BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 16963448)

  • 1. Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function.
    Chini CC; Chen J
    J Biol Chem; 2006 Nov; 281(44):33276-82. PubMed ID: 16963448
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase.
    Lindsey-Boltz LA; Serçin O; Choi JH; Sancar A
    J Biol Chem; 2009 Nov; 284(48):33107-14. PubMed ID: 19828454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system.
    Clarke CA; Clarke PR
    Biochem J; 2005 Jun; 388(Pt 2):705-12. PubMed ID: 15707391
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylated claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation.
    Jeong SY; Kumagai A; Lee J; Dunphy WG
    J Biol Chem; 2003 Nov; 278(47):46782-8. PubMed ID: 12963733
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1.
    Kumagai A; Dunphy WG
    Nat Cell Biol; 2003 Feb; 5(2):161-5. PubMed ID: 12545175
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1.
    Kumagai A; Kim SM; Dunphy WG
    J Biol Chem; 2004 Nov; 279(48):49599-608. PubMed ID: 15371427
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1.
    Bennett LN; Larkin C; Gillespie DA; Clarke PR
    Biochem Biophys Res Commun; 2008 May; 369(3):973-6. PubMed ID: 18331829
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response.
    Lin YF; Shih HY; Shang Z; Matsunaga S; Chen BP
    Nucleic Acids Res; 2014 Apr; 42(7):4463-73. PubMed ID: 24500207
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.
    Clarke CA; Bennett LN; Clarke PR
    J Biol Chem; 2005 Oct; 280(42):35337-45. PubMed ID: 16123041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress.
    Wang X; Zou L; Lu T; Bao S; Hurov KE; Hittelman WN; Elledge SJ; Li L
    Mol Cell; 2006 Aug; 23(3):331-41. PubMed ID: 16885023
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation.
    Liu S; Bekker-Jensen S; Mailand N; Lukas C; Bartek J; Lukas J
    Mol Cell Biol; 2006 Aug; 26(16):6056-64. PubMed ID: 16880517
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human claspin is required for replication checkpoint control.
    Chini CC; Chen J
    J Biol Chem; 2003 Aug; 278(32):30057-62. PubMed ID: 12766152
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The conserved C terminus of Claspin interacts with Rad9 and promotes rapid activation of Chk1.
    Liu S; Song N; Zou L
    Cell Cycle; 2012 Jul; 11(14):2711-6. PubMed ID: 22732499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drosophila Claspin is required for the G2 arrest that is induced by DNA replication stress but not by DNA double-strand breaks.
    Lee EM; Trinh TT; Shim HJ; Park SY; Nguyen TT; Kim MJ; Song YH
    DNA Repair (Amst); 2012 Sep; 11(9):741-52. PubMed ID: 22796626
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells.
    Rodríguez-Bravo V; Guaita-Esteruelas S; Florensa R; Bachs O; Agell N
    Cancer Res; 2006 Sep; 66(17):8672-9. PubMed ID: 16951182
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures.
    Yoo HY; Jeong SY; Dunphy WG
    Genes Dev; 2006 Apr; 20(7):772-83. PubMed ID: 16547171
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.
    Sørensen CS; Syljuåsen RG; Lukas J; Bartek J
    Cell Cycle; 2004 Jul; 3(7):941-5. PubMed ID: 15190204
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Claspin and Chk1 regulate replication fork stability by different mechanisms.
    Scorah J; McGowan CH
    Cell Cycle; 2009 Apr; 8(7):1036-43. PubMed ID: 19270516
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Claspin, a regulator of Chk1 in DNA replication stress pathway.
    Chini CC; Chen J
    DNA Repair (Amst); 2004; 3(8-9):1033-7. PubMed ID: 15279790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response.
    Lee J; Gold DA; Shevchenko A; Shevchenko A; Dunphy WG
    Mol Biol Cell; 2005 Nov; 16(11):5269-82. PubMed ID: 16148040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.