273 related articles for article (PubMed ID: 16960444)
1. The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents.
Lin C; Ke X; Cvetanovic I; Ranade V; Somberg J
Cardiology; 2007; 108(1):18-27. PubMed ID: 16960444
[TBL] [Abstract][Full Text] [Related]
2. The influence of extracellular acidosis on the effect of IKr blockers.
Lin C; Ke X; Cvetanovic I; Ranade V; Somberg J
J Cardiovasc Pharmacol Ther; 2005 Mar; 10(1):67-76. PubMed ID: 15821840
[TBL] [Abstract][Full Text] [Related]
3. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
Dong DL; Li Z; Wang HZ; Du ZM; Song WH; Yang BF
Basic Clin Pharmacol Toxicol; 2004 May; 94(5):209-12. PubMed ID: 15125690
[TBL] [Abstract][Full Text] [Related]
4. I(Kr) vs. I(Ks) blockade and arrhythmogenicity in normoxic rabbit Purkinje fibers: does it really make a difference?
Puddu PE; Legrand JC; Sallé L; Rouet R; Ducroq J
Fundam Clin Pharmacol; 2011 Jun; 25(3):304-12. PubMed ID: 21241363
[TBL] [Abstract][Full Text] [Related]
5. Electrophysiological and antiarrhythmic effects of the novel I(Kur) channel blockers, S9947 and S20951, on left vs. right pig atrium in vivo in comparison with the I(Kr) blockers dofetilide, azimilide, d,l-sotalol and ibutilide.
Knobloch K; Brendel J; Peukert S; Rosenstein B; Busch AE; Wirth KJ
Naunyn Schmiedebergs Arch Pharmacol; 2002 Nov; 366(5):482-7. PubMed ID: 12382079
[TBL] [Abstract][Full Text] [Related]
6. Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action.
Busch AE; Eigenberger B; Jurkiewicz NK; Salata JJ; Pica A; Suessbrich H; Lang F
Br J Pharmacol; 1998 Jan; 123(1):23-30. PubMed ID: 9484850
[TBL] [Abstract][Full Text] [Related]
7. Comparative effects of increased extracellular potassium and pacing frequency on the class III activities of methanesulfonanilide IKr blockers dofetilide, D-sotalol, E-4031, and MK-499.
Baskin EP; Lynch JJ
J Cardiovasc Pharmacol; 1994 Aug; 24(2):199-208. PubMed ID: 7526051
[TBL] [Abstract][Full Text] [Related]
8. Sensitivity of the slow component of the delayed rectifier potassium current (IKs) to potassium channel blockers: implications for clinical reverse use-dependent effects.
Lai L; Su M; Tseng Y; Lien W
J Biomed Sci; 1999; 6(4):251-9. PubMed ID: 10420082
[TBL] [Abstract][Full Text] [Related]
9. Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.
Guérard NC; Traebert M; Suter W; Dumotier BM
J Pharmacol Toxicol Methods; 2008; 58(1):32-40. PubMed ID: 18582585
[TBL] [Abstract][Full Text] [Related]
10. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.
Kiehn J; Lacerda AE; Wible B; Brown AM
Circulation; 1996 Nov; 94(10):2572-9. PubMed ID: 8921803
[TBL] [Abstract][Full Text] [Related]
11. Azimilide causes reverse rate-dependent block while reducing both components of delayed-rectifier current in canine ventricular myocytes.
Gintant GA
J Cardiovasc Pharmacol; 1998 Jun; 31(6):945-53. PubMed ID: 9641481
[TBL] [Abstract][Full Text] [Related]
12. Molecular determinants of dofetilide block of HERG K+ channels.
Ficker E; Jarolimek W; Kiehn J; Baumann A; Brown AM
Circ Res; 1998 Feb; 82(3):386-95. PubMed ID: 9486667
[TBL] [Abstract][Full Text] [Related]
13. Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.
Knobloch K; Brendel J; Rosenstein B; Bleich M; Busch AE; Wirth KJ
Med Sci Monit; 2004 Jul; 10(7):BR221-8. PubMed ID: 15232496
[TBL] [Abstract][Full Text] [Related]
14. Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide.
Lee K; Park JB; Jeon BH; Kim KJ; Ryu PD; Kwon LS; Kim HY
J Cardiovasc Pharmacol; 2003 Nov; 42(5):648-55. PubMed ID: 14576514
[TBL] [Abstract][Full Text] [Related]
15. Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.
Yang BF; Xu DH; Xu CQ; Li Z; Du ZM; Wang HZ; Dong DL
Acta Pharmacol Sin; 2004 May; 25(5):554-60. PubMed ID: 15132818
[TBL] [Abstract][Full Text] [Related]
16. A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels.
Lin C; Cvetanovic I; Ke X; Ranade V; Somberg J
Am J Ther; 2005; 12(4):328-36. PubMed ID: 16041196
[TBL] [Abstract][Full Text] [Related]
17. Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide.
Lin C; Ke X; Ranade V; Somberg J
Cardiology; 2008; 110(3):209-16. PubMed ID: 18057887
[TBL] [Abstract][Full Text] [Related]
18. Azimilide (NE-10064) can prolong or shorten the action potential duration in canine ventricular myocytes: dependence on blockade of K, Ca, and Na channels.
Yao JA; Tseng GN
J Cardiovasc Electrophysiol; 1997 Feb; 8(2):184-98. PubMed ID: 9048249
[TBL] [Abstract][Full Text] [Related]
19. Azimilide and dofetilide produce similar electrophysiological and proarrhythmic effects in a canine model of Torsade de Pointes arrhythmias.
Van Opstal JM; Leunissen JD; Wellens HJ; Vos MA
Eur J Pharmacol; 2001 Jan; 412(1):67-76. PubMed ID: 11166738
[TBL] [Abstract][Full Text] [Related]
20. Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence.
Yang T; Roden DM
Circulation; 1996 Feb; 93(3):407-11. PubMed ID: 8565156
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]