224 related articles for article (PubMed ID: 16973622)
1. Clioquinol, a Cu(II)/Zn(II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1alpha, leading to expression of vascular endothelial growth factor and erythropoietin in normoxic cells.
Choi SM; Choi KO; Park YK; Cho H; Yang EG; Park H
J Biol Chem; 2006 Nov; 281(45):34056-63. PubMed ID: 16973622
[TBL] [Abstract][Full Text] [Related]
2. The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1alpha protein in normoxic cells.
Choi SM; Choi KO; Lee N; Oh M; Park H
Biochem Biophys Res Commun; 2006 May; 343(4):1002-8. PubMed ID: 16579968
[TBL] [Abstract][Full Text] [Related]
3. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
[TBL] [Abstract][Full Text] [Related]
4. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
5. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
[TBL] [Abstract][Full Text] [Related]
6. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
Jung DB; Lee HJ; Jeong SJ; Lee HJ; Lee EO; Kim YC; Ahn KS; Chen CY; Kim SH
Biol Pharm Bull; 2011; 34(6):850-5. PubMed ID: 21628883
[TBL] [Abstract][Full Text] [Related]
7. Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.
Pagé EL; Chan DA; Giaccia AJ; Levine M; Richard DE
Mol Biol Cell; 2008 Jan; 19(1):86-94. PubMed ID: 17942596
[TBL] [Abstract][Full Text] [Related]
8. Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.
Lee HY; Lee T; Lee N; Yang EG; Lee C; Lee J; Moon EY; Ha J; Park H
Carcinogenesis; 2011 May; 32(5):703-12. PubMed ID: 21335603
[TBL] [Abstract][Full Text] [Related]
9. Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
Martin F; Linden T; Katschinski DM; Oehme F; Flamme I; Mukhopadhyay CK; Eckhardt K; Tröger J; Barth S; Camenisch G; Wenger RH
Blood; 2005 Jun; 105(12):4613-9. PubMed ID: 15741220
[TBL] [Abstract][Full Text] [Related]
10. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
11. Effects of clioquinol analogues on the hypoxia-inducible factor pathway and intracelullar mobilization of metal ions.
Kim SY; Lee MJ; Kim JW; Na YR; Lee HY; Cho H; Lee KB; Lee YM; Lee C; Park H; Yang EG
Biol Pharm Bull; 2012; 35(12):2160-9. PubMed ID: 23207768
[TBL] [Abstract][Full Text] [Related]
12. Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.
Koshikawa N; Takenaga K
Cancer Res; 2005 Dec; 65(24):11622-30. PubMed ID: 16357173
[TBL] [Abstract][Full Text] [Related]
13. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
[TBL] [Abstract][Full Text] [Related]
14. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
Foxler DE; Bridge KS; James V; Webb TM; Mee M; Wong SC; Feng Y; Constantin-Teodosiu D; Petursdottir TE; Bjornsson J; Ingvarsson S; Ratcliffe PJ; Longmore GD; Sharp TV
Nat Cell Biol; 2012 Jan; 14(2):201-8. PubMed ID: 22286099
[TBL] [Abstract][Full Text] [Related]
15. Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
Flashman E; Davies SL; Yeoh KK; Schofield CJ
Biochem J; 2010 Mar; 427(1):135-42. PubMed ID: 20055761
[TBL] [Abstract][Full Text] [Related]
16. Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1.
To KK; Huang LE
J Biol Chem; 2005 Nov; 280(45):38102-7. PubMed ID: 16157596
[TBL] [Abstract][Full Text] [Related]
17. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
18. Regulation of gene expression by the hypoxia-inducible factors.
Fedele AO; Whitelaw ML; Peet DJ
Mol Interv; 2002 Jul; 2(4):229-43. PubMed ID: 14993394
[TBL] [Abstract][Full Text] [Related]
19. Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
Lee SH; Che X; Jeong JH; Choi JY; Lee YJ; Lee YH; Bae SC; Lee YM
J Biol Chem; 2012 Apr; 287(18):14760-71. PubMed ID: 22351759
[TBL] [Abstract][Full Text] [Related]
20. Hypoxia-inducible factor 1 (HIF-1) pathway.
Semenza GL
Sci STKE; 2007 Oct; 2007(407):cm8. PubMed ID: 17925579
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]