BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 17001313)

  • 1. Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells.
    Iwamaru A; Kondo Y; Iwado E; Aoki H; Fujiwara K; Yokoyama T; Mills GB; Kondo S
    Oncogene; 2007 Mar; 26(13):1840-51. PubMed ID: 17001313
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.
    Ronellenfitsch MW; Brucker DP; Burger MC; Wolking S; Tritschler F; Rieger J; Wick W; Weller M; Steinbach JP
    Brain; 2009 Jun; 132(Pt 6):1509-22. PubMed ID: 19416948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways.
    Aoki H; Takada Y; Kondo S; Sawaya R; Aggarwal BB; Kondo Y
    Mol Pharmacol; 2007 Jul; 72(1):29-39. PubMed ID: 17395690
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells.
    Edinger AL; Linardic CM; Chiang GG; Thompson CB; Abraham RT
    Cancer Res; 2003 Dec; 63(23):8451-60. PubMed ID: 14679009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.
    Takeuchi H; Kondo Y; Fujiwara K; Kanzawa T; Aoki H; Mills GB; Kondo S
    Cancer Res; 2005 Apr; 65(8):3336-46. PubMed ID: 15833867
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced radiation damage of tumor vasculature by mTOR inhibitors.
    Shinohara ET; Cao C; Niermann K; Mu Y; Zeng F; Hallahan DE; Lu B
    Oncogene; 2005 Aug; 24(35):5414-22. PubMed ID: 15940265
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions.
    Kaper F; Dornhoefer N; Giaccia AJ
    Cancer Res; 2006 Feb; 66(3):1561-9. PubMed ID: 16452213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells.
    Paglin S; Lee NY; Nakar C; Fitzgerald M; Plotkin J; Deuel B; Hackett N; McMahill M; Sphicas E; Lampen N; Yahalom J
    Cancer Res; 2005 Dec; 65(23):11061-70. PubMed ID: 16322256
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus.
    Ito H; Aoki H; Kühnel F; Kondo Y; Kubicka S; Wirth T; Iwado E; Iwamaru A; Fujiwara K; Hess KR; Lang FF; Sawaya R; Kondo S
    J Natl Cancer Inst; 2006 May; 98(9):625-36. PubMed ID: 16670388
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors.
    Moreno A; Akcakanat A; Munsell MF; Soni A; Yao JC; Meric-Bernstam F
    Endocr Relat Cancer; 2008 Mar; 15(1):257-66. PubMed ID: 18310292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway.
    Sobolewska A; Gajewska M; Zarzyńska J; Gajkowska B; Motyl T
    Eur J Cell Biol; 2009 Feb; 88(2):117-30. PubMed ID: 19013662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR.
    Hou G; Xue L; Lu Z; Fan T; Tian F; Xue Y
    Cancer Lett; 2007 Aug; 253(2):236-48. PubMed ID: 17360108
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells.
    Tiwari M; Bajpai VK; Sahasrabuddhe AA; Kumar A; Sinha RA; Behari S; Godbole MM
    Carcinogenesis; 2008 Mar; 29(3):600-9. PubMed ID: 18174255
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergistic effect of rapamycin and cisplatin in endometrial cancer cells.
    Bae-Jump VL; Zhou C; Boggess JF; Gehrig PA
    Cancer; 2009 Sep; 115(17):3887-96. PubMed ID: 19484784
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.
    Gorshtein A; Rubinfeld H; Kendler E; Theodoropoulou M; Cerovac V; Stalla GK; Cohen ZR; Hadani M; Shimon I
    Endocr Relat Cancer; 2009 Sep; 16(3):1017-27. PubMed ID: 19509067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective clearance of macrophages in atherosclerotic plaques by autophagy.
    Verheye S; Martinet W; Kockx MM; Knaapen MW; Salu K; Timmermans JP; Ellis JT; Kilpatrick DL; De Meyer GR
    J Am Coll Cardiol; 2007 Feb; 49(6):706-15. PubMed ID: 17291937
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Akt inhibitor shows anticancer and radiosensitizing effects in malignant glioma cells by inducing autophagy.
    Fujiwara K; Iwado E; Mills GB; Sawaya R; Kondo S; Kondo Y
    Int J Oncol; 2007 Oct; 31(4):753-60. PubMed ID: 17786305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.
    Frost P; Shi Y; Hoang B; Lichtenstein A
    Oncogene; 2007 Apr; 26(16):2255-62. PubMed ID: 17016437
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
    Wang Y; Zhao Q; Ma S; Yang F; Gong Y; Ke C
    IUBMB Life; 2007 Nov; 59(11):717-21. PubMed ID: 17968710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients.
    Hickerson RP; Leake D; Pho LN; Leachman SA; Kaspar RL
    J Dermatol Sci; 2009 Nov; 56(2):82-8. PubMed ID: 19699613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.