201 related articles for article (PubMed ID: 17012232)
21. Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation.
Eimer WA; Vassar R
Mol Neurodegener; 2013 Jan; 8():2. PubMed ID: 23316765
[TBL] [Abstract][Full Text] [Related]
22. Preferential deposition of amyloid beta protein (Abeta) in the form Abeta40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E E4 allele.
Mann DM; Iwatsubo T; Pickering-Brown SM; Owen F; Saido TC; Perry RH
Neurosci Lett; 1997 Jan; 221(2-3):81-4. PubMed ID: 9121705
[TBL] [Abstract][Full Text] [Related]
23. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
Brecht WJ; Harris FM; Chang S; Tesseur I; Yu GQ; Xu Q; Dee Fish J; Wyss-Coray T; Buttini M; Mucke L; Mahley RW; Huang Y
J Neurosci; 2004 Mar; 24(10):2527-34. PubMed ID: 15014128
[TBL] [Abstract][Full Text] [Related]
24. The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer's Disease and Parkinson's Disease and Models of Mild Cognitive Impairment.
Hwang J; Estick CM; Ikonne US; Butler D; Pait MC; Elliott LH; Ruiz S; Smith K; Rentschler KM; Mundell C; Almeida MF; Stumbling Bear N; Locklear JP; Abumohsen Y; Ivey CM; Farizatto KLG; Bahr BA
Int J Mol Sci; 2019 Sep; 20(18):. PubMed ID: 31505809
[TBL] [Abstract][Full Text] [Related]
25. Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels.
Schedin-Weiss S; Inoue M; Hromadkova L; Teranishi Y; Yamamoto NG; Wiehager B; Bogdanovic N; Winblad B; Sandebring-Matton A; Frykman S; Tjernberg LO
Alzheimers Res Ther; 2017 Aug; 9(1):57. PubMed ID: 28764767
[TBL] [Abstract][Full Text] [Related]
26. Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease.
Nagele RG; D'Andrea MR; Anderson WJ; Wang HY
Neuroscience; 2002; 110(2):199-211. PubMed ID: 11958863
[TBL] [Abstract][Full Text] [Related]
27. Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.
Fryer JD; Taylor JW; DeMattos RB; Bales KR; Paul SM; Parsadanian M; Holtzman DM
J Neurosci; 2003 Aug; 23(21):7889-96. PubMed ID: 12944519
[TBL] [Abstract][Full Text] [Related]
28. Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid.
Chen G; Chen KS; Kobayashi D; Barbour R; Motter R; Games D; Martin SJ; Morris RG
J Neurosci; 2007 Mar; 27(10):2654-62. PubMed ID: 17344403
[TBL] [Abstract][Full Text] [Related]
29. beta-amyloid (Abeta)42(43), abeta42, abeta40 and apoE immunostaining of plaques in fatal head injury.
Horsburgh K; Cole GM; Yang F; Savage MJ; Greenberg BD; Gentleman SM; Graham DI; Nicoll JA
Neuropathol Appl Neurobiol; 2000 Apr; 26(2):124-32. PubMed ID: 10840275
[TBL] [Abstract][Full Text] [Related]
30. Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice.
Chan ES; Chen C; Cole GM; Wong BS
Sci Rep; 2015 Sep; 5():13842. PubMed ID: 26346625
[TBL] [Abstract][Full Text] [Related]
31. Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration.
Ji ZS; Müllendorff K; Cheng IH; Miranda RD; Huang Y; Mahley RW
J Biol Chem; 2006 Feb; 281(5):2683-92. PubMed ID: 16298992
[TBL] [Abstract][Full Text] [Related]
32. Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors.
Barucker C; Sommer A; Beckmann G; Eravci M; Harmeier A; Schipke CG; Brockschnieder D; Dyrks T; Althoff V; Fraser PE; Hazrati LN; George-Hyslop PS; Breitner JC; Peters O; Multhaup G
J Alzheimers Dis; 2015; 44(2):613-24. PubMed ID: 25318543
[TBL] [Abstract][Full Text] [Related]
33. Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation.
Manelli AM; Bulfinch LC; Sullivan PM; LaDu MJ
Neurobiol Aging; 2007 Aug; 28(8):1139-47. PubMed ID: 16837105
[TBL] [Abstract][Full Text] [Related]
34. Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.
Kaur G; Pawlik M; Gandy SE; Ehrlich ME; Smiley JF; Levy E
Mol Psychiatry; 2017 Jul; 22(7):981-989. PubMed ID: 27777419
[TBL] [Abstract][Full Text] [Related]
35. Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.
Kawarabayashi T; Shoji M; Younkin LH; Wen-Lang L; Dickson DW; Murakami T; Matsubara E; Abe K; Ashe KH; Younkin SG
J Neurosci; 2004 Apr; 24(15):3801-9. PubMed ID: 15084661
[TBL] [Abstract][Full Text] [Related]
36. Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration.
Kuszczyk MA; Sanchez S; Pankiewicz J; Kim J; Duszczyk M; Guridi M; Asuni AA; Sullivan PM; Holtzman DM; Sadowski MJ
Am J Pathol; 2013 May; 182(5):1750-68. PubMed ID: 23499462
[TBL] [Abstract][Full Text] [Related]
37. LRP and senile plaques in Alzheimer's disease: colocalization with apolipoprotein E and with activated astrocytes.
Arélin K; Kinoshita A; Whelan CM; Irizarry MC; Rebeck GW; Strickland DK; Hyman BT
Brain Res Mol Brain Res; 2002 Jul; 104(1):38-46. PubMed ID: 12117549
[TBL] [Abstract][Full Text] [Related]
38. Membrane localization of beta-amyloid 1-42 in lysosomes: a possible mechanism for lysosome labilization.
Liu RQ; Zhou QH; Ji SR; Zhou Q; Feng D; Wu Y; Sui SF
J Biol Chem; 2010 Jun; 285(26):19986-96. PubMed ID: 20430896
[TBL] [Abstract][Full Text] [Related]
39. Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production.
He X; Cooley K; Chung CH; Dashti N; Tang J
J Neurosci; 2007 Apr; 27(15):4052-60. PubMed ID: 17428983
[TBL] [Abstract][Full Text] [Related]
40. Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
Cam JA; Zerbinatti CV; Li Y; Bu G
J Biol Chem; 2005 Apr; 280(15):15464-70. PubMed ID: 15705569
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
