BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 17016665)

  • 1. Potential of the Akt inhibitor LY294005 to antagonize the efficacy of Cisplatin against HCT116 tumor cells in a DNA mismatch repair-dependent manner.
    Fedier A; Erdmann R; Boulikas T; Fink D
    Int J Oncol; 2006 Nov; 29(5):1303-10. PubMed ID: 17016665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MLH1-deficient tumor cells are resistant to lipoplatin, but retain sensitivity to lipoxal.
    Fedier A; Poyet C; Perucchini D; Boulikas T; Fink D
    Anticancer Drugs; 2006 Mar; 17(3):315-23. PubMed ID: 16520660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Presence of MLH1 protein aggravates the potential of the HSP90 inhibitor radicicol to sensitize tumor cells to cisplatin.
    Fedier A; Stuedli A; Fink D
    Int J Oncol; 2005 Dec; 27(6):1697-705. PubMed ID: 16273226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human colon cancer cells surviving high doses of cisplatin or oxaliplatin in vitro are not defective in DNA mismatch repair proteins.
    Sergent C; Franco N; Chapusot C; Lizard-Nacol S; Isambert N; Correia M; Chauffert B
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):445-52. PubMed ID: 12107548
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of DNA mismatch repair in platinum drug resistance.
    Fink D; Nebel S; Aebi S; Zheng H; Cenni B; Nehmé A; Christen RD; Howell SB
    Cancer Res; 1996 Nov; 56(21):4881-6. PubMed ID: 8895738
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin.
    Lin X; Ramamurthi K; Mishima M; Kondo A; Christen RD; Howell SB
    Cancer Res; 2001 Feb; 61(4):1508-16. PubMed ID: 11245458
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells.
    Nehmé A; Baskaran R; Nebel S; Fink D; Howell SB; Wang JY; Christen RD
    Br J Cancer; 1999 Mar; 79(7-8):1104-10. PubMed ID: 10098743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells.
    Perego P; Gatti L; Caserini C; Supino R; Colangelo D; Leone R; Spinelli S; Farrell N; Zunino F
    J Inorg Biochem; 1999 Oct; 77(1-2):59-64. PubMed ID: 10626355
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resistance to topoisomerase poisons due to loss of DNA mismatch repair.
    Fedier A; Schwarz VA; Walt H; Carpini RD; Haller U; Fink D
    Int J Cancer; 2001 Aug; 93(4):571-6. PubMed ID: 11477562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of H(2)O(2) on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines.
    Chang DK; Goel A; Ricciardiello L; Lee DH; Chang CL; Carethers JM; Boland CR
    Cancer Lett; 2003 Jun; 195(2):243-51. PubMed ID: 12767533
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.
    Tentori L; Muzi A; Dorio AS; Dolci S; Campolo F; Vernole P; Lacal PM; Praz F; Graziani G
    Cancer Chemother Pharmacol; 2013 Jul; 72(1):117-25. PubMed ID: 23636450
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
    Park JM; Huang S; Tougeron D; Sinicrope FA
    PLoS One; 2013; 8(5):e65369. PubMed ID: 23724141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts.
    Vaisman A; Varchenko M; Umar A; Kunkel TA; Risinger JI; Barrett JC; Hamilton TC; Chaney SG
    Cancer Res; 1998 Aug; 58(16):3579-85. PubMed ID: 9721864
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of DNA mismatch repair in acquired resistance to cisplatin.
    Aebi S; Kurdi-Haidar B; Gordon R; Cenni B; Zheng H; Fink D; Christen RD; Boland CR; Koi M; Fishel R; Howell SB
    Cancer Res; 1996 Jul; 56(13):3087-90. PubMed ID: 8674066
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.
    Yan T; Schupp JE; Hwang HS; Wagner MW; Berry SE; Strickfaden S; Veigl ML; Sedwick WD; Boothman DA; Kinsella TJ
    Cancer Res; 2001 Nov; 61(22):8290-7. PubMed ID: 11719462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells.
    Aebi S; Fink D; Gordon R; Kim HK; Zheng H; Fink JL; Howell SB
    Clin Cancer Res; 1997 Oct; 3(10):1763-7. PubMed ID: 9815561
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of drug resistance mediated by loss of mismatch repair by the DNA polymerase inhibitor aphidicolin.
    Moreland NJ; Illand M; Kim YT; Paul J; Brown R
    Cancer Res; 1999 May; 59(9):2102-6. PubMed ID: 10232595
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
    Meyers M; Wagner MW; Hwang HS; Kinsella TJ; Boothman DA
    Cancer Res; 2001 Jul; 61(13):5193-201. PubMed ID: 11431359
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM; Tazzari PL; Tabellini G; Bortul R; Billi AM; Manzoli L; Ruggeri A; Conte R; Cocco L
    Leukemia; 2003 Sep; 17(9):1794-805. PubMed ID: 12970779
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.
    Fedier A; Fowst C; Tursi J; Geroni C; Haller U; Marchini S; Fink D
    Br J Cancer; 2003 Oct; 89(8):1559-65. PubMed ID: 14562032
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.