BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 1699678)

  • 1. Covalent binding studies on the 14C-labeled antitumor compound 2,5-bis(1-aziridinyl)-1,4-benzoquinone. Involvement of semiquinone radical in binding to DNA, and binding to proteins and bacterial macromolecules in situ.
    Lusthof KJ; De Mol NJ; Janssen LH; Egberink RJ; Verboom W; Reinhoudt DN
    Chem Biol Interact; 1990; 76(2):193-209. PubMed ID: 1699678
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interactions between potential anti-tumour 2,5-bis(1-aziridinyl)-1,4-benzoquinone derivatives and glutathione: reductive activation, conjugation and DNA damage.
    Lusthof KJ; de Mol NJ; Janssen LH; Prins B; Verboom W; Reinhoudt DN
    Anticancer Drug Des; 1990 Aug; 5(3):283-90. PubMed ID: 2205226
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA alkylation and formation of DNA interstrand cross-links by potential antitumour 2,5-bis(1-aziridinyl)-1,4-benzoquinones.
    Lusthof KJ; De Mol NJ; Janssen LH; Verboom W; Reinhoudt DN
    Chem Biol Interact; 1989; 70(3-4):249-62. PubMed ID: 2663197
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism(s) of bioreductive activation. The example of diaziquone (AZQ).
    Gutierrez PL
    Free Radic Biol Med; 1989; 6(4):405-45. PubMed ID: 2651223
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reductive activation of potential antitumor bis(aziridinyl)benzoquinones by xanthine oxidase: competition between oxygen reduction and quinone reduction.
    Lusthof KJ; Richter W; de Mol NJ; Janssen LH; Verboom W; Reinhoudt DN
    Arch Biochem Biophys; 1990 Feb; 277(1):137-42. PubMed ID: 2154955
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thiol oxidation coupled to DT-diaphorase-catalysed reduction of diaziquone. Reductive and oxidative pathways of diaziquone semiquinone modulated by glutathione and superoxide dismutase.
    OrdoƱez ID; Cadenas E
    Biochem J; 1992 Sep; 286 ( Pt 2)(Pt 2):481-90. PubMed ID: 1530580
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alkylation of DNA by the new anticancer agent 3,6-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone (AZQ).
    King CL; Wong SK; Loo TL
    Eur J Cancer Clin Oncol; 1984 Feb; 20(2):261-4. PubMed ID: 6538490
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Redox cycling of potential antitumor aziridinyl quinones.
    Lusthof KJ; de Mol NJ; Richter W; Janssen LH; Butler J; Hoey BM; Verboom W; Reinhoudt DN
    Free Radic Biol Med; 1992 Dec; 13(6):599-608. PubMed ID: 1334033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism for the reductive activation of diaziquone.
    Mossoba MM; Alizadeh M; Gutierrez PL
    J Pharm Sci; 1985 Dec; 74(12):1249-54. PubMed ID: 4087189
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sigmatropic reactions of the aziridinyl semiquinone species. Why aziridinyl benzoquinones are metabolically more stable than aziridinyl indoloquinones.
    Xing C; Skibo EB
    Biochemistry; 2000 Sep; 39(35):10770-80. PubMed ID: 10978162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The chemical reduction of diaziquone: products and free radical intermediates.
    Gutierrez PL; Balachandran Nayar MS; Nardino R; Callery PS
    Chem Biol Interact; 1987; 64(1-2):23-37. PubMed ID: 2826025
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sonochemically induced covalent binding of calf thymus DNA by aziridinylquinones.
    Alegria AE; Sanchez-Cruz P; Lopez-Colon D
    Radiat Res; 2005 Oct; 164(4 Pt 1):446-52. PubMed ID: 16187747
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alteration in DNA cross-linking and sequence selectivity of a series of aziridinylbenzoquinones after enzymatic reduction by DT-diaphorase.
    Lee CS; Hartley JA; Berardini MD; Butler J; Siegel D; Ross D; Gibson NW
    Biochemistry; 1992 Mar; 31(11):3019-25. PubMed ID: 1372518
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The alkylation of DNA in vitro by 2,5-bis(2-hydroxyethylamino)-3,6-diaziridinyl-1,4-benzoquinone (BZQ)--I.
    Butler J; Hoey BM; Ward TH
    Biochem Pharmacol; 1989 Mar; 38(6):923-7. PubMed ID: 2930592
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reductive activation of diaziquone and possible involvement of free radicals and the hydroquinone dianion.
    Gutierrez PL; Biswal S; Nardino R; Biswal N
    Cancer Res; 1986 Nov; 46(11):5779-85. PubMed ID: 3019536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA-DNA interstrand cross-linking by 2,5-bis(1-aziridinyl)-3,6-bis(carbethoxyamino)-1,4-benzoquinone: covalent structure of the dG-to-dG cross-links in calf thymus DNA and a synthetic DNA duplex.
    Alley SC; Hopkins PB
    Chem Res Toxicol; 1994; 7(5):666-72. PubMed ID: 7841346
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical activation of AZQ [3,6-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone] to its free radical species.
    Gutierrez PL; Friedman RD; Bachur NR
    Cancer Treat Rep; 1982 Feb; 66(2):339-42. PubMed ID: 6275990
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanisms of DNA strand breakage and interstrand cross-linking by diaziridinylbenzoquinone (diaziquone) in isolated nuclei from human cells.
    Szmigiero L; Kohn KW
    Cancer Res; 1984 Oct; 44(10):4453-7. PubMed ID: 6467205
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemistry and DNA alkylation reactions of aziridinyl quinones: development of an efficient alkylating agent of the phosphate backbone.
    Skibo EB; Xing C
    Biochemistry; 1998 Oct; 37(43):15199-213. PubMed ID: 9790684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Free radicals in quinone containing antitumor agents. The nature of the diaziquone (3,6,-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone) free radical.
    Gutierrez PL; Bachur NR
    Biochim Biophys Acta; 1983 Jul; 758(1):37-41. PubMed ID: 6305426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.