These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 16966613)

  • 1. Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.
    Timmerbeul I; Garrett-Engele CM; Kossatz U; Chen X; Firpo E; Grünwald V; Kamino K; Wilkens L; Lehmann U; Buer J; Geffers R; Kubicka S; Manns MP; Porter PL; Roberts JM; Malek NP
    Proc Natl Acad Sci U S A; 2006 Sep; 103(38):14009-14. PubMed ID: 16966613
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer.
    Zhao H; Lu Z; Bauzon F; Fu H; Cui J; Locker J; Zhu L
    Oncogene; 2017 Jan; 36(1):60-70. PubMed ID: 27181203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
    Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
    Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
    Huang KT; Pavlides SC; Lecanda J; Blank SV; Mittal KR; Gold LI
    PLoS One; 2012; 7(9):e46072. PubMed ID: 23029392
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma.
    Wang J; Aldahamsheh O; Ferrena A; Borjihan H; Singla A; Yaguare S; Singh S; Viscarret V; Tingling J; Zi X; Lo Y; Gorlick R; Zheng D; Schwartz EL; Zhao H; Yang R; Geller DS; Hoang BH
    Ann N Y Acad Sci; 2021 Apr; 1490(1):90-104. PubMed ID: 33594717
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Skp2-mediated p27(Kip1) degradation during S/G2 phase progression of adipocyte hyperplasia.
    Auld CA; Fernandes KM; Morrison RF
    J Cell Physiol; 2007 Apr; 211(1):101-11. PubMed ID: 17096381
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation.
    Li Z; Huang J; Yuan H; Chen Z; Luo Q; Lu S
    Oncotarget; 2016 Apr; 7(14):18927-39. PubMed ID: 26942878
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
    Lwin T; Hazlehurst LA; Dessureault S; Lai R; Bai W; Sotomayor E; Moscinski LC; Dalton WS; Tao J
    Blood; 2007 Sep; 110(5):1631-8. PubMed ID: 17502456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Skp2 inversely correlates with p27 and tuberin in transformed cells.
    Rosner M; Hanneder M; Siegel N; Valli A; Fuchs C; Hengstschläger M
    Amino Acids; 2009 Jul; 37(2):257-62. PubMed ID: 18604603
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1.
    Ungermannova D; Lee J; Zhang G; Dallmann HG; McHenry CS; Liu X
    J Biomol Screen; 2013 Sep; 18(8):910-20. PubMed ID: 23589337
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.
    Kelly-Spratt KS; Philipp-Staheli J; Gurley KE; Hoon-Kim K; Knoblaugh S; Kemp CJ
    Oncogene; 2009 Oct; 28(41):3652-62. PubMed ID: 19648963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells.
    Lee JJ; Lee JS; Cui MN; Yun HH; Kim HY; Lee SH; Lee JH
    Cell Death Dis; 2014 Nov; 5(11):e1537. PubMed ID: 25412315
    [TBL] [Abstract][Full Text] [Related]  

  • 13. STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells.
    Wang S; Raven JF; Koromilas AE
    Mol Cancer Res; 2010 May; 8(5):798-805. PubMed ID: 20407011
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells.
    Chung YK; Chi-Hung Or R; Lu CH; Ouyang WT; Yang SY; Chang CC
    J Biosci Bioeng; 2015 Jan; 119(1):35-42. PubMed ID: 25070589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer.
    Bochis OV; Irimie A; Pichler M; Berindan-Neagoe I
    J Gastrointestin Liver Dis; 2015 Jun; 24(2):225-34. PubMed ID: 26114183
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [The degradation of p27 and cancer].
    Kotoshiba S; Nakayama K
    Nihon Rinsho; 2005 Nov; 63(11):2047-56. PubMed ID: 16277271
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specific small molecule inhibitors of Skp2-mediated p27 degradation.
    Wu L; Grigoryan AV; Li Y; Hao B; Pagano M; Cardozo TJ
    Chem Biol; 2012 Dec; 19(12):1515-24. PubMed ID: 23261596
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication.
    Iwahori S; Murata T; Kudoh A; Sato Y; Nakayama S; Isomura H; Kanda T; Tsurumi T
    J Biol Chem; 2009 Jul; 284(28):18923-31. PubMed ID: 19451650
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.
    Miranda-Carboni GA; Krum SA; Yee K; Nava M; Deng QE; Pervin S; Collado-Hidalgo A; Galic Z; Zack JA; Nakayama K; Nakayama KI; Lane TF
    Genes Dev; 2008 Nov; 22(22):3121-34. PubMed ID: 19056892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells.
    Bhatt KV; Hu R; Spofford LS; Aplin AE
    Oncogene; 2007 Feb; 26(7):1056-66. PubMed ID: 16924241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.