BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

858 related articles for article (PubMed ID: 16990547)

  • 1. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
    Meyer-Luehmann M; Coomaraswamy J; Bolmont T; Kaeser S; Schaefer C; Kilger E; Neuenschwander A; Abramowski D; Frey P; Jaton AL; Vigouret JM; Paganetti P; Walsh DM; Mathews PM; Ghiso J; Staufenbiel M; Walker LC; Jucker M
    Science; 2006 Sep; 313(5794):1781-4. PubMed ID: 16990547
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling Alzheimer's disease and other proteopathies in vivo: is seeding the key?
    Walker LC; Bian F; Callahan MJ; Lipinski WJ; Durham RA; LeVine H
    Amino Acids; 2002; 23(1-3):87-93. PubMed ID: 12373522
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetics and amyloid plaque targeting ability of a novel peptide-based magnetic resonance contrast agent in wild-type and Alzheimer's disease transgenic mice.
    Kandimalla KK; Wengenack TM; Curran GL; Gilles EJ; Poduslo JF
    J Pharmacol Exp Ther; 2007 Aug; 322(2):541-9. PubMed ID: 17505020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease.
    Wyss-Coray T; Masliah E; Mallory M; McConlogue L; Johnson-Wood K; Lin C; Mucke L
    Nature; 1997 Oct; 389(6651):603-6. PubMed ID: 9335500
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis.
    Dedeoglu A; Cormier K; Payton S; Tseitlin KA; Kremsky JN; Lai L; Li X; Moir RD; Tanzi RE; Bush AI; Kowall NW; Rogers JT; Huang X
    Exp Gerontol; 2004; 39(11-12):1641-9. PubMed ID: 15582280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The effect of amyloidosis-beta and ageing on proliferation of neuronal progenitor cells in APP-transgenic mouse hippocampus and in culture.
    Kolecki R; Lafauci G; Rubenstein R; Mazur-Kolecka B; Kaczmarski W; Frackowiak J
    Acta Neuropathol; 2008 Oct; 116(4):419-24. PubMed ID: 18483741
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
    Imbimbo BP; Del Giudice E; Colavito D; D'Arrigo A; Dalle Carbonare M; Villetti G; Facchinetti F; Volta R; Pietrini V; Baroc MF; Serneels L; De Strooper B; Leon A
    J Pharmacol Exp Ther; 2007 Dec; 323(3):822-30. PubMed ID: 17895400
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.
    Philipson O; Hammarström P; Nilsson KP; Portelius E; Olofsson T; Ingelsson M; Hyman BT; Blennow K; Lannfelt L; Kalimo H; Nilsson LN
    Neurobiol Aging; 2009 Sep; 30(9):1393-405. PubMed ID: 18192084
    [TBL] [Abstract][Full Text] [Related]  

  • 9. One-year longitudinal evaluation of sensorimotor functions in APP751SL transgenic mice.
    Le Cudennec C; Faure A; Ly M; Delatour B
    Genes Brain Behav; 2008 Feb; 7 Suppl 1():83-91. PubMed ID: 18184372
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic and pharmacological evidence of intraneuronal Abeta accumulation in APP transgenic mice.
    Philipson O; Lannfelt L; Nilsson LN
    FEBS Lett; 2009 Sep; 583(18):3021-6. PubMed ID: 19683527
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
    J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peripheral and central biodistribution of (111)In-labeled anti-beta-amyloid autoantibodies in a transgenic mouse model of Alzheimer's disease.
    Bacher M; Depboylu C; Du Y; Noelker C; Oertel WH; Behr T; Henriksen G; Behe M; Dodel R
    Neurosci Lett; 2009 Jan; 449(3):240-5. PubMed ID: 18786612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice.
    Lahiri DK; Chen D; Maloney B; Holloway HW; Yu QS; Utsuki T; Giordano T; Sambamurti K; Greig NH
    J Pharmacol Exp Ther; 2007 Jan; 320(1):386-96. PubMed ID: 17003227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R; Koistinaho J; Malm T; Sikkilä H; Vainio S; Koistinaho M
    Glia; 2008 Jan; 56(2):154-63. PubMed ID: 18004725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels.
    Rakover I; Arbel M; Solomon B
    Neurodegener Dis; 2007; 4(5):392-402. PubMed ID: 17536186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [What causes Abeta amyloidosis in the brain?].
    Matsubara E; Yanagisawa K
    No To Shinkei; 2005 Oct; 57(10):829-38. PubMed ID: 16277228
    [No Abstract]   [Full Text] [Related]  

  • 17. Beneficial effects of quetiapine in a transgenic mouse model of Alzheimer's disease.
    He J; Luo H; Yan B; Yu Y; Wang H; Wei Z; Zhang Y; Xu H; Tempier A; Li X; Li XM
    Neurobiol Aging; 2009 Aug; 30(8):1205-16. PubMed ID: 18079026
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis.
    Lee EB; Leng LZ; Lee VM; Trojanowski JQ
    FEBS Lett; 2005 May; 579(12):2564-8. PubMed ID: 15862291
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.
    Abramowski D; Wiederhold KH; Furrer U; Jaton AL; Neuenschwander A; Runser MJ; Danner S; Reichwald J; Ammaturo D; Staab D; Stoeckli M; Rueeger H; Neumann U; Staufenbiel M
    J Pharmacol Exp Ther; 2008 Nov; 327(2):411-24. PubMed ID: 18687920
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduced serum level of antibodies against amyloid beta peptide is associated with aging in Tg2576 mice.
    Sohn JH; So JO; Kim H; Nam EJ; Ha HJ; Kim YH; Mook-Jung I
    Biochem Biophys Res Commun; 2007 Sep; 361(3):800-4. PubMed ID: 17678618
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 43.