294 related articles for article (PubMed ID: 16962227)
1. Evaluation of monoquaternary pyridinium oximes potency to reactivate tabun-inhibited human acetylcholinesterase.
Odzak R; Calić M; Hrenar T; Primozic I; Kovarik Z
Toxicology; 2007 Apr; 233(1-3):85-96. PubMed ID: 16962227
[TBL] [Abstract][Full Text] [Related]
2. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity.
Calić M; Vrdoljak AL; Radić B; Jelić D; Jun D; Kuca K; Kovarik Z
Toxicology; 2006 Feb; 219(1-3):85-96. PubMed ID: 16332406
[TBL] [Abstract][Full Text] [Related]
3. In vitro reactivation of tabun-inhibited acetylcholinesterase using new oximes--K027, K005, K033 and K048.
Kuca K; Cabal J
Cent Eur J Public Health; 2004 Mar; 12 Suppl():S59-61. PubMed ID: 15141981
[TBL] [Abstract][Full Text] [Related]
4. Effective bisquaternary reactivators of tabun-inhibited AChE.
Kuca K; Cabal J; Musilek K; Jun D; Bajgar J
J Appl Toxicol; 2005; 25(6):491-5. PubMed ID: 16092078
[TBL] [Abstract][Full Text] [Related]
5. Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Musilek K; Holas O; Kuca K; Jun D; Dohnal V; Opletalova V; Dolezal M
Bioorg Med Chem Lett; 2007 Jun; 17(11):3172-6. PubMed ID: 17383875
[TBL] [Abstract][Full Text] [Related]
6. In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties.
Bhattacharjee AK; Kuca K; Musilek K; Gordon RK
Chem Res Toxicol; 2010 Jan; 23(1):26-36. PubMed ID: 20028185
[TBL] [Abstract][Full Text] [Related]
7. New oxime reactivators connected with CH2O(CH2)nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase.
Yang GY; Oh KA; Park NJ; Jung YS
Bioorg Med Chem; 2007 Dec; 15(24):7704-10. PubMed ID: 17869525
[TBL] [Abstract][Full Text] [Related]
8. Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study.
Kuca K; Jun D; Cabal J; Musilova L
Basic Clin Pharmacol Toxicol; 2007 Jul; 101(1):25-8. PubMed ID: 17577312
[TBL] [Abstract][Full Text] [Related]
9. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
Kassa J; Karasova J; Musilek K; Kuca K
Toxicology; 2008 Jan; 243(3):311-6. PubMed ID: 18054821
[TBL] [Abstract][Full Text] [Related]
10. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
Aurbek N; Herkert NM; Koller M; Thiermann H; Worek F
Chem Biol Interact; 2010 Sep; 187(1-3):215-9. PubMed ID: 20105433
[TBL] [Abstract][Full Text] [Related]
11. Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis.
Artursson E; Akfur C; Hörnberg A; Worek F; Ekström F
Toxicology; 2009 Nov; 265(3):108-14. PubMed ID: 19761810
[TBL] [Abstract][Full Text] [Related]
12. Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes.
Oh KA; Park NJ; Park NS; Kuca K; Jun D; Jung YS
Chem Biol Interact; 2008 Sep; 175(1-3):365-7. PubMed ID: 18565503
[TBL] [Abstract][Full Text] [Related]
13. Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning.
Lucić Vrdoljak A; Calić M; Radić B; Berend S; Jun D; Kuca K; Kovarik Z
Toxicology; 2006 Nov; 228(1):41-50. PubMed ID: 16982122
[TBL] [Abstract][Full Text] [Related]
14. Effect of five acetylcholinesterase reactivators on tabun-intoxicated rats: induction of oxidative stress versus reactivation efficacy.
Pohanka M; Karasova JZ; Musilek K; Kuca K; Kassa J
J Appl Toxicol; 2009 Aug; 29(6):483-8. PubMed ID: 19338015
[TBL] [Abstract][Full Text] [Related]
15. Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning.
Kovarik Z; Calić M; Sinko G; Bosak A; Berend S; Vrdoljak AL; Radić B
Chem Biol Interact; 2008 Sep; 175(1-3):173-9. PubMed ID: 18501341
[TBL] [Abstract][Full Text] [Related]
16. Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases.
Calić M; Bosak A; Kuca K; Kovarik Z
Chem Biol Interact; 2008 Sep; 175(1-3):305-8. PubMed ID: 18501885
[TBL] [Abstract][Full Text] [Related]
17. Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates.
Ekström F; Pang YP; Boman M; Artursson E; Akfur C; Börjegren S
Biochem Pharmacol; 2006 Aug; 72(5):597-607. PubMed ID: 16876764
[TBL] [Abstract][Full Text] [Related]
18. Monooxime-monocarbamoyl Bispyridinium Xylene-Linked Reactivators of Acetylcholinesterase-Synthesis, In vitro and Toxicity Evaluation, and Docking Studies.
Musilek K; Holas O; Misik J; Pohanka M; Novotny L; Dohnal V; Opletalova V; Kuca K
ChemMedChem; 2010 Feb; 5(2):247-54. PubMed ID: 20058292
[TBL] [Abstract][Full Text] [Related]
19. Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase.
Kovarik Z; Katalinić M; Sinko G; Binder J; Holas O; Jung YS; Musilova L; Jun D; Kuca K
Chem Biol Interact; 2010 Sep; 187(1-3):167-71. PubMed ID: 20206154
[TBL] [Abstract][Full Text] [Related]
20. Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase.
Cabal J; Kuca K; Kassa J
Basic Clin Pharmacol Toxicol; 2004 Aug; 95(2):81-6. PubMed ID: 15379785
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
