BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 16961404)

  • 1. Application of lean manufacturing concepts to drug discovery: rapid analogue library synthesis.
    Weller HN; Nirschl DS; Petrillo EW; Poss MA; Andres CJ; Cavallaro CL; Echols MM; Grant-Young KA; Houston JG; Miller AV; Swann RT
    J Comb Chem; 2006; 8(5):664-9. PubMed ID: 16961404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Current directions in the evolution of compound libraries.
    Webb TR
    Curr Opin Drug Discov Devel; 2005 May; 8(3):303-8. PubMed ID: 15892244
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthetic library design.
    Huwe CM
    Drug Discov Today; 2006 Aug; 11(15-16):763-7. PubMed ID: 16846805
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combinatorial compound libraries for drug discovery: an ongoing challenge.
    Geysen HM; Schoenen F; Wagner D; Wagner R
    Nat Rev Drug Discov; 2003 Mar; 2(3):222-30. PubMed ID: 12612648
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-directed combinatorial library design.
    Zhou JZ
    Curr Opin Chem Biol; 2008 Jun; 12(3):379-85. PubMed ID: 18328830
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization.
    Kattar SD; Surdi LM; Zabierek A; Methot JL; Middleton RE; Hughes B; Szewczak AA; Dahlberg WK; Kral AM; Ozerova N; Fleming JC; Wang H; Secrist P; Harsch A; Hamill JE; Cruz JC; Kenific CM; Chenard M; Miller TA; Berk SC; Tempest P
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1168-72. PubMed ID: 19138845
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combinatorial approaches to formulation development.
    Alakhov V; Pietrzynski G; Kabanov A
    Curr Opin Drug Discov Devel; 2001 Jul; 4(4):493-501. PubMed ID: 11727314
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The impact of combinatorial chemistry on drug discovery.
    Lee A; Breitenbucher JG
    Curr Opin Drug Discov Devel; 2003 Jul; 6(4):494-508. PubMed ID: 12951813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Emerging chemical and biological approaches for the preparation of discovery libraries.
    Boldt GE; Dickerson TJ; Janda KD
    Drug Discov Today; 2006 Feb; 11(3-4):143-8. PubMed ID: 16533712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A scalable approach to combinatorial library design for drug discovery.
    Sharma P; Salapaka S; Beck C
    J Chem Inf Model; 2008 Jan; 48(1):27-41. PubMed ID: 18052333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insecticidal lead identification by screening benzopyrano[4,3-c] pyrazol-3(2H)-ones library constructed from multiple-parallel synthesis under microwave irradiation.
    Zhou ZZ; Yang GF
    Bioorg Med Chem; 2006 Dec; 14(24):8666-74. PubMed ID: 16949292
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enriching chemical space with diversity-oriented synthesis.
    Thomas GL; Wyatt EE; Spring DR
    Curr Opin Drug Discov Devel; 2006 Nov; 9(6):700-12. PubMed ID: 17117681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent trends in library design: 'rational design' revisited.
    Schnur DM
    Curr Opin Drug Discov Devel; 2008 May; 11(3):375-80. PubMed ID: 18428091
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biosynthetic engineering of natural products for lead optimization and development.
    Wilkinson B; Moss SJ
    Curr Opin Drug Discov Devel; 2005 Nov; 8(6):748-56. PubMed ID: 16312150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Concept of combinatorial de novo design of drug-like molecules by particle swarm optimization.
    Hartenfeller M; Proschak E; Schüller A; Schneider G
    Chem Biol Drug Des; 2008 Jul; 72(1):16-26. PubMed ID: 18564216
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simulated annealing: an effective stochastic optimization approach to computational library design.
    Zheng W
    Methods Mol Biol; 2004; 275():379-98. PubMed ID: 15141122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The synergy between combinatorial chemistry and high-throughput screening.
    Diller DJ
    Curr Opin Drug Discov Devel; 2008 May; 11(3):346-55. PubMed ID: 18428088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular conceptor for training in medicinal chemistry, drug design, and cheminformatics.
    Cohen C; Fischel O; Cohen E
    Chem Biol Drug Des; 2007 Jan; 69(1):75-82. PubMed ID: 17313460
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A review of high throughput technology for the screening of natural products.
    Mishra KP; Ganju L; Sairam M; Banerjee PK; Sawhney RC
    Biomed Pharmacother; 2008 Feb; 62(2):94-8. PubMed ID: 17692498
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Similarity searching and scaffold hopping in synthetically accessible combinatorial chemistry spaces.
    Boehm M; Wu TY; Claussen H; Lemmen C
    J Med Chem; 2008 Apr; 51(8):2468-80. PubMed ID: 18380426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.