BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 17004325)

  • 1. Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.
    Ewan LC; Jopling HM; Jia H; Mittar S; Bagherzadeh A; Howell GJ; Walker JH; Zachary IC; Ponnambalam S
    Traffic; 2006 Sep; 7(9):1270-82. PubMed ID: 17004325
    [TBL] [Abstract][Full Text] [Related]  

  • 2. VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis.
    Bruns AF; Bao L; Walker JH; Ponnambalam S
    Biochem Soc Trans; 2009 Dec; 37(Pt 6):1193-7. PubMed ID: 19909245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.
    Bruns AF; Herbert SP; Odell AF; Jopling HM; Hooper NM; Zachary IC; Walker JH; Ponnambalam S
    Traffic; 2010 Jan; 11(1):161-74. PubMed ID: 19883397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling.
    Jopling HM; Howell GJ; Gamper N; Ponnambalam S
    Biochem Biophys Res Commun; 2011 Jul; 410(2):170-6. PubMed ID: 21539813
    [TBL] [Abstract][Full Text] [Related]  

  • 5. VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8.
    Smith GA; Fearnley GW; Abdul-Zani I; Wheatcroft SB; Tomlinson DC; Harrison MA; Ponnambalam S
    Traffic; 2016 Jan; 17(1):53-65. PubMed ID: 26459808
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Indolinones and anilinophthalazines differentially target VEGF-A- and basic fibroblast growth factor-mediated responses in primary human endothelial cells.
    Latham AM; Bruns AF; Kankanala J; Johnson AP; Fishwick CW; Homer-Vanniasinkam S; Ponnambalam S
    Br J Pharmacol; 2012 Jan; 165(1):245-59. PubMed ID: 21699503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling.
    Farhan MA; Azad AK; Touret N; Murray AG
    Arterioscler Thromb Vasc Biol; 2017 Dec; 37(12):2301-2310. PubMed ID: 29051140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive Endocytosis of VEGFR2 Protects the Receptor against Shedding.
    Basagiannis D; Christoforidis S
    J Biol Chem; 2016 Aug; 291(32):16892-903. PubMed ID: 27298320
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling.
    Kofler N; Corti F; Rivera-Molina F; Deng Y; Toomre D; Simons M
    J Biol Chem; 2018 Mar; 293(13):4805-4817. PubMed ID: 29425100
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Essential role for endocytosis in the growth factor-stimulated activation of ERK1/2 in endothelial cells.
    Gourlaouen M; Welti JC; Vasudev NS; Reynolds AR
    J Biol Chem; 2013 Mar; 288(11):7467-7480. PubMed ID: 23341459
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PEST motif serine and tyrosine phosphorylation controls vascular endothelial growth factor receptor 2 stability and downregulation.
    Meyer RD; Srinivasan S; Singh AJ; Mahoney JE; Gharahassanlou KR; Rahimi N
    Mol Cell Biol; 2011 May; 31(10):2010-25. PubMed ID: 21402774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2.
    Zhang Z; Neiva KG; Lingen MW; Ellis LM; Nör JE
    Cell Death Differ; 2010 Mar; 17(3):499-512. PubMed ID: 19834490
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF.
    Endo A; Fukuhara S; Masuda M; Ohmori T; Mochizuki N
    J Recept Signal Transduct Res; 2003; 23(2-3):239-54. PubMed ID: 14626450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment.
    Gampel A; Moss L; Jones MC; Brunton V; Norman JC; Mellor H
    Blood; 2006 Oct; 108(8):2624-31. PubMed ID: 16638931
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP2.
    Cano I; Wild M; Gupta U; Chaudhary S; Ng YSE; Saint-Geniez M; D'Amore PA; Hu Z
    Cell Commun Signal; 2024 Apr; 22(1):225. PubMed ID: 38605348
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.
    Bruns AF; Yuldasheva N; Latham AM; Bao L; Pellet-Many C; Frankel P; Stephen SL; Howell GJ; Wheatcroft SB; Kearney MT; Zachary IC; Ponnambalam S
    PLoS One; 2012; 7(11):e48539. PubMed ID: 23139789
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Noonan Syndrome Gene
    Sewduth RN; Pandolfi S; Steklov M; Sheryazdanova A; Zhao P; Criem N; Baietti MF; Lechat B; Quarck R; Impens F; Sablina AA
    Circ Res; 2020 May; 126(10):1379-1393. PubMed ID: 32175818
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells.
    Duval M; Bédard-Goulet S; Delisle C; Gratton JP
    J Biol Chem; 2003 May; 278(22):20091-7. PubMed ID: 12649282
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis.
    Ikeda S; Ushio-Fukai M; Zuo L; Tojo T; Dikalov S; Patrushev NA; Alexander RW
    Circ Res; 2005 Mar; 96(4):467-75. PubMed ID: 15692085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells.
    Nakamura Y; Patrushev N; Inomata H; Mehta D; Urao N; Kim HW; Razvi M; Kini V; Mahadev K; Goldstein BJ; McKinney R; Fukai T; Ushio-Fukai M
    Circ Res; 2008 May; 102(10):1182-91. PubMed ID: 18451337
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.