350 related articles for article (PubMed ID: 16966681)
1. The Parkinson disease gene LRRK2: evolutionary and structural insights.
Marín I
Mol Biol Evol; 2006 Dec; 23(12):2423-33. PubMed ID: 16966681
[TBL] [Abstract][Full Text] [Related]
2. Conformational heterogeneity of the Roc domains in C. tepidum Roc-COR and implications for human LRRK2 Parkinson mutations.
Rudi K; Ho FY; Gilsbach BK; Pots H; Wittinghofer A; Kortholt A; Klare JP
Biosci Rep; 2015 Aug; 35(5):. PubMed ID: 26310572
[TBL] [Abstract][Full Text] [Related]
3. Ancient origin of the Parkinson disease gene LRRK2.
Marín I
J Mol Evol; 2008 Jul; 67(1):41-50. PubMed ID: 18523712
[TBL] [Abstract][Full Text] [Related]
4. The Roco protein family: a functional perspective.
Marín I; van Egmond WN; van Haastert PJ
FASEB J; 2008 Sep; 22(9):3103-10. PubMed ID: 18523161
[TBL] [Abstract][Full Text] [Related]
5. Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?
Civiero L; Bubacco L
Biochem Soc Trans; 2012 Oct; 40(5):1095-101. PubMed ID: 22988872
[TBL] [Abstract][Full Text] [Related]
6. Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.
Klein CL; Rovelli G; Springer W; Schall C; Gasser T; Kahle PJ
J Neurochem; 2009 Nov; 111(3):703-15. PubMed ID: 19712061
[TBL] [Abstract][Full Text] [Related]
7. Revisiting the Roco G-protein cycle.
Terheyden S; Ho FY; Gilsbach BK; Wittinghofer A; Kortholt A
Biochem J; 2015 Jan; 465(1):139-47. PubMed ID: 25317655
[TBL] [Abstract][Full Text] [Related]
8. Prediction of the repeat domain structures and impact of parkinsonism-associated variations on structure and function of all functional domains of leucine-rich repeat kinase 2 (LRRK2).
Mills RD; Mulhern TD; Liu F; Culvenor JG; Cheng HC
Hum Mutat; 2014 Apr; 35(4):395-412. PubMed ID: 24470158
[TBL] [Abstract][Full Text] [Related]
9. Roco Proteins: GTPases with a Baroque Structure and Mechanism.
Wauters L; Versées W; Kortholt A
Int J Mol Sci; 2019 Jan; 20(1):. PubMed ID: 30609797
[TBL] [Abstract][Full Text] [Related]
10. Understanding the GTPase Activity of LRRK2: Regulation, Function, and Neurotoxicity.
Nguyen AP; Moore DJ
Adv Neurobiol; 2017; 14():71-88. PubMed ID: 28353279
[TBL] [Abstract][Full Text] [Related]
11. Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations.
Mills RD; Mulhern TD; Cheng HC; Culvenor JG
Biochem Soc Trans; 2012 Oct; 40(5):1086-9. PubMed ID: 22988870
[TBL] [Abstract][Full Text] [Related]
12. ROCO kinase activity is controlled by internal GTPase function.
Weiss B
Sci Signal; 2008 Jun; 1(23):pe27. PubMed ID: 18544747
[TBL] [Abstract][Full Text] [Related]
13. The Roc-COR tandem domain of leucine-rich repeat kinase 2 forms dimers and exhibits conventional Ras-like GTPase properties.
Mills RD; Liang LY; Lio DS; Mok YF; Mulhern TD; Cao G; Griffin M; Kenche VB; Culvenor JG; Cheng HC
J Neurochem; 2018 Nov; 147(3):409-428. PubMed ID: 30091236
[TBL] [Abstract][Full Text] [Related]
14. Contribution of GTPase activity to LRRK2-associated Parkinson disease.
Tsika E; Moore DJ
Small GTPases; 2013; 4(3):164-70. PubMed ID: 24025585
[TBL] [Abstract][Full Text] [Related]
15. Leucine-rich repeat kinase 2: relevance to Parkinson's disease.
Guo L; Wang W; Chen SG
Int J Biochem Cell Biol; 2006; 38(9):1469-75. PubMed ID: 16600664
[TBL] [Abstract][Full Text] [Related]
16. Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Gilsbach BK; Ho FY; Vetter IR; van Haastert PJ; Wittinghofer A; Kortholt A
Proc Natl Acad Sci U S A; 2012 Jun; 109(26):10322-7. PubMed ID: 22689969
[TBL] [Abstract][Full Text] [Related]
17. The GTPase function of LRRK2.
Taymans JM
Biochem Soc Trans; 2012 Oct; 40(5):1063-9. PubMed ID: 22988866
[TBL] [Abstract][Full Text] [Related]
18. Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants.
Li X; Tan YC; Poulose S; Olanow CW; Huang XY; Yue Z
J Neurochem; 2007 Oct; 103(1):238-47. PubMed ID: 17623048
[TBL] [Abstract][Full Text] [Related]
19. LRRK2 autophosphorylation enhances its GTPase activity.
Liu Z; Mobley JA; DeLucas LJ; Kahn RA; West AB
FASEB J; 2016 Jan; 30(1):336-47. PubMed ID: 26396237
[TBL] [Abstract][Full Text] [Related]
20. Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2.
Vancraenenbroeck R; Lobbestael E; Weeks SD; Strelkov SV; Baekelandt V; Taymans JM; De Maeyer M
Biochim Biophys Acta; 2012 Mar; 1824(3):450-60. PubMed ID: 22251894
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
