257 related articles for article (PubMed ID: 16998589)
1. Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease.
Nikolskaia OV; de A Lima AP; Kim YV; Lonsdale-Eccles JD; Fukuma T; Scharfstein J; Grab DJ
J Clin Invest; 2006 Oct; 116(10):2739-47. PubMed ID: 16998589
[TBL] [Abstract][Full Text] [Related]
2. African trypanosome interactions with an in vitro model of the human blood-brain barrier.
Grab DJ; Nikolskaia O; Kim YV; Lonsdale-Eccles JD; Ito S; Hara T; Fukuma T; Nyarko E; Kim KJ; Stins MF; Delannoy MJ; Rodgers J; Kim KS
J Parasitol; 2004 Oct; 90(5):970-9. PubMed ID: 15562595
[TBL] [Abstract][Full Text] [Related]
3. Improved trypanocidal activities of cathepsin L inhibitors.
Nkemgu NJ; Grande R; Hansell E; McKerrow JH; Caffrey CR; Steverding D
Int J Antimicrob Agents; 2003 Aug; 22(2):155-9. PubMed ID: 12927956
[TBL] [Abstract][Full Text] [Related]
4. Traversal of human and animal trypanosomes across the blood-brain barrier.
Grab DJ; Kennedy PG
J Neurovirol; 2008 Oct; 14(5):344-51. PubMed ID: 19016378
[TBL] [Abstract][Full Text] [Related]
5. The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis.
Ettari R; Previti S; Tamborini L; Cullia G; Grasso S; Zappalà M
Mini Rev Med Chem; 2016; 16(17):1374-1391. PubMed ID: 27156518
[TBL] [Abstract][Full Text] [Related]
6. A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei.
Mackey ZB; O'Brien TC; Greenbaum DC; Blank RB; McKerrow JH
J Biol Chem; 2004 Nov; 279(46):48426-33. PubMed ID: 15326171
[TBL] [Abstract][Full Text] [Related]
7. Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei.
Yang PY; Wang M; He CY; Yao SQ
Chem Commun (Camb); 2012 Jan; 48(6):835-7. PubMed ID: 22124229
[TBL] [Abstract][Full Text] [Related]
8. RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model.
Abdulla MH; O'Brien T; Mackey ZB; Sajid M; Grab DJ; McKerrow JH
PLoS Negl Trop Dis; 2008 Sep; 2(9):e298. PubMed ID: 18820745
[TBL] [Abstract][Full Text] [Related]
9. Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells.
Grab DJ; Garcia-Garcia JC; Nikolskaia OV; Kim YV; Brown A; Pardo CA; Zhang Y; Becker KG; Wilson BA; de A Lima AP; Scharfstein J; Dumler JS
PLoS Negl Trop Dis; 2009 Jul; 3(7):e479. PubMed ID: 19621073
[TBL] [Abstract][Full Text] [Related]
10. Entry of Trypanosoma brucei gambiense into microvascular endothelial cells of the human blood-brain barrier.
Nikolskaia OV; Kim YV; Kovbasnjuk O; Kim KJ; Grab DJ
Int J Parasitol; 2006 May; 36(5):513-9. PubMed ID: 16620822
[TBL] [Abstract][Full Text] [Related]
11. Evaluation of trypanocidal activity of combinations of anti-sleeping sickness drugs with cysteine protease inhibitors.
Steverding D
Exp Parasitol; 2015; 151-152():28-33. PubMed ID: 25662707
[TBL] [Abstract][Full Text] [Related]
12. Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei.
Troeberg L; Chen X; Flaherty TM; Morty RE; Cheng M; Hua H; Springer C; McKerrow JH; Kenyon GL; Lonsdale-Eccles JD; Coetzer TH; Cohen FE
Mol Med; 2000 Aug; 6(8):660-9. PubMed ID: 11055585
[TBL] [Abstract][Full Text] [Related]
13. Identification of non-peptidic cysteine reactive fragments as inhibitors of cysteine protease rhodesain.
McShan D; Kathman S; Lowe B; Xu Z; Zhan J; Statsyuk A; Ogungbe IV
Bioorg Med Chem Lett; 2015 Oct; 25(20):4509-12. PubMed ID: 26342866
[TBL] [Abstract][Full Text] [Related]
14. Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense.
Caffrey CR; Hansell E; Lucas KD; Brinen LS; Alvarez Hernandez A; Cheng J; Gwaltney SL; Roush WR; Stierhof YD; Bogyo M; Steverding D; McKerrow JH
Mol Biochem Parasitol; 2001 Nov; 118(1):61-73. PubMed ID: 11704274
[TBL] [Abstract][Full Text] [Related]
15. Should the enzyme name 'rhodesain' be discontinued?
Steverding D; Caffrey CR
Mol Biochem Parasitol; 2021 Sep; 245():111395. PubMed ID: 34246720
[TBL] [Abstract][Full Text] [Related]
16. A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome.
Capewell P; Cooper A; Clucas C; Weir W; Macleod A
Parasitology; 2015 Feb; 142 Suppl 1(Suppl 1):S108-19. PubMed ID: 25656360
[TBL] [Abstract][Full Text] [Related]
17. Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.
Mallari JP; Shelat A; Kosinski A; Caffrey CR; Connelly M; Zhu F; McKerrow JH; Guy RK
Bioorg Med Chem Lett; 2008 May; 18(9):2883-5. PubMed ID: 18420405
[TBL] [Abstract][Full Text] [Related]
18. Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies.
Nakamura K; Fujioka S; Fukumoto S; Inoue N; Sakamoto K; Hirata H; Kido Y; Yabu Y; Suzuki T; Watanabe Y; Saimoto H; Akiyama H; Kita K
Parasitol Int; 2010 Dec; 59(4):560-4. PubMed ID: 20688188
[TBL] [Abstract][Full Text] [Related]
19. Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei.
Troeberg L; Morty RE; Pike RN; Lonsdale-Eccles JD; Palmer JT; McKerrow JH; Coetzer TH
Exp Parasitol; 1999 Apr; 91(4):349-55. PubMed ID: 10092479
[TBL] [Abstract][Full Text] [Related]
20. Trypanosoma brucei: Inhibition of cathepsin L is sufficient to kill bloodstream forms.
Steverding D; Rushworth SA; Florea BI; Overkleeft HS
Mol Biochem Parasitol; 2020 Jan; 235():111246. PubMed ID: 31743688
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
