BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 16983334)

  • 1. Cyclooxygenase inhibitors modulate the p53/HDM2 pathway and enhance chemotherapy-induced apoptosis in neuroblastoma.
    Lau L; Hansford LM; Cheng LS; Hang M; Baruchel S; Kaplan DR; Irwin MS
    Oncogene; 2007 Mar; 26(13):1920-31. PubMed ID: 16983334
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Requirement for HDM2 activity in the rapid degradation of p53 in neuroblastoma.
    Isaacs JS; Saito S; Neckers LM
    J Biol Chem; 2001 May; 276(21):18497-506. PubMed ID: 11279110
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma.
    Lu J; Guan S; Zhao Y; Yu Y; Wang Y; Shi Y; Mao X; Yang KL; Sun W; Xu X; Yi JS; Yang T; Yang J; Nuchtern JG
    Oncotarget; 2016 Dec; 7(50):82757-82769. PubMed ID: 27764791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability.
    D'Arcy P; Maruwge W; Ryan BA; Brodin B
    Mol Cancer Res; 2008 Jan; 6(1):127-38. PubMed ID: 18234968
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MDM2 mediated nuclear exclusion of p53 attenuates etoposide-induced apoptosis in neuroblastoma cells.
    Rodriguez-Lopez AM; Xenaki D; Eden TO; Hickman JA; Chresta CM
    Mol Pharmacol; 2001 Jan; 59(1):135-43. PubMed ID: 11125034
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.
    Lau LM; Nugent JK; Zhao X; Irwin MS
    Oncogene; 2008 Feb; 27(7):997-1003. PubMed ID: 17700533
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells.
    Elison JR; Cobrinik D; Claros N; Abramson DH; Lee TC
    Arch Ophthalmol; 2006 Sep; 124(9):1269-75. PubMed ID: 16966622
    [TBL] [Abstract][Full Text] [Related]  

  • 8. USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis.
    Fan YH; Cheng J; Vasudevan SA; Dou J; Zhang H; Patel RH; Ma IT; Rojas Y; Zhao Y; Yu Y; Zhang H; Shohet JM; Nuchtern JG; Kim ES; Yang J
    Cell Death Dis; 2013 Oct; 4(10):e867. PubMed ID: 24136231
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen.
    Michaelis M; Agha B; Rothweiler F; Löschmann N; Voges Y; Mittelbronn M; Starzetz T; Harter PN; Abhari BA; Fulda S; Westermann F; Riecken K; Spek S; Langer K; Wiese M; Dirks WG; Zehner R; Cinatl J; Wass MN; Cinatl J
    Sci Rep; 2015 Feb; 5():8202. PubMed ID: 25644037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HDM2 impairs Noxa transcription and affects apoptotic cell death in a p53/p73-dependent manner in neuroblastoma.
    Shi Y; Takenobu H; Kurata K; Yamaguchi Y; Yanagisawa R; Ohira M; Koike K; Nakagawara A; Jiang LL; Kamijo T
    Eur J Cancer; 2010 Aug; 46(12):2324-34. PubMed ID: 20591651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein kinase C epsilon confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53.
    Shankar E; Sivaprasad U; Basu A
    Oncogene; 2008 Jun; 27(28):3957-66. PubMed ID: 18317451
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
    Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
    FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.
    Linares LK; Hengstermann A; Ciechanover A; Müller S; Scheffner M
    Proc Natl Acad Sci U S A; 2003 Oct; 100(21):12009-14. PubMed ID: 14507994
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of cyclooxygenase-2 in colorectal adenocarcinoma is associated with p53 accumulation and hdm2 overexpression.
    Cressey R; Pimpa S; Tontrong W; Watananupong O; Leartprasertsuke N
    Cancer Lett; 2006 Feb; 233(2):232-9. PubMed ID: 15921850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tirapazamine cytotoxicity for neuroblastoma is p53 dependent.
    Yang B; Reynolds CP
    Clin Cancer Res; 2005 Apr; 11(7):2774-80. PubMed ID: 15814660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage.
    Cai X; Liu X
    Proc Natl Acad Sci U S A; 2008 Nov; 105(44):16958-63. PubMed ID: 18952844
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma.
    Liontas A; Yeger H
    Anticancer Res; 2004; 24(2B):987-98. PubMed ID: 15161054
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.
    Gama V; Gomez JA; Mayo LD; Jackson MW; Danielpour D; Song K; Haas AL; Laughlin MJ; Matsuyama S
    Cell Death Differ; 2009 May; 16(5):758-69. PubMed ID: 19247369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage.
    Joseph TW; Zaika A; Moll UM
    FASEB J; 2003 Sep; 17(12):1622-30. PubMed ID: 12958168
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts.
    Latonen L; Taya Y; Laiho M
    Oncogene; 2001 Oct; 20(46):6784-93. PubMed ID: 11709713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.