321 related articles for article (PubMed ID: 16969077)
1. CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.
Appleman LJ; Chernova I; Li L; Boussiotis VA
Cell Cycle; 2006 Sep; 5(18):2123-9. PubMed ID: 16969077
[TBL] [Abstract][Full Text] [Related]
2. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
Bornstein G; Ganoth D; Hershko A
Proc Natl Acad Sci U S A; 2006 Aug; 103(31):11515-20. PubMed ID: 16861300
[TBL] [Abstract][Full Text] [Related]
3. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
Bashir T; Dorrello NV; Amador V; Guardavaccaro D; Pagano M
Nature; 2004 Mar; 428(6979):190-3. PubMed ID: 15014502
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
[TBL] [Abstract][Full Text] [Related]
5. Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase.
Hao B; Zheng N; Schulman BA; Wu G; Miller JJ; Pagano M; Pavletich NP
Mol Cell; 2005 Oct; 20(1):9-19. PubMed ID: 16209941
[TBL] [Abstract][Full Text] [Related]
6. Activation of ubiquitin ligase SCF(Skp2) by Cks1: insights from hydrogen exchange mass spectrometry.
Yao ZP; Zhou M; Kelly SE; Seeliger MA; Robinson CV; Itzhaki LS
J Mol Biol; 2006 Oct; 363(3):673-86. PubMed ID: 16979657
[TBL] [Abstract][Full Text] [Related]
7. Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.
Old JB; Kratzat S; Hoellein A; Graf S; Nilsson JA; Nilsson L; Nakayama KI; Peschel C; Cleveland JL; Keller UB
Mol Cancer Res; 2010 Mar; 8(3):353-62. PubMed ID: 20197382
[TBL] [Abstract][Full Text] [Related]
8. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
Huang KT; Pavlides SC; Lecanda J; Blank SV; Mittal KR; Gold LI
PLoS One; 2012; 7(9):e46072. PubMed ID: 23029392
[TBL] [Abstract][Full Text] [Related]
9. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1.
Ungermannova D; Lee J; Zhang G; Dallmann HG; McHenry CS; Liu X
J Biomol Screen; 2013 Sep; 18(8):910-20. PubMed ID: 23589337
[TBL] [Abstract][Full Text] [Related]
10. Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
Nakayama K; Nagahama H; Minamishima YA; Matsumoto M; Nakamichi I; Kitagawa K; Shirane M; Tsunematsu R; Tsukiyama T; Ishida N; Kitagawa M; Nakayama K; Hatakeyama S
EMBO J; 2000 May; 19(9):2069-81. PubMed ID: 10790373
[TBL] [Abstract][Full Text] [Related]
11. Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase.
Xu S; Abbasian M; Patel P; Jensen-Pergakes K; Lombardo CR; Cathers BE; Xie W; Mercurio F; Pagano M; Giegel D; Cox S
J Biol Chem; 2007 May; 282(21):15462-70. PubMed ID: 17409098
[TBL] [Abstract][Full Text] [Related]
12. Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Rowland RJ; Heath R; Maskell D; Thompson RF; Ranson NA; Blaza JN; Endicott JA; Noble MEM; Salamina M
Sci Rep; 2023 Jul; 13(1):10718. PubMed ID: 37400515
[TBL] [Abstract][Full Text] [Related]
13. Epidermal growth factor upregulates Skp2/Cks1 and p27(kip1) in human extrahepatic cholangiocarcinoma cells.
Kim JY; Kim HJ; Park JH; Park DI; Cho YK; Sohn CI; Jeon WK; Kim BI; Kim DH; Chae SW; Sohn JH
World J Gastroenterol; 2014 Jan; 20(3):755-73. PubMed ID: 24574749
[TBL] [Abstract][Full Text] [Related]
14. Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression.
O'Hagan RC; Ohh M; David G; de Alboran IM; Alt FW; Kaelin WG; DePinho RA
Genes Dev; 2000 Sep; 14(17):2185-91. PubMed ID: 10970882
[TBL] [Abstract][Full Text] [Related]
15. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
Uehara N; Yoshizawa K; Tsubura A
Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
[TBL] [Abstract][Full Text] [Related]
16. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells.
Bhatt KV; Hu R; Spofford LS; Aplin AE
Oncogene; 2007 Feb; 26(7):1056-66. PubMed ID: 16924241
[TBL] [Abstract][Full Text] [Related]
17. Triggering ubiquitination of a CDK inhibitor at origins of DNA replication.
Furstenthal L; Swanson C; Kaiser BK; Eldridge AG; Jackson PK
Nat Cell Biol; 2001 Aug; 3(8):715-22. PubMed ID: 11483956
[TBL] [Abstract][Full Text] [Related]
18. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).
Mamillapalli R; Gavrilova N; Mihaylova VT; Tsvetkov LM; Wu H; Zhang H; Sun H
Curr Biol; 2001 Feb; 11(4):263-7. PubMed ID: 11250155
[TBL] [Abstract][Full Text] [Related]
19. The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27.
Ganoth D; Bornstein G; Ko TK; Larsen B; Tyers M; Pagano M; Hershko A
Nat Cell Biol; 2001 Mar; 3(3):321-4. PubMed ID: 11231585
[TBL] [Abstract][Full Text] [Related]
20. Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src.
Cen B; Li H; Weinstein IB
J Biol Chem; 2009 Feb; 284(8):5265-76. PubMed ID: 19112177
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
