BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 17014917)

  • 1. Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice.
    Schmitt U; Hiemke C; Fahrenholz F; Schroeder A
    Behav Brain Res; 2006 Dec; 175(2):278-84. PubMed ID: 17014917
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.
    Schroeder A; Fahrenholz F; Schmitt U
    J Alzheimers Dis; 2009; 16(2):309-14. PubMed ID: 19221420
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
    Corbett GT; Gonzalez FJ; Pahan K
    Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8445-50. PubMed ID: 26080426
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.
    Tippmann F; Hundt J; Schneider A; Endres K; Fahrenholz F
    FASEB J; 2009 Jun; 23(6):1643-54. PubMed ID: 19144697
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress.
    Clement AB; Hanstein R; Schröder A; Nagel H; Endres K; Fahrenholz F; Behl C
    Neuroscience; 2008 Mar; 152(2):459-68. PubMed ID: 18276079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acitretin, an enhancer of alpha-secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein.
    Holthoewer D; Endres K; Schuck F; Hiemke C; Schmitt U; Fahrenholz F
    Neurodegener Dis; 2012; 10(1-4):224-8. PubMed ID: 22301853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cryptotanshinione upregulates alpha-secretase by activation PI3K pathway in cortical neurons.
    Mei Z; Situ B; Tan X; Zheng S; Zhang F; Yan P; Liu P
    Brain Res; 2010 Aug; 1348():165-73. PubMed ID: 20595051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function.
    Suh J; Choi SH; Romano DM; Gannon MA; Lesinski AN; Kim DY; Tanzi RE
    Neuron; 2013 Oct; 80(2):385-401. PubMed ID: 24055016
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholesterol enhances amyloid β deposition in mouse retina by modulating the activities of Aβ-regulating enzymes in retinal pigment epithelial cells.
    Wang J; Ohno-Matsui K; Morita I
    Biochem Biophys Res Commun; 2012 Aug; 424(4):704-9. PubMed ID: 22796523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.
    Kuhn PH; Wang H; Dislich B; Colombo A; Zeitschel U; Ellwart JW; Kremmer E; Rossner S; Lichtenthaler SF
    EMBO J; 2010 Sep; 29(17):3020-32. PubMed ID: 20676056
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease.
    Reinhardt S; Schuck F; Grösgen S; Riemenschneider M; Hartmann T; Postina R; Grimm M; Endres K
    FASEB J; 2014 Feb; 28(2):978-97. PubMed ID: 24165480
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Upregulation of the alpha-secretase ADAM10--risk or reason for hope?
    Endres K; Fahrenholz F
    FEBS J; 2010 Apr; 277(7):1585-96. PubMed ID: 20136654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome.
    Pasciuto E; Ahmed T; Wahle T; Gardoni F; D'Andrea L; Pacini L; Jacquemont S; Tassone F; Balschun D; Dotti CG; Callaerts-Vegh Z; D'Hooge R; Müller UC; Di Luca M; De Strooper B; Bagni C
    Neuron; 2015 Jul; 87(2):382-98. PubMed ID: 26182420
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.
    Prinzen C; Trümbach D; Wurst W; Endres K; Postina R; Fahrenholz F
    BMC Genomics; 2009 Feb; 10():66. PubMed ID: 19196476
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice.
    Kitaoka K; Shimizu N; Ono K; Chikahisa S; Nakagomi M; Shudo K; Ishimura K; Séi H; Yoshizaki K
    Neuropharmacology; 2013 Sep; 72():58-65. PubMed ID: 23624141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retinoids as a perspective in treatment of Alzheimer's disease.
    Fahrenholz F; Tippmann F; Endres K
    Neurodegener Dis; 2010; 7(1-3):190-2. PubMed ID: 20224284
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increase of disintergin metalloprotease 10 (ADAM10) expression in oral squamous cell carcinoma.
    Ko SY; Lin SC; Wong YK; Liu CJ; Chang KW; Liu TY
    Cancer Lett; 2007 Jan; 245(1-2):33-43. PubMed ID: 16309826
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain.
    Zhuang J; Wei Q; Lin Z; Zhou C
    Gene; 2015 Jan; 555(2):150-8. PubMed ID: 25445276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
    Kim M; Suh J; Romano D; Truong MH; Mullin K; Hooli B; Norton D; Tesco G; Elliott K; Wagner SL; Moir RD; Becker KD; Tanzi RE
    Hum Mol Genet; 2009 Oct; 18(20):3987-96. PubMed ID: 19608551
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.