BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 16996476)

  • 21. Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats.
    Lehto SG; Tamir R; Deng H; Klionsky L; Kuang R; Le A; Lee D; Louis JC; Magal E; Manning BH; Rubino J; Surapaneni S; Tamayo N; Wang T; Wang J; Wang J; Wang W; Youngblood B; Zhang M; Zhu D; Norman MH; Gavva NR
    J Pharmacol Exp Ther; 2008 Jul; 326(1):218-29. PubMed ID: 18420600
    [TBL] [Abstract][Full Text] [Related]  

  • 22. (R)-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) blocks polymodal activation of transient receptor potential vanilloid 1 receptors in vitro and heat-evoked firing of spinal dorsal horn neurons in vivo.
    Surowy CS; Neelands TR; Bianchi BR; McGaraughty S; El Kouhen R; Han P; Chu KL; McDonald HA; Vos M; Niforatos W; Bayburt EK; Gomtsyan A; Lee CH; Honore P; Sullivan JP; Jarvis MF; Faltynek CR
    J Pharmacol Exp Ther; 2008 Sep; 326(3):879-88. PubMed ID: 18515644
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia.
    Kanai Y; Hara T; Imai A; Sakakibara A
    J Pharm Pharmacol; 2007 May; 59(5):733-8. PubMed ID: 17524240
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A novel role for the TRPV1 channel in UV-induced matrix metalloproteinase (MMP)-1 expression in HaCaT cells.
    Lee YM; Kim YK; Kim KH; Park SJ; Kim SJ; Chung JH
    J Cell Physiol; 2009 Jun; 219(3):766-75. PubMed ID: 19206161
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design and synthesis of peripherally restricted transient receptor potential vanilloid 1 (TRPV1) antagonists.
    Tamayo N; Liao H; Stec MM; Wang X; Chakrabarti P; Retz D; Doherty EM; Surapaneni S; Tamir R; Bannon AW; Gavva NR; Norman MH
    J Med Chem; 2008 May; 51(9):2744-57. PubMed ID: 18386885
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A potential role for the vanilloid receptor TRPV1 in the therapeutic effect of curcumin in dinitrobenzene sulphonic acid-induced colitis in mice.
    Martelli L; Ragazzi E; di Mario F; Martelli M; Castagliuolo I; Dal Maschio M; Palù G; Maschietto M; Scorzeto M; Vassanelli S; Brun P
    Neurogastroenterol Motil; 2007 Aug; 19(8):668-74. PubMed ID: 17640182
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Bone cancer increases transient receptor potential vanilloid subfamily 1 expression within distinct subpopulations of dorsal root ganglion neurons.
    Niiyama Y; Kawamata T; Yamamoto J; Omote K; Namiki A
    Neuroscience; 2007 Aug; 148(2):560-72. PubMed ID: 17656027
    [TBL] [Abstract][Full Text] [Related]  

  • 28. TRPV1: a therapeutic target for novel analgesic drugs?
    Szallasi A; Cruz F; Geppetti P
    Trends Mol Med; 2006 Nov; 12(11):545-54. PubMed ID: 16996800
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1.
    Gavva NR; Tamir R; Klionsky L; Norman MH; Louis JC; Wild KD; Treanor JJ
    Mol Pharmacol; 2005 Dec; 68(6):1524-33. PubMed ID: 16135784
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Effects of the transient receptor potential vanilloid 1 antagonist A-425619 on body temperature and thermoregulation in the rat.
    Mills C; McMackin M; Jaffe R; Yu J; Zininberg E; Slee D; Gogas K; Bradbury M
    Neuroscience; 2008 Sep; 156(1):165-74. PubMed ID: 18706981
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Transient receptor potential vanilloid type 1 receptor regulates glutamatergic synaptic inputs to the spinothalamic tract neurons of the spinal cord deep dorsal horn.
    Kim H; Cui L; Kim J; Kim SJ
    Neuroscience; 2009 May; 160(2):508-16. PubMed ID: 19236908
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis.
    Ghosh AK; Basu S
    Cancer Lett; 2010 Jan; 287(2):142-9. PubMed ID: 19570606
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks.
    Wong GY; Gavva NR
    Brain Res Rev; 2009 Apr; 60(1):267-77. PubMed ID: 19150372
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Involvement of afferent neurons in the pathogenesis of endotoxin-induced ileus in mice: role of CGRP and TRPV1 receptors.
    De Winter BY; Bredenoord AJ; Van Nassauw L; De Man JG; De Schepper HU; Timmermans JP; Pelckmans PA
    Eur J Pharmacol; 2009 Aug; 615(1-3):177-84. PubMed ID: 19445917
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.
    Culshaw AJ; Bevan S; Christiansen M; Copp P; Davis A; Davis C; Dyson A; Dziadulewicz EK; Edwards L; Eggelte H; Fox A; Gentry C; Groarke A; Hallett A; Hart TW; Hughes GA; Knights S; Kotsonis P; Lee W; Lyothier I; McBryde A; McIntyre P; Paloumbis G; Panesar M; Patel S; Seiler MP; Yaqoob M; Zimmermann K
    J Med Chem; 2006 Jan; 49(2):471-4. PubMed ID: 16420034
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Role of TRPV1 and TRPA1 in visceral hypersensitivity to colorectal distension during experimental colitis in rats.
    Vermeulen W; De Man JG; De Schepper HU; Bult H; Moreels TG; Pelckmans PA; De Winter BY
    Eur J Pharmacol; 2013 Jan; 698(1-3):404-12. PubMed ID: 23099257
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The analgesic drug, tramadol, acts as an agonist of the transient receptor potential vanilloid-1.
    Marincsák R; Tóth BI; Czifra G; Szabó T; Kovács L; Bíró T
    Anesth Analg; 2008 Jun; 106(6):1890-6. PubMed ID: 18499628
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats.
    McGaraughty S; Chu KL; Brown BS; Zhu CZ; Zhong C; Joshi SK; Honore P; Faltynek CR; Jarvis MF
    J Neurophysiol; 2008 Dec; 100(6):3158-66. PubMed ID: 18829846
    [TBL] [Abstract][Full Text] [Related]  

  • 39. SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-alpha production through the activation of capsaicin-sensitive afferent neurons mediated via transient receptor potential vanilloid 1 in vivo.
    Murai M; Tsuji F; Nose M; Seki I; Oki K; Setoguchi C; Suhara H; Sasano M; Aono H
    Eur J Pharmacol; 2008 Jul; 588(2-3):309-15. PubMed ID: 18508045
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A polyclonal antibody to the prepore loop of transient receptor potential vanilloid type 1 blocks channel activation.
    Klionsky L; Tamir R; Holzinger B; Bi X; Talvenheimo J; Kim H; Martin F; Louis JC; Treanor JJ; Gavva NR
    J Pharmacol Exp Ther; 2006 Oct; 319(1):192-8. PubMed ID: 16844842
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.