379 related articles for article (PubMed ID: 16965178)
1. Designing siRNA that distinguish between genes that differ by a single nucleotide.
Schwarz DS; Ding H; Kennington L; Moore JT; Schelter J; Burchard J; Linsley PS; Aronin N; Xu Z; Zamore PD
PLoS Genet; 2006 Sep; 2(9):e140. PubMed ID: 16965178
[TBL] [Abstract][Full Text] [Related]
2. Design of functional small interfering RNAs targeting amyotrophic lateral sclerosis-associated mutant alleles.
Geng CM; Ding HL
Chin Med J (Engl); 2011 Jan; 124(1):106-10. PubMed ID: 21362317
[TBL] [Abstract][Full Text] [Related]
3. Double-mismatched siRNAs enhance selective gene silencing of a mutant ALS-causing allele.
Geng CM; Ding HL
Acta Pharmacol Sin; 2008 Feb; 29(2):211-6. PubMed ID: 18215350
[TBL] [Abstract][Full Text] [Related]
4. Enhancement of allele discrimination by introduction of nucleotide mismatches into siRNA in allele-specific gene silencing by RNAi.
Ohnishi Y; Tamura Y; Yoshida M; Tokunaga K; Hohjoh H
PLoS One; 2008 May; 3(5):e2248. PubMed ID: 18493311
[TBL] [Abstract][Full Text] [Related]
5. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis.
Ding H; Schwarz DS; Keene A; Affar el B; Fenton L; Xia X; Shi Y; Zamore PD; Xu Z
Aging Cell; 2003 Aug; 2(4):209-17. PubMed ID: 12934714
[TBL] [Abstract][Full Text] [Related]
6. Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs.
Huang H; Qiao R; Zhao D; Zhang T; Li Y; Yi F; Lai F; Hong J; Ding X; Yang Z; Zhang L; Du Q; Liang Z
Nucleic Acids Res; 2009 Dec; 37(22):7560-9. PubMed ID: 19815667
[TBL] [Abstract][Full Text] [Related]
7. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
Maxwell MM; Pasinelli P; Kazantsev AG; Brown RH
Proc Natl Acad Sci U S A; 2004 Mar; 101(9):3178-83. PubMed ID: 14981234
[TBL] [Abstract][Full Text] [Related]
8. The siRNA Non-seed Region and Its Target Sequences Are Auxiliary Determinants of Off-Target Effects.
Kamola PJ; Nakano Y; Takahashi T; Wilson PA; Ui-Tei K
PLoS Comput Biol; 2015 Dec; 11(12):e1004656. PubMed ID: 26657993
[TBL] [Abstract][Full Text] [Related]
9. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites.
Du Q; Thonberg H; Wang J; Wahlestedt C; Liang Z
Nucleic Acids Res; 2005; 33(5):1671-7. PubMed ID: 15781493
[TBL] [Abstract][Full Text] [Related]
10. Designing of highly effective complementary and mismatch siRNAs for silencing a gene.
Ahmed F; Raghava GP
PLoS One; 2011; 6(8):e23443. PubMed ID: 21853133
[TBL] [Abstract][Full Text] [Related]
11. Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo.
Xia X; Zhou H; Huang Y; Xu Z
Neurobiol Dis; 2006 Sep; 23(3):578-86. PubMed ID: 16857362
[TBL] [Abstract][Full Text] [Related]
12. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate.
Elbashir SM; Martinez J; Patkaniowska A; Lendeckel W; Tuschl T
EMBO J; 2001 Dec; 20(23):6877-88. PubMed ID: 11726523
[TBL] [Abstract][Full Text] [Related]
13. [RNAi and neurological disease].
Yokota T
Rinsho Shinkeigaku; 2005 Nov; 45(11):973-5. PubMed ID: 16447777
[TBL] [Abstract][Full Text] [Related]
14. siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme.
Yokota T; Miyagishi M; Hino T; Matsumura R; Tasinato A; Urushitani M; Rao RV; Takahashi R; Bredesen DE; Taira K; Mizusawa H
Biochem Biophys Res Commun; 2004 Jan; 314(1):283-91. PubMed ID: 14715277
[TBL] [Abstract][Full Text] [Related]
15. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.
Harborth J; Elbashir SM; Vandenburgh K; Manninga H; Scaringe SA; Weber K; Tuschl T
Antisense Nucleic Acid Drug Dev; 2003 Apr; 13(2):83-105. PubMed ID: 12804036
[TBL] [Abstract][Full Text] [Related]
16. Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs.
Hu J; Liu J; Yu D; Aiba Y; Lee S; Pendergraff H; Boubaker J; Artates JW; Lagier-Tourenne C; Lima WF; Swayze EE; Prakash TP; Corey DR
Nucleic Acid Ther; 2014 Jun; 24(3):199-209. PubMed ID: 24694346
[TBL] [Abstract][Full Text] [Related]
17. Modified siRNA structure with a single nucleotide bulge overcomes conventional siRNA-mediated off-target silencing.
Dua P; Yoo JW; Kim S; Lee DK
Mol Ther; 2011 Sep; 19(9):1676-87. PubMed ID: 21673662
[TBL] [Abstract][Full Text] [Related]
18. Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.
Sierant M; Paduszynska A; Kazmierczak-Baranska J; Nacmias B; Sorbi S; Bagnoli S; Sochacka E; Nawrot B
Int J Alzheimers Dis; 2011 Apr; 2011():809218. PubMed ID: 21559198
[TBL] [Abstract][Full Text] [Related]
19. siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect.
Naito Y; Yoshimura J; Morishita S; Ui-Tei K
BMC Bioinformatics; 2009 Nov; 10():392. PubMed ID: 19948054
[TBL] [Abstract][Full Text] [Related]
20. Expression profiling reveals off-target gene regulation by RNAi.
Jackson AL; Bartz SR; Schelter J; Kobayashi SV; Burchard J; Mao M; Li B; Cavet G; Linsley PS
Nat Biotechnol; 2003 Jun; 21(6):635-7. PubMed ID: 12754523
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]