These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 16969499)

  • 1. Missense mutations of BRCA1 gene affect the binding with p53 both in vitro and in vivo.
    Quaresima B; Faniello MC; Baudi F; Crugliano T; Di Sanzo M; Cuda G; Costanzo F; Venuta S
    Oncol Rep; 2006 Oct; 16(4):811-5. PubMed ID: 16969499
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of cancer-linked BRCA1-BRCT missense variants and their interaction with phosphoprotein targets.
    Drikos I; Nounesis G; Vorgias CE
    Proteins; 2009 Nov; 77(2):464-76. PubMed ID: 19452558
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel domain of BRCA1 interacts with p53 in breast cancer cells.
    Buck M
    Cancer Lett; 2008 Sep; 268(1):137-45. PubMed ID: 18501503
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter.
    Chai YL; Cui J; Shao N; Shyam E; Reddy P; Rao VN
    Oncogene; 1999 Jan; 18(1):263-8. PubMed ID: 9926942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition.
    Mirkovic N; Marti-Renom MA; Weber BL; Sali A; Monteiro AN
    Cancer Res; 2004 Jun; 64(11):3790-7. PubMed ID: 15172985
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A yeast recombination assay to characterize human BRCA1 missense variants of unknown pathological significance.
    Caligo MA; Bonatti F; Guidugli L; Aretini P; Galli A
    Hum Mutat; 2009 Jan; 30(1):123-33. PubMed ID: 18680205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.
    Quaresima B; Romeo F; Faniello MC; Di Sanzo M; Liu CG; Lavecchia A; Taccioli C; Gaudio E; Baudi F; Trapasso F; Croce CM; Cuda G; Costanzo F
    Clin Cancer Res; 2008 Nov; 14(21):6797-803. PubMed ID: 18980973
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cancer-related mutations in BRCA1-BRCT cause long-range structural changes in protein-protein binding sites: a molecular dynamics study.
    Gough CA; Gojobori T; Imanishi T
    Proteins; 2007 Jan; 66(1):69-86. PubMed ID: 17063491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.
    Magnard C; Bachelier R; Vincent A; Jaquinod M; Kieffer S; Lenoir GM; Venezia ND
    Oncogene; 2002 Oct; 21(44):6729-39. PubMed ID: 12360400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effects of BRCA1 missense variants V1804D and M1628T on transcriptional activity.
    Ostrow KL; McGuire V; Whittemore AS; DiCioccio RA
    Cancer Genet Cytogenet; 2004 Sep; 153(2):177-80. PubMed ID: 15350310
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition.
    Pavlicek A; Noskov VN; Kouprina N; Barrett JC; Jurka J; Larionov V
    Hum Mol Genet; 2004 Nov; 13(22):2737-51. PubMed ID: 15385441
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Missense mutations in the BRCT domain of BRCA-1 from high-risk women frequently perturb strongly hydrophobic amino acids conserved among mammals.
    Figge MA; Blankenship L
    Cancer Epidemiol Biomarkers Prev; 2004 Jun; 13(6):1037-41. PubMed ID: 15184261
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance.
    Chenevix-Trench G; Healey S; Lakhani S; Waring P; Cummings M; Brinkworth R; Deffenbaugh AM; Burbidge LA; Pruss D; Judkins T; Scholl T; Bekessy A; Marsh A; Lovelock P; Wong M; Tesoriero A; Renard H; Southey M; Hopper JL; Yannoukakos K; Brown M; Easton D; Tavtigian SV; Goldgar D; Spurdle AB;
    Cancer Res; 2006 Feb; 66(4):2019-27. PubMed ID: 16489001
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1.
    Pyrpassopoulos S; Ladopoulou A; Vlassi M; Papanikolau Y; Vorgias CE; Yannoukakos D; Nounesis G
    Biophys Chem; 2005 Apr; 114(1):1-12. PubMed ID: 15792855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterisation of gene expression profiles of yeast cells expressing BRCA1 missense variants.
    Di Cecco L; Melissari E; Mariotti V; Iofrida C; Galli A; Guidugli L; Lombardi G; Caligo MA; Iacopetti P; Pellegrini S
    Eur J Cancer; 2009 Aug; 45(12):2187-96. PubMed ID: 19493677
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.
    Holstege H; Joosse SA; van Oostrom CT; Nederlof PM; de Vries A; Jonkers J
    Cancer Res; 2009 Apr; 69(8):3625-33. PubMed ID: 19336573
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BRCA1 physically associates with p53 and stimulates its transcriptional activity.
    Zhang H; Somasundaram K; Peng Y; Tian H; Zhang H; Bi D; Weber BL; El-Deiry WS
    Oncogene; 1998 Apr; 16(13):1713-21. PubMed ID: 9582019
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BRCA1 carries tumor suppressor activity distinct from that of p53 and p21.
    Randrianarison V; Marot D; Foray N; Cabannes J; Méret V; Connault E; Vitrat N; Opolon P; Perricaudet M; Feunteun J
    Cancer Gene Ther; 2001 Oct; 8(10):759-70. PubMed ID: 11687899
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional and physical interactions between BRCA1 and p53 in transcriptional regulation of the IGF-IR gene.
    Abramovitch S; Werner H
    Horm Metab Res; 2003; 35(11-12):758-62. PubMed ID: 14710355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms.
    Lu M; Arrick BA
    Oncogene; 2000 Dec; 19(54):6351-60. PubMed ID: 11175350
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.