BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 16986263)

  • 1. Application of predictive biosimulation within pharmaceutical clinical development: examples of significance for translational medicine and clinical trial design.
    Kansal AR; Trimmer J
    Syst Biol (Stevenage); 2005 Dec; 152(4):214-20. PubMed ID: 16986263
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development.
    Krishna R; Schaefer HG; Bjerrum OJ
    Eur J Pharm Sci; 2007 May; 31(1):62-7. PubMed ID: 17408933
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Extrapolation of preclinical data into clinical reality translational science.
    Singer T
    Ernst Schering Res Found Workshop; 2007; (59):1-5. PubMed ID: 17117711
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predictive biosimulation and virtual patients in pharmaceutical R and D.
    Bangs A
    Stud Health Technol Inform; 2005; 111():37-42. PubMed ID: 15718695
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biosimulation software is changing research.
    Ho RL; Bartsell LT
    Biotechnol Annu Rev; 2004; 10():297-302. PubMed ID: 15504712
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico prediction of clinical efficacy.
    Michelson S; Sehgal A; Friedrich C
    Curr Opin Biotechnol; 2006 Dec; 17(6):666-70. PubMed ID: 17046236
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging technologies for prediction of drug candidate efficacy in the preclinical pipeline.
    Menshykau D
    Drug Discov Today; 2017 Nov; 22(11):1598-1603. PubMed ID: 28545837
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Failure and success in modern drug discovery: guiding principles in the establishment of high probability of success drug discovery organizations.
    Rishton GM
    Med Chem; 2005 Sep; 1(5):519-27. PubMed ID: 16787336
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulatory acceptance of animal models of disease to support clinical trials of medicines and advanced therapy medicinal products.
    Cavagnaro J; Silva Lima B
    Eur J Pharmacol; 2015 Jul; 759():51-62. PubMed ID: 25814257
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape.
    Schuck E; Bohnert T; Chakravarty A; Damian-Iordache V; Gibson C; Hsu CP; Heimbach T; Krishnatry AS; Liederer BM; Lin J; Maurer T; Mettetal JT; Mudra DR; Nijsen MJ; Raybon J; Schroeder P; Schuck V; Suryawanshi S; Su Y; Trapa P; Tsai A; Vakilynejad M; Wang S; Wong H
    AAPS J; 2015 Mar; 17(2):462-73. PubMed ID: 25630504
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and evaluation of molecular properties related to preclinical optimization and clinical fate.
    Blake JF
    Med Chem; 2005 Nov; 1(6):649-55. PubMed ID: 16787349
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Assessing the impact of predictive biosimulation on drug discovery and development.
    Michelson S
    J Bioinform Comput Biol; 2003 Apr; 1(1):169-77. PubMed ID: 15290786
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alternative strategies in drug development: clinical pharmacological aspects.
    Kuhlmann J
    Int J Clin Pharmacol Ther; 1999 Dec; 37(12):575-83. PubMed ID: 10599949
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Translational medicine 2006.
    Persiani S
    IDrugs; 2006 Apr; 9(4):253-5. PubMed ID: 16596476
    [No Abstract]   [Full Text] [Related]  

  • 15. Stroke drug development: usually, but not always, animal models.
    Donnan GA; Davis SM
    Stroke; 2005 Oct; 36(10):2326. PubMed ID: 16141427
    [No Abstract]   [Full Text] [Related]  

  • 16. Use of animal models has not contributed to development of acute stroke therapies: pro.
    Kaste M
    Stroke; 2005 Oct; 36(10):2323-4. PubMed ID: 16141431
    [No Abstract]   [Full Text] [Related]  

  • 17. Use of animal models has not contributed to development of acute stroke therapies: con.
    Fisher M; Tatlisumak T
    Stroke; 2005 Oct; 36(10):2324-5. PubMed ID: 16141429
    [No Abstract]   [Full Text] [Related]  

  • 18. Approaches for predicting human pharmacokinetics using interspecies pharmacokinetic scaling.
    Kang HE; Lee MG
    Arch Pharm Res; 2011 Nov; 34(11):1779-88. PubMed ID: 22139680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Microfluidics for drug discovery and development: from target selection to product lifecycle management.
    Kang L; Chung BG; Langer R; Khademhosseini A
    Drug Discov Today; 2008 Jan; 13(1-2):1-13. PubMed ID: 18190858
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Translational biomarkers: from preclinical to clinical a report of 2009 AAPS/ACCP Biomarker Workshop.
    Bai JP; Bell R; Buckman S; Burckart GJ; Eichler HG; Fang KC; Goodsaid FM; Jusko WJ; Lesko LL; Meibohm B; Patterson SD; Puig O; Smerage JB; Snider BJ; Wagner JA; Wang J; Walton MK; Weiner R
    AAPS J; 2011 Jun; 13(2):274-83. PubMed ID: 21448748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.