230 related articles for article (PubMed ID: 17018531)
1. NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols.
Liou HL; Dixit SS; Xu S; Tint GS; Stock AM; Lobel P
J Biol Chem; 2006 Dec; 281(48):36710-23. PubMed ID: 17018531
[TBL] [Abstract][Full Text] [Related]
2. Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein.
Chikh K; Vey S; Simonot C; Vanier MT; Millat G
Mol Genet Metab; 2004 Nov; 83(3):220-30. PubMed ID: 15542393
[TBL] [Abstract][Full Text] [Related]
3. Structural basis of sterol binding by NPC2, a lysosomal protein deficient in Niemann-Pick type C2 disease.
Xu S; Benoff B; Liou HL; Lobel P; Stock AM
J Biol Chem; 2007 Aug; 282(32):23525-31. PubMed ID: 17573352
[TBL] [Abstract][Full Text] [Related]
4. Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport.
McCauliff LA; Xu Z; Li R; Kodukula S; Ko DC; Scott MP; Kahn PC; Storch J
J Biol Chem; 2015 Nov; 290(45):27321-27331. PubMed ID: 26296895
[TBL] [Abstract][Full Text] [Related]
5. NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
Frolov A; Zielinski SE; Crowley JR; Dudley-Rucker N; Schaffer JE; Ory DS
J Biol Chem; 2003 Jul; 278(28):25517-25. PubMed ID: 12719428
[TBL] [Abstract][Full Text] [Related]
6. Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts.
Berzina Z; Solanko LM; Mehadi AS; Jensen MLV; Lund FW; Modzel M; Szomek M; Solanko KA; Dupont A; Nielsen GK; Heegaard CW; Ejsing CS; Wüstner D
Chem Phys Lipids; 2018 Jul; 213():48-61. PubMed ID: 29580834
[TBL] [Abstract][Full Text] [Related]
7. Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease.
Friedland N; Liou HL; Lobel P; Stock AM
Proc Natl Acad Sci U S A; 2003 Mar; 100(5):2512-7. PubMed ID: 12591954
[TBL] [Abstract][Full Text] [Related]
8. Regulation of sterol transport between membranes and NPC2.
Xu Z; Farver W; Kodukula S; Storch J
Biochemistry; 2008 Oct; 47(42):11134-43. PubMed ID: 18823126
[TBL] [Abstract][Full Text] [Related]
9. Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop.
Infante RE; Radhakrishnan A; Abi-Mosleh L; Kinch LN; Wang ML; Grishin NV; Goldstein JL; Brown MS
J Biol Chem; 2008 Jan; 283(2):1064-75. PubMed ID: 17989072
[TBL] [Abstract][Full Text] [Related]
10. Binding and intracellular transport of 25-hydroxycholesterol by Niemann-Pick C2 protein.
Petersen D; Reinholdt P; Szomek M; Hansen SK; Poongavanam V; Dupont A; Heegaard CW; Krishnan K; Fujiwara H; Covey DF; Ory DS; Kongsted J; Wüstner D
Biochim Biophys Acta Biomembr; 2020 Feb; 1862(2):183063. PubMed ID: 31521631
[TBL] [Abstract][Full Text] [Related]
11. Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease.
Nielsen GK; Dagnaes-Hansen F; Holm IE; Meaney S; Symula D; Andersen NT; Heegaard CW
PLoS One; 2011; 6(11):e27287. PubMed ID: 22073306
[TBL] [Abstract][Full Text] [Related]
12. Secretion of sterols and the NPC2 protein from primary astrocytes.
Mutka AL; Lusa S; Linder MD; Jokitalo E; Kopra O; Jauhiainen M; Ikonen E
J Biol Chem; 2004 Nov; 279(47):48654-62. PubMed ID: 15355983
[TBL] [Abstract][Full Text] [Related]
13. Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.
Storch J; Xu Z
Biochim Biophys Acta; 2009 Jul; 1791(7):671-8. PubMed ID: 19232397
[TBL] [Abstract][Full Text] [Related]
14. Sterol transfer between cyclodextrin and membranes: similar but not identical mechanism to NPC2-mediated cholesterol transfer.
McCauliff LA; Xu Z; Storch J
Biochemistry; 2011 Aug; 50(34):7341-7349. PubMed ID: 21740003
[TBL] [Abstract][Full Text] [Related]
15. Neuronal localization and association of Niemann Pick C2 protein (HE1/NPC2) with the postsynaptic density.
Ong WY; Sundaram RK; Huang E; Ghoshal S; Kumar U; Pentchev PG; Patel SC
Neuroscience; 2004; 128(3):561-70. PubMed ID: 15381285
[TBL] [Abstract][Full Text] [Related]
16. Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport.
Cheruku SR; Xu Z; Dutia R; Lobel P; Storch J
J Biol Chem; 2006 Oct; 281(42):31594-604. PubMed ID: 16606609
[TBL] [Abstract][Full Text] [Related]
17. Structure and function of the NPC2 protein.
Vanier MT; Millat G
Biochim Biophys Acta; 2004 Oct; 1685(1-3):14-21. PubMed ID: 15465422
[TBL] [Abstract][Full Text] [Related]
18. The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.
Ko DC; Binkley J; Sidow A; Scott MP
Proc Natl Acad Sci U S A; 2003 Mar; 100(5):2518-25. PubMed ID: 12591949
[TBL] [Abstract][Full Text] [Related]
19. Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation.
Willenborg M; Schmidt CK; Braun P; Landgrebe J; von Figura K; Saftig P; Eskelinen EL
J Lipid Res; 2005 Dec; 46(12):2559-69. PubMed ID: 16177447
[TBL] [Abstract][Full Text] [Related]
20. Niemann-Pick type C disease: a QM/MM study of conformational changes in cholesterol in the NPC1(NTD) and NPC2 binding pockets.
Elghobashi-Meinhardt N
Biochemistry; 2014 Oct; 53(41):6603-14. PubMed ID: 25251378
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
