BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 16951198)

  • 1. Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha.
    Qian DZ; Kachhap SK; Collis SJ; Verheul HM; Carducci MA; Atadja P; Pili R
    Cancer Res; 2006 Sep; 66(17):8814-21. PubMed ID: 16951198
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HDAC4 protein regulates HIF1α protein lysine acetylation and cancer cell response to hypoxia.
    Geng H; Harvey CT; Pittsenbarger J; Liu Q; Beer TM; Xue C; Qian DZ
    J Biol Chem; 2011 Nov; 286(44):38095-38102. PubMed ID: 21917920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha.
    Kong X; Lin Z; Liang D; Fath D; Sang N; Caro J
    Mol Cell Biol; 2006 Mar; 26(6):2019-28. PubMed ID: 16507982
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
    Fischer C; Leithner K; Wohlkoenig C; Quehenberger F; Bertsch A; Olschewski A; Olschewski H; Hrzenjak A
    Mol Cancer; 2015 Jan; 14():4. PubMed ID: 25608569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors.
    Pluemsampant S; Safronova OS; Nakahama K; Morita I
    Int J Cancer; 2008 Jan; 122(2):333-41. PubMed ID: 17935135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma.
    Ramakrishnan S; Ku S; Ciamporcero E; Miles KM; Attwood K; Chintala S; Shen L; Ellis L; Sotomayor P; Swetzig W; Huang R; Conroy D; Orillion A; Das G; Pili R
    BMC Cancer; 2016 Aug; 16():617. PubMed ID: 27506904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.
    Mahon PC; Hirota K; Semenza GL
    Genes Dev; 2001 Oct; 15(20):2675-86. PubMed ID: 11641274
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
    Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
    Schoepflin ZR; Shapiro IM; Risbud MV
    J Bone Miner Res; 2016 Jun; 31(6):1287-99. PubMed ID: 26765925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation.
    Hutt DM; Roth DM; Marchal C; Bouchecareilh M
    Methods Mol Biol; 2017; 1510():77-91. PubMed ID: 27761814
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1.
    Seo HW; Kim EJ; Na H; Lee MO
    FEBS Lett; 2009 Jan; 583(1):55-60. PubMed ID: 19071119
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury.
    Noh H; Oh EY; Seo JY; Yu MR; Kim YO; Ha H; Lee HB
    Am J Physiol Renal Physiol; 2009 Sep; 297(3):F729-39. PubMed ID: 19553350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors.
    Khan N; Jeffers M; Kumar S; Hackett C; Boldog F; Khramtsov N; Qian X; Mills E; Berghs SC; Carey N; Finn PW; Collins LS; Tumber A; Ritchie JW; Jensen PB; Lichenstein HS; Sehested M
    Biochem J; 2008 Jan; 409(2):581-9. PubMed ID: 17868033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation.
    Turner KJ; Moore JW; Jones A; Taylor CF; Cuthbert-Heavens D; Han C; Leek RD; Gatter KC; Maxwell PH; Ratcliffe PJ; Cranston D; Harris AL
    Cancer Res; 2002 May; 62(10):2957-61. PubMed ID: 12019178
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors.
    Koppel I; Timmusk T
    Neuropharmacology; 2013 Dec; 75():106-15. PubMed ID: 23916482
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma.
    Chang CC; Lin BR; Chen ST; Hsieh TH; Li YJ; Kuo MY
    J Oral Pathol Med; 2011 Aug; 40(7):567-75. PubMed ID: 21332579
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of the HIF-1alpha stability by histone deacetylases.
    Kim SH; Jeong JW; Park JA; Lee JW; Seo JH; Jung BK; Bae MK; Kim KW
    Oncol Rep; 2007 Mar; 17(3):647-51. PubMed ID: 17273746
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.