999 Jun; 9(12):1691-6. PubMed ID: 10397503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13.
    Tommasi RA; Weiler S; McQuire LW; Rogel O; Chambers M; Clark K; Doughty J; Fang J; Ganu V; Grob J; Goldberg R; Goldstein R; Lavoie S; Kulathila R; Macchia W; Melton R; Springer C; Walker M; Zhang J; Zhu L; Shultz M
    Bioorg Med Chem Lett; 2011 Nov; 21(21):6440-5. PubMed ID: 21937229
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases.
    Pikul S; McDow Dunham KL; Almstead NG; De B; Natchus MG; Anastasio MV; McPhail SJ; Snider CE; Taiwo YO; Chen L; Dunaway CM; Gu F; Mieling GE
    J Med Chem; 1999 Jan; 42(1):87-94. PubMed ID: 9888835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The design, synthesis, and structure-activity relationships of a series of macrocyclic MMP inhibitors.
    Steinman DH; Curtin ML; Garland RB; Davidsen SK; Heyman HR; Holms JH; Albert DH; Magoc TJ; Nagy IB; Marcotte PA; Li J; Morgan DW; Hutchins C; Summers JB
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2087-92. PubMed ID: 9873491
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based design and synthesis of a series of hydroxamic acids with a quaternary-hydroxy group in P1 as inhibitors of matrix metalloproteinases.
    Jacobson IC; Reddy PG; Wasserman ZR; Hardman KD; Covington MB; Arner EC; Copeland RA; Decicco CP; Magolda RL
    Bioorg Med Chem Lett; 1998 Apr; 8(7):837-42. PubMed ID: 9871551
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selectivity of inhibition of matrix metalloproteases MMP-3 and MMP-2 by succinyl hydroxamates and their carboxylic acid analogues is dependent on P3' group chirality.
    Fray MJ; Burslem MF; Dickinson RP
    Bioorg Med Chem Lett; 2001 Feb; 11(4):567-70. PubMed ID: 11229773
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydroxamate derivatives of substrate-analogous peptides containing aminomalonic acid are potent inhibitors of matrix metalloproteinases.
    Krumme D; Wenzel H; Tschesche H
    FEBS Lett; 1998 Oct; 436(2):209-12. PubMed ID: 9781680
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel series of highly selective inhibitors of MMP-3.
    Whitlock GA; Dack KN; Dickinson RP; Lewis ML
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6750-3. PubMed ID: 18029177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (stromelysin-1).
    Fray MJ; Dickinson RP
    Bioorg Med Chem Lett; 2001 Feb; 11(4):571-4. PubMed ID: 11229774
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A comparative QSAR study on carbonic anhydrase and matrix metalloproteinase inhibition by sulfonylated amino acid hydroxamates.
    Gupta SP; Maheswaran V; Pande V; Kumar D
    J Enzyme Inhib Med Chem; 2003 Feb; 18(1):7-13. PubMed ID: 12751815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Broad spectrum matrix metalloproteinase inhibitors: an examination of succinamide hydroxamate inhibitors with P1 C alpha gem-disubstitution.
    Curtin ML; Garland RB; Davidsen SK; Marcotte PA; Albert DH; Magoc TJ; Hutchins C
    Bioorg Med Chem Lett; 1998 Jun; 8(12):1443-8. PubMed ID: 9873367
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13.
    Noe MC; Natarajan V; Snow SL; Mitchell PG; Lopresti-Morrow L; Reeves LM; Yocum SA; Carty TJ; Barberia JA; Sweeney FJ; Liras JL; Vaughn M; Hardink JR; Hawkins JM; Tokar C
    Bioorg Med Chem Lett; 2005 Jun; 15(11):2808-11. PubMed ID: 15911259
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.