BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

347 related articles for article (PubMed ID: 17012279)

  • 1. In vitro evolution of single-chain antibodies using mRNA display.
    Fukuda I; Kojoh K; Tabata N; Doi N; Takashima H; Miyamoto-Sato E; Yanagawa H
    Nucleic Acids Res; 2006; 34(19):e127. PubMed ID: 17012279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two-step in vitro antibody affinity maturation enables estradiol-17beta assays with more than 10-fold higher sensitivity.
    Kobayashi N; Oyama H; Kato Y; Goto J; Söderlind E; Borrebaeck CA
    Anal Chem; 2010 Feb; 82(3):1027-38. PubMed ID: 20047279
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selection and affinity maturation of human antibodies against rabies virus from a scFv gene library using ribosome display.
    Zhao XL; Chen WQ; Yang ZH; Li JM; Zhang SJ; Tian LF
    J Biotechnol; 2009 Dec; 144(4):253-8. PubMed ID: 19818816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.
    van den Beucken T; van Neer N; Sablon E; Desmet J; Celis L; Hoogenboom HR; Hufton SE
    J Mol Biol; 2001 Jul; 310(3):591-601. PubMed ID: 11439026
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A.
    Razai A; Garcia-Rodriguez C; Lou J; Geren IN; Forsyth CM; Robles Y; Tsai R; Smith TJ; Smith LA; Siegel RW; Feldhaus M; Marks JD
    J Mol Biol; 2005 Aug; 351(1):158-69. PubMed ID: 16002090
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Improving the affinity of an anti-TNF-alpha scFv by random mutation].
    Wang BA; Chen XS; Wang YX; Qu J; Zhou LJ; Wang Y
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2005 Jul; 21(4):445-8. PubMed ID: 15989787
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anti-estradiol-17beta single-chain Fv fragments: Generation, characterization, gene randomization, and optimized phage display.
    Kobayashi N; Kato Y; Oyama H; Taga S; Niwa T; Sun P; Ohtoyo M; Goto J
    Steroids; 2008 Dec; 73(14):1485-99. PubMed ID: 18824188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site.
    Schier R; McCall A; Adams GP; Marshall KW; Merritt H; Yim M; Crawford RS; Weiner LM; Marks C; Marks JD
    J Mol Biol; 1996 Nov; 263(4):551-67. PubMed ID: 8918938
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
    Finlay WJ; Cunningham O; Lambert MA; Darmanin-Sheehan A; Liu X; Fennell BJ; Mahon CM; Cummins E; Wade JM; O'Sullivan CM; Tan XY; Piche N; Pittman DD; Paulsen J; Tchistiakova L; Kodangattil S; Gill D; Hufton SE
    J Mol Biol; 2009 May; 388(3):541-58. PubMed ID: 19285987
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein.
    Pavoni E; Flego M; Dupuis ML; Barca S; Petronzelli F; Anastasi AM; D'Alessio V; Pelliccia A; Vaccaro P; Monteriù G; Ascione A; De Santis R; Felici F; Cianfriglia M; Minenkova O
    BMC Cancer; 2006 Feb; 6():41. PubMed ID: 16504122
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Production of human single-chain variable fragment (scFv) antibody specific for digoxin by ribosome display.
    Yan XH; Xu ZR
    Indian J Biochem Biophys; 2005 Dec; 42(6):350-7. PubMed ID: 16955735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation and characterization of phage-displayed single chain antibodies recognizing nonreducing terminal mannose residues. 1. A new strategy for generation of anti-carbohydrate antibodies.
    Sakai K; Shimizu Y; Chiba T; Matsumoto-Takasaki A; Kusada Y; Zhang W; Nakata M; Kojima N; Toma K; Takayanagi A; Shimizu N; Fujita-Yamaguchi Y
    Biochemistry; 2007 Jan; 46(1):253-62. PubMed ID: 17198396
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro antibody maturation. Improvement of a high affinity, neutralizing antibody against IL-1 beta.
    Jackson JR; Sathe G; Rosenberg M; Sweet R
    J Immunol; 1995 Apr; 154(7):3310-9. PubMed ID: 7897213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Directed evolution, phage display and combination of evolved mutants: a strategy to recover the neutralization properties of the scFv version of BCF2 a neutralizing monoclonal antibody specific to scorpion toxin Cn2.
    Juárez-González VR; Riaño-Umbarila L; Quintero-Hernández V; Olamendi-Portugal T; Ortiz-León M; Ortíz E; Possani LD; Becerril B
    J Mol Biol; 2005 Mar; 346(5):1287-97. PubMed ID: 15713481
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selection for improved protein stability by phage display.
    Jung S; Honegger A; Plückthun A
    J Mol Biol; 1999 Nov; 294(1):163-80. PubMed ID: 10556036
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Affinity maturation of phage display antibody populations using ribosome display.
    Groves M; Lane S; Douthwaite J; Lowne D; Rees DG; Edwards B; Jackson RH
    J Immunol Methods; 2006 Jun; 313(1-2):129-39. PubMed ID: 16730741
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies.
    Daugherty PS; Chen G; Iverson BL; Georgiou G
    Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2029-34. PubMed ID: 10688877
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation.
    Luginbühl B; Kanyo Z; Jones RM; Fletterick RJ; Prusiner SB; Cohen FE; Williamson RA; Burton DR; Plückthun A
    J Mol Biol; 2006 Oct; 363(1):75-97. PubMed ID: 16962610
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Improving antibody affinity by mimicking somatic hypermutation in vitro.
    Chowdhury PS; Pastan I
    Nat Biotechnol; 1999 Jun; 17(6):568-72. PubMed ID: 10385321
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ligation-based assembly for constructing mouse synthetic scFv libraries by chain shuffling with in vivo-amplified VH and VL fragments.
    Nishi M; Jian N; Yamamoto K; Seto H; Nishida Y; Tonoyama Y; Shimizu N; Nishi Y
    J Immunol Methods; 2014 Oct; 412():53-69. PubMed ID: 25010461
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.