BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 16951159)

  • 21. TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly phosphorylated, and indicates poor prognosis in node-negative breast cancer.
    Helms MW; Kemming D; Contag CH; Pospisil H; Bartkowiak K; Wang A; Chang SY; Buerger H; Brandt BH
    Cancer Res; 2009 Jun; 69(12):5049-56. PubMed ID: 19491269
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation.
    Huang H; Regan KM; Wang F; Wang D; Smith DI; van Deursen JM; Tindall DJ
    Proc Natl Acad Sci U S A; 2005 Feb; 102(5):1649-54. PubMed ID: 15668399
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCFSkp2 ubiquitin ligase.
    Tokarz S; Berset C; La Rue J; Friedman K; Nakayama K; Nakayama K; Zhang DE; Lanker S
    J Biol Chem; 2004 Nov; 279(45):46424-30. PubMed ID: 15342634
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1.
    Jonason JH; Gavrilova N; Wu M; Zhang H; Sun H
    Cell Cycle; 2007 Apr; 6(8):951-61. PubMed ID: 17438373
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer.
    Hershko DD
    Cancer; 2008 Apr; 112(7):1415-24. PubMed ID: 18260093
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase.
    Tamamori-Adachi M; Takagi H; Hashimoto K; Goto K; Hidaka T; Koshimizu U; Yamada K; Goto I; Maejima Y; Isobe M; Nakayama KI; Inomata N; Kitajima S
    Cardiovasc Res; 2008 Nov; 80(2):181-90. PubMed ID: 18596061
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Growth inhibition of a tongue squamous cell carcinoma cell line (Tca8113) in vitro and in vivo via siRNA-mediated down-regulation of skp2.
    Fang L; Hu Q; Hua Z; Li S; Dong W
    Int J Oral Maxillofac Surg; 2008 Sep; 37(9):847-52. PubMed ID: 18620845
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1.
    Park TJ; Kim JY; Park SH; Kim HS; Lim IK
    Exp Cell Res; 2009 Nov; 315(18):3152-62. PubMed ID: 19615363
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Chimeric molecules to target proteins for ubiquitination and degradation.
    Sakamoto KM
    Methods Enzymol; 2005; 399():833-47. PubMed ID: 16338398
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.
    Wang W; Nacusi L; Sheaff RJ; Liu X
    Biochemistry; 2005 Nov; 44(44):14553-64. PubMed ID: 16262255
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.
    Kamura T; Hara T; Kotoshiba S; Yada M; Ishida N; Imaki H; Hatakeyama S; Nakayama K; Nakayama KI
    Proc Natl Acad Sci U S A; 2003 Sep; 100(18):10231-6. PubMed ID: 12925736
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT.
    Ganiatsas S; Dow R; Thompson A; Schulman B; Germain D
    Oncogene; 2001 Jun; 20(28):3641-50. PubMed ID: 11439327
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Skp1 stabilizes the conformation of F-box proteins.
    Yoshida Y; Murakami A; Tanaka K
    Biochem Biophys Res Commun; 2011 Jun; 410(1):24-8. PubMed ID: 21640084
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Evidence for cytosolic p27(Kip1) ubiquitylation and degradation during adipocyte hyperplasia.
    Auld CA; Morrison RF
    Obesity (Silver Spring); 2006 Dec; 14(12):2136-44. PubMed ID: 17189539
    [TBL] [Abstract][Full Text] [Related]  

  • 35. MDA-7/IL-24, a novel tumor suppressor/cytokine is ubiquitinated and regulated by the ubiquitin-proteasome system, and inhibition of MDA-7/IL-24 degradation enhances the antitumor activity.
    Gopalan B; Shanker M; Scott A; Branch CD; Chada S; Ramesh R
    Cancer Gene Ther; 2008 Jan; 15(1):1-8. PubMed ID: 17828282
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular dynamics simulations elucidate the mode of protein recognition by Skp1 and the F-box domain in the SCF complex.
    Chandra Dantu S; Nathubhai Kachariya N; Kumar A
    Proteins; 2016 Jan; 84(1):159-71. PubMed ID: 26573739
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Polyubiquitination of the B-cell translocation gene 1 and 2 proteins is promoted by the SCF ubiquitin ligase complex containing βTrCP.
    Sasajima H; Nakagawa K; Kashiwayanagi M; Yokosawa H
    Biol Pharm Bull; 2012; 35(9):1539-45. PubMed ID: 22975506
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma.
    Wang XC; Wu YP; Ye B; Lin DC; Feng YB; Zhang ZQ; Xu X; Han YL; Cai Y; Dong JT; Zhan QM; Wu M; Wang MR
    Mol Cancer Res; 2009 Jan; 7(1):12-22. PubMed ID: 19147533
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-Myc.
    Kalra N; Kumar V
    FEBS Lett; 2006 Jan; 580(2):431-6. PubMed ID: 16376880
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Skp2, the FoxO1 hunter.
    Dehan E; Pagano M
    Cancer Cell; 2005 Mar; 7(3):209-10. PubMed ID: 15766658
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.