BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 16985068)

  • 1. Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis.
    Blum R; Jacob-Hirsch J; Rechavi G; Kloog Y
    Mol Cancer Ther; 2006 Sep; 5(9):2337-47. PubMed ID: 16985068
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition.
    Charette N; De Saeger C; Lannoy V; Horsmans Y; Leclercq I; Stärkel P
    Mol Cancer; 2010 Sep; 9():256. PubMed ID: 20860815
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death.
    Blum R; Jacob-Hirsch J; Amariglio N; Rechavi G; Kloog Y
    Cancer Res; 2005 Feb; 65(3):999-1006. PubMed ID: 15705901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells.
    Erlich S; Tal-Or P; Liebling R; Blum R; Karunagaran D; Kloog Y; Pinkas-Kramarski R
    Biochem Pharmacol; 2006 Aug; 72(4):427-36. PubMed ID: 16780807
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphatidylinositol 3-kinase inhibition down-regulates survivin and facilitates TRAIL-mediated apoptosis in neuroblastomas.
    Kim S; Kang J; Qiao J; Thomas RP; Evers BM; Chung DH
    J Pediatr Surg; 2004 Apr; 39(4):516-21. PubMed ID: 15065019
    [TBL] [Abstract][Full Text] [Related]  

  • 6. E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition.
    Blum R; Nakdimon I; Goldberg L; Elkon R; Shamir R; Rechavi G; Kloog Y
    Int J Cancer; 2006 Aug; 119(3):527-38. PubMed ID: 16496386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disruption of the inhibitor of apoptosis protein survivin sensitizes Bcr-abl-positive cells to STI571-induced apoptosis.
    Wang Z; Sampath J; Fukuda S; Pelus LM
    Cancer Res; 2005 Sep; 65(18):8224-32. PubMed ID: 16166298
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The inhibition of human mesangial cell proliferation by S-trans, trans-farnesylthiosalicylic acid.
    Khwaja A; Sharpe CC; Noor M; Kloog Y; Hendry BM
    Kidney Int; 2005 Aug; 68(2):474-86. PubMed ID: 16014024
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activated H-Ras regulates hematopoietic cell survival by modulating Survivin.
    Fukuda S; Pelus LM
    Biochem Biophys Res Commun; 2004 Oct; 323(2):636-44. PubMed ID: 15369798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).
    Blum R; Elkon R; Yaari S; Zundelevich A; Jacob-Hirsch J; Rechavi G; Shamir R; Kloog Y
    Cancer Res; 2007 Apr; 67(7):3320-8. PubMed ID: 17409441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance.
    Gana-Weisz M; Halaschek-Wiener J; Jansen B; Elad G; Haklai R; Kloog Y
    Clin Cancer Res; 2002 Feb; 8(2):555-65. PubMed ID: 11839677
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phenotypic reversion of invasive neurofibromin-deficient schwannoma by FTS: Ras inhibition reduces BMP4/Erk/Smad signaling.
    Barkan B; Kloog Y; Ehrlich M
    Mol Cancer Ther; 2011 Aug; 10(8):1317-26. PubMed ID: 21632464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death.
    Schmukler E; Wolfson E; Haklai R; Elad-Sfadia G; Kloog Y; Pinkas-Kramarski R
    Oncotarget; 2014 Jan; 5(1):173-84. PubMed ID: 24368422
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc.
    Yaari-Stark S; Shaked M; Nevo-Caspi Y; Jacob-Hircsh J; Shamir R; Rechavi G; Kloog Y
    Int J Cancer; 2010 May; 126(10):2268-81. PubMed ID: 19998334
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells.
    Kang DW; Choi CH; Park JY; Kang SK; Kim YK
    Neurochem Res; 2008 Mar; 33(3):551-61. PubMed ID: 17940898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ras inhibition enhances autophagy, which partially protects cells from death.
    Schmukler E; Grinboim E; Schokoroy S; Amir A; Wolfson E; Kloog Y; Pinkas-Kramarski R
    Oncotarget; 2013 Jan; 4(1):145-55. PubMed ID: 23370967
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives.
    Wu L; Pang Y; Qin G; Xi G; Wu S; Wang X; Chen T
    PLoS One; 2017; 12(2):e0171840. PubMed ID: 28182780
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Molecular mechanism of anti-apoptotic action of survivin in NCI-H446 lung cancer cells].
    Chen Y; Li W; Zhou JH; Li DM; Xia XM; Huang LN; Li BQ
    Zhonghua Zhong Liu Za Zhi; 2006 Jun; 28(6):413-7. PubMed ID: 17152484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAS Promotes Proliferation and Resistances to Apoptosis in Meningioma.
    Jiang C; Song T; Li J; Ao F; Gong X; Lu Y; Zhang C; Chen L; Liu Y; He H; Huang O
    Mol Neurobiol; 2017 Jan; 54(1):779-787. PubMed ID: 27021020
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells.
    Zvibel I; Bar-Zohar D; Kloog Y; Oren R; Reif S
    Dig Dis Sci; 2008 Apr; 53(4):1048-53. PubMed ID: 17934818
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.