BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 17005552)

  • 1. Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase.
    Yakovleva L; Lai J; Kool ET; Shuman S
    J Biol Chem; 2006 Nov; 281(47):35914-21. PubMed ID: 17005552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Individual nucleotide bases, not base pairs, are critical for triggering site-specific DNA cleavage by vaccinia topoisomerase.
    Tian L; Sayer JM; Jerina DM; Shuman S
    J Biol Chem; 2004 Sep; 279(38):39718-26. PubMed ID: 15252055
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications.
    Yakovleva L; Tian L; Sayer JM; Kalena GP; Kroth H; Jerina DM; Shuman S
    J Biol Chem; 2003 Oct; 278(43):42170-7. PubMed ID: 12909623
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical and traditional mutagenesis of vaccinia DNA topoisomerase provides insights to cleavage site recognition and transesterification chemistry.
    Yakovleva L; Chen S; Hecht SM; Shuman S
    J Biol Chem; 2008 Jun; 283(23):16093-103. PubMed ID: 18367446
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB.
    Tian L; Claeboe CD; Hecht SM; Shuman S
    Structure; 2004 Jan; 12(1):31-40. PubMed ID: 14725763
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutational analysis of 39 residues of vaccinia DNA topoisomerase identifies Lys-220, Arg-223, and Asn-228 as important for covalent catalysis.
    Cheng C; Wang LK; Sekiguchi J; Shuman S
    J Biol Chem; 1997 Mar; 272(13):8263-9. PubMed ID: 9079646
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase.
    Yakovleva L; Handy CJ; Sayer JM; Pirrung M; Jerina DM; Shuman S
    J Biol Chem; 2004 May; 279(22):23335-42. PubMed ID: 15044474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of 2'-5' phosphodiesters on DNA transesterification by vaccinia topoisomerase.
    Krogh BO; Claeboe CD; Hecht SM; Shuman S
    J Biol Chem; 2001 Jun; 276(24):20907-12. PubMed ID: 11399773
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Site-specific DNA transesterification by vaccinia topoisomerase: role of specific phosphates and nucleosides.
    Cheng C; Shuman S
    Biochemistry; 1999 Dec; 38(50):16599-612. PubMed ID: 10600122
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167.
    Wittschieben J; Shuman S
    Nucleic Acids Res; 1997 Aug; 25(15):3001-8. PubMed ID: 9224599
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histidine 265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes.
    Petersen BO; Shuman S
    J Biol Chem; 1997 Feb; 272(7):3891-6. PubMed ID: 9020090
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III.
    Yakovleva L; Handy CJ; Yagi H; Sayer JM; Jerina DM; Shuman S
    Biochemistry; 2006 Jun; 45(24):7644-53. PubMed ID: 16768460
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage.
    Wang LK; Wittschieben J; Shuman S
    Biochemistry; 1997 Jul; 36(26):7944-50. PubMed ID: 9201940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A catalytic domain of eukaryotic DNA topoisomerase I.
    Cheng C; Shuman S
    J Biol Chem; 1998 May; 273(19):11589-95. PubMed ID: 9565576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vaccinia topoisomerase mutants illuminate conformational changes during closure of the protein clamp and assembly of a functional active site.
    Krogh BO; Shuman S
    J Biol Chem; 2001 Sep; 276(39):36091-9. PubMed ID: 11441004
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase.
    Stivers JT; Jagadeesh GJ; Nawrot B; Stec WJ; Shuman S
    Biochemistry; 2000 May; 39(18):5561-72. PubMed ID: 10820030
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of DNA Binding by the Isolated N-Terminal Domain of Vaccinia Virus DNA Topoisomerase IB.
    Reed B; Yakovleva L; Shuman S; Ghose R
    Biochemistry; 2017 Jul; 56(26):3307-3317. PubMed ID: 28570045
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Covalent DNA binding by vaccinia topoisomerase results in unpairing of the thymine base 5' of the scissile bond.
    Sekiguchi J; Shuman S
    J Biol Chem; 1996 Aug; 271(32):19436-42. PubMed ID: 8702632
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specific DNA cleavage and binding by vaccinia virus DNA topoisomerase I.
    Shuman S; Prescott J
    J Biol Chem; 1990 Oct; 265(29):17826-36. PubMed ID: 2170398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA strand transfer catalyzed by vaccinia topoisomerase: peroxidolysis and hydroxylaminolysis of the covalent protein-DNA intermediate.
    Krogh BO; Shuman S
    Biochemistry; 2000 May; 39(21):6422-32. PubMed ID: 10828956
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.