252 related articles for article (PubMed ID: 16964586)
1. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes.
Dvorák Z; Maurel P; Vilarem MJ; Ulrichová J; Modrianský M
Cell Biol Toxicol; 2007 Mar; 23(2):63-73. PubMed ID: 16964586
[TBL] [Abstract][Full Text] [Related]
2. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C; Daujat-Chavanieu M; Pascussi JM; Pichard-Garcia L; Balaguer P; Fabre JM; Vilarem MJ; Maurel P; Gerbal-Chaloin S
Mol Pharmacol; 2006 Jul; 70(1):329-39. PubMed ID: 16608920
[TBL] [Abstract][Full Text] [Related]
3. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
[TBL] [Abstract][Full Text] [Related]
4. Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 female-predominant expression by glucocorticoid hormone.
Bhadhprasit W; Sakuma T; Hatakeyama N; Fuwa M; Kitajima K; Nemoto N
Drug Metab Dispos; 2007 Oct; 35(10):1880-5. PubMed ID: 17640954
[TBL] [Abstract][Full Text] [Related]
5. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
Dvorak Z; Modriansky M; Pichard-Garcia L; Balaguer P; Vilarem MJ; Ulrichová J; Maurel P; Pascussi JM
Mol Pharmacol; 2003 Jul; 64(1):160-9. PubMed ID: 12815172
[TBL] [Abstract][Full Text] [Related]
6. Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors.
Falkner KC; Pinaire JA; Xiao GH; Geoghegan TE; Prough RA
Mol Pharmacol; 2001 Sep; 60(3):611-9. PubMed ID: 11502894
[TBL] [Abstract][Full Text] [Related]
7. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
Wyde ME; Bartolucci E; Ueda A; Zhang H; Yan B; Negishi M; You L
Mol Pharmacol; 2003 Aug; 64(2):474-81. PubMed ID: 12869653
[TBL] [Abstract][Full Text] [Related]
8. Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.
Aouabdi S; Gibson G; Plant N
Drug Metab Dispos; 2006 Jan; 34(1):138-44. PubMed ID: 16243957
[TBL] [Abstract][Full Text] [Related]
9. Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver.
Al-Dosari MS; Knapp JE; Liu D
Mol Pharm; 2006; 3(3):322-8. PubMed ID: 16749864
[TBL] [Abstract][Full Text] [Related]
10. Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.
Bachleda P; Vrzal R; Pivnicka J; Cvek B; Dvorak Z
Toxicol Lett; 2009 Dec; 191(1):74-8. PubMed ID: 19686824
[TBL] [Abstract][Full Text] [Related]
11. Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes.
Pascussi JM; Gerbal-Chaloin S; Pichard-Garcia L; Daujat M; Fabre JM; Maurel P; Vilarem MJ
Biochem Biophys Res Commun; 2000 Aug; 274(3):707-13. PubMed ID: 10924340
[TBL] [Abstract][Full Text] [Related]
12. Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression.
Vyhlidal CA; Gaedigk R; Leeder JS
Drug Metab Dispos; 2006 Jan; 34(1):131-7. PubMed ID: 16243958
[TBL] [Abstract][Full Text] [Related]
13. Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance.
Assenat E; Gerbal-Chaloin S; Larrey D; Saric J; Fabre JM; Maurel P; Vilarem MJ; Pascussi JM
Hepatology; 2004 Oct; 40(4):951-60. PubMed ID: 15382119
[TBL] [Abstract][Full Text] [Related]
14. Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
Hariparsad N; Carr BA; Evers R; Chu X
Drug Metab Dispos; 2008 Jun; 36(6):1046-55. PubMed ID: 18332078
[TBL] [Abstract][Full Text] [Related]
15. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
[TBL] [Abstract][Full Text] [Related]
16. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
Anakk S; Huang W; Staudinger JL; Tan K; Cole TJ; Moore DD; Strobel HW
Drug Metab Dispos; 2007 Jan; 35(1):36-42. PubMed ID: 17020958
[TBL] [Abstract][Full Text] [Related]
17. Species-specific activation of nuclear receptors correlates with the response of liver drug metabolizing enzymes to EMD 392949 in vitro.
Mueller SO; Fery Y; Tuschl G; Schrenk D
Toxicol Lett; 2010 Mar; 193(1):120-3. PubMed ID: 20035846
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.
Sugatani J; Nishitani S; Yamakawa K; Yoshinari K; Sueyoshi T; Negishi M; Miwa M
Mol Pharmacol; 2005 Mar; 67(3):845-55. PubMed ID: 15557560
[TBL] [Abstract][Full Text] [Related]
19. Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver.
Guo D; Sarkar J; Ahmed MR; Viswakarma N; Jia Y; Yu S; Sambasiva Rao M; Reddy JK
Biochem Biophys Res Commun; 2006 Aug; 347(2):485-95. PubMed ID: 16828057
[TBL] [Abstract][Full Text] [Related]
20. A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression.
Burk O; Arnold KA; Geick A; Tegude H; Eichelbaum M
Biol Chem; 2005 Jun; 386(6):503-13. PubMed ID: 16006237
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
