BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

416 related articles for article (PubMed ID: 16951197)

  • 1. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells.
    Keum YS; Yu S; Chang PP; Yuan X; Kim JH; Xu C; Han J; Agarwal A; Kong AN
    Cancer Res; 2006 Sep; 66(17):8804-13. PubMed ID: 16951197
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.
    Yeh CT; Yen GC
    Carcinogenesis; 2005 Dec; 26(12):2138-48. PubMed ID: 16033772
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protective effect of sulforaphane on indomethacin-induced cytotoxicity via heme oxygenase-1 expression in human intestinal Int 407 cells.
    Yeh CT; Chiu HF; Yen GC
    Mol Nutr Food Res; 2009 Sep; 53(9):1166-76. PubMed ID: 19653226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C; Yuan X; Pan Z; Shen G; Kim JH; Yu S; Khor TO; Li W; Ma J; Kong AN
    Mol Cancer Ther; 2006 Aug; 5(8):1918-26. PubMed ID: 16928811
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells.
    Jeong WS; Keum YS; Chen C; Jain MR; Shen G; Kim JH; Li W; Kong AN
    J Biochem Mol Biol; 2005 Mar; 38(2):167-76. PubMed ID: 15826493
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression.
    Prawan A; Keum YS; Khor TO; Yu S; Nair S; Li W; Hu L; Kong AN
    Pharm Res; 2008 Apr; 25(4):836-44. PubMed ID: 17657593
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition and genetic deficiency of p38 MAPK up-regulates heme oxygenase-1 gene expression via Nrf2.
    Naidu S; Vijayan V; Santoso S; Kietzmann T; Immenschuh S
    J Immunol; 2009 Jun; 182(11):7048-57. PubMed ID: 19454702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p38 MAPK plays a distinct role in sulforaphane-induced up-regulation of ARE-dependent enzymes and down-regulation of COX-2 in human bladder cancer cells.
    Shan Y; Wang X; Wang W; He C; Bao Y
    Oncol Rep; 2010 Apr; 23(4):1133-8. PubMed ID: 20204301
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
    Rojo AI; Medina-Campos ON; Rada P; Zúñiga-Toalá A; López-Gazcón A; Espada S; Pedraza-Chaverri J; Cuadrado A
    Free Radic Biol Med; 2012 Jan; 52(2):473-87. PubMed ID: 22142471
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens.
    Yu R; Mandlekar S; Lei W; Fahl WE; Tan TH; Kong AN
    J Biol Chem; 2000 Jan; 275(4):2322-7. PubMed ID: 10644681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MDA-7/IL-24 inhibits Nrf2-mediated antioxidant response through activation of p38 pathway and inhibition of ERK pathway involved in cancer cell apoptosis.
    Tian H; Zhang D; Gao Z; Li H; Zhang B; Zhang Q; Li L; Cheng Q; Pei D; Zheng J
    Cancer Gene Ther; 2014 Oct; 21(10):416-26. PubMed ID: 25236495
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lipoxin A4-induced heme oxygenase-1 protects cardiomyocytes against hypoxia/reoxygenation injury via p38 MAPK activation and Nrf2/ARE complex.
    Chen XQ; Wu SH; Zhou Y; Tang YR
    PLoS One; 2013; 8(6):e67120. PubMed ID: 23826208
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.
    Lee HH; Park SA; Almazari I; Kim EH; Na HK; Surh YJ
    Arch Biochem Biophys; 2010 Sep; 501(1):142-50. PubMed ID: 20558128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of HO-1 by 5, 8-Dihydroxy-4',7-Dimethoxyflavone via Activation of ROS/p38 MAPK/Nrf2 Attenuates Thrombin-Induced Connective Tissue Growth Factor Expression in Human Cardiac Fibroblasts.
    Yang CC; Hsiao LD; Lin HH; Tseng HC; Situmorang JH; Leu YL; Yang CM
    Oxid Med Cell Longev; 2020; 2020():1080168. PubMed ID: 33343802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway.
    Zhang L; Zhang H; Li X; Jia B; Yang Y; Zhou P; Li P; Chen J
    Phytomedicine; 2016 Dec; 23(14):1806-1813. PubMed ID: 27912883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways.
    Do MT; Kim HG; Khanal T; Choi JH; Kim DH; Jeong TC; Jeong HG
    Toxicol Appl Pharmacol; 2013 Sep; 271(2):229-38. PubMed ID: 23707609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulforaphane inhibits TNF-alpha-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cells.
    Chen XL; Dodd G; Kunsch C
    Inflamm Res; 2009 Aug; 58(8):513-21. PubMed ID: 19277846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sulforaphane induces antioxidative and antiproliferative responses by generating reactive oxygen species in human bronchial epithelial BEAS-2B cells.
    Lee YJ; Lee SH
    J Korean Med Sci; 2011 Nov; 26(11):1474-82. PubMed ID: 22065904
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.
    Chen C; Pung D; Leong V; Hebbar V; Shen G; Nair S; Li W; Kong AN
    Free Radic Biol Med; 2004 Nov; 37(10):1578-90. PubMed ID: 15477009
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor.
    Alam J; Wicks C; Stewart D; Gong P; Touchard C; Otterbein S; Choi AM; Burow ME; Tou J
    J Biol Chem; 2000 Sep; 275(36):27694-702. PubMed ID: 10874044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.