122 related articles for article (PubMed ID: 16951407)
1. Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation.
Gastwirt RF; Slavin DA; McAndrew CW; Donoghue DJ
J Biol Chem; 2006 Nov; 281(46):35425-35. PubMed ID: 16951407
[TBL] [Abstract][Full Text] [Related]
2. The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis.
McAndrew CW; Gastwirt RF; Donoghue DJ
Cell Cycle; 2009 Jan; 8(1):66-75. PubMed ID: 19106603
[TBL] [Abstract][Full Text] [Related]
3. Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis.
Gastwirt RF; McAndrew CW; Donoghue DJ
Cell Cycle; 2007 May; 6(10):1188-93. PubMed ID: 17507798
[TBL] [Abstract][Full Text] [Related]
4. Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.
Porter LA; Dellinger RW; Tynan JA; Barnes EA; Kong M; Lenormand JL; Donoghue DJ
J Cell Biol; 2002 Apr; 157(3):357-66. PubMed ID: 11980914
[TBL] [Abstract][Full Text] [Related]
5. Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27.
McAndrew CW; Gastwirt RF; Meyer AN; Porter LA; Donoghue DJ
Cell Cycle; 2007 Aug; 6(15):1937-45. PubMed ID: 17671428
[TBL] [Abstract][Full Text] [Related]
6. Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.
McGrath DA; Fifield BA; Marceau AH; Tripathi S; Porter LA; Rubin SM
EMBO J; 2017 Aug; 36(15):2251-2262. PubMed ID: 28666995
[TBL] [Abstract][Full Text] [Related]
7. Human Spy1 promotes survival of mammalian cells following DNA damage.
Barnes EA; Porter LA; Lenormand JL; Dellinger RW; Donoghue DJ
Cancer Res; 2003 Jul; 63(13):3701-7. PubMed ID: 12839962
[TBL] [Abstract][Full Text] [Related]
8. Spy1, a unique cell cycle regulator, alters viability in ALS motor neurons and cell lines in response to mutant SOD1-induced DNA damage.
Wang XD; Zhu MW; Shan D; Wang SY; Yin X; Yang YQ; Wang TH; Zhang CT; Wang Y; Liang WW; Zhang J; Jiang HZ; Dong GT; Jiang HQ; Qi Y; Feng HL
DNA Repair (Amst); 2019 Feb; 74():51-62. PubMed ID: 30630676
[TBL] [Abstract][Full Text] [Related]
9. Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.
Cheng A; Xiong W; Ferrell JE; Solomon MJ
Cell Cycle; 2005 Jan; 4(1):155-65. PubMed ID: 15611625
[TBL] [Abstract][Full Text] [Related]
10. The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis.
Fifield BA; Qemo I; Kirou E; Cardiff RD; Porter LA
Breast Cancer Res; 2019 Dec; 21(1):140. PubMed ID: 31829284
[TBL] [Abstract][Full Text] [Related]
11. Peripheral nerve lesion induces an up-regulation of Spy1 in rat spinal cord.
Huang Y; Liu Y; Chen Y; Yu X; Yang J; Lu M; Lu Q; Ke Q; Shen A; Yan M
Cell Mol Neurobiol; 2009 May; 29(3):403-11. PubMed ID: 19082704
[TBL] [Abstract][Full Text] [Related]
12. Cell adhesion to fibronectin down-regulates the expression of Spy1 and contributes to drug resistance in multiple myeloma cells.
Fei M; Hang Q; Hou S; Ruan C
Int J Hematol; 2013 Oct; 98(4):446-55. PubMed ID: 24037419
[TBL] [Abstract][Full Text] [Related]
13. Spy1 is frequently overexpressed in malignant gliomas and critically regulates the proliferation of glioma cells.
Zhang L; Shen A; Ke Q; Zhao W; Yan M; Cheng C
J Mol Neurosci; 2012 Jul; 47(3):485-94. PubMed ID: 22447439
[TBL] [Abstract][Full Text] [Related]
14. Speedy: a novel cell cycle regulator of the G2/M transition.
Lenormand JL; Dellinger RW; Knudsen KE; Subramani S; Donoghue DJ
EMBO J; 1999 Apr; 18(7):1869-77. PubMed ID: 10202150
[TBL] [Abstract][Full Text] [Related]
15. Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.
Chow JP; Siu WY; Ho HT; Ma KH; Ho CC; Poon RY
J Biol Chem; 2003 Oct; 278(42):40815-28. PubMed ID: 12912980
[TBL] [Abstract][Full Text] [Related]
16. Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage.
Xu N; Libertini S; Black EJ; Lao Y; Hegarat N; Walker M; Gillespie DA
Oncogene; 2012 Mar; 31(9):1086-94. PubMed ID: 21765472
[TBL] [Abstract][Full Text] [Related]
17. RINGO/Speedy proteins, a family of non-canonical activators of CDK1 and CDK2.
Gonzalez L; Nebreda AR
Semin Cell Dev Biol; 2020 Nov; 107():21-27. PubMed ID: 32317145
[TBL] [Abstract][Full Text] [Related]
18. DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.
Dodson GE; Shi Y; Tibbetts RS
J Biol Chem; 2004 Aug; 279(32):34010-4. PubMed ID: 15197179
[TBL] [Abstract][Full Text] [Related]
19. Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells.
Tu YS; Kang XL; Zhou JG; Lv XF; Tang YB; Guan YY
Eur J Pharmacol; 2011 Nov; 670(2-3):356-64. PubMed ID: 21958871
[TBL] [Abstract][Full Text] [Related]
20. A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation.
Xiao Z; Xue J; Sowin TJ; Rosenberg SH; Zhang H
Oncogene; 2005 Feb; 24(8):1403-11. PubMed ID: 15608676
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
