152 related articles for article (PubMed ID: 17028580)
1. Probing cell-division phenotype space and Polo-like kinase function using small molecules.
Peters U; Cherian J; Kim JH; Kwok BH; Kapoor TM
Nat Chem Biol; 2006 Nov; 2(11):618-26. PubMed ID: 17028580
[TBL] [Abstract][Full Text] [Related]
2. Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance.
McInnes C; Mazumdar A; Mezna M; Meades C; Midgley C; Scaerou F; Carpenter L; Mackenzie M; Taylor P; Walkinshaw M; Fischer PM; Glover D
Nat Chem Biol; 2006 Nov; 2(11):608-17. PubMed ID: 17028581
[TBL] [Abstract][Full Text] [Related]
3. Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology.
Schöffski P
Oncologist; 2009 Jun; 14(6):559-70. PubMed ID: 19474163
[TBL] [Abstract][Full Text] [Related]
4. Polo-like kinase 1 inhibitors in mono- and combination therapies: a new strategy for treating malignancies.
Christoph DC; Schuler M
Expert Rev Anticancer Ther; 2011 Jul; 11(7):1115-30. PubMed ID: 21806334
[TBL] [Abstract][Full Text] [Related]
5. Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment.
Emanuele MJ; Stukenberg PT
Cell; 2007 Sep; 130(5):893-905. PubMed ID: 17803911
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors.
Zhao C; Tovar C; Yin X; Xu Q; Todorov IT; Vassilev LT; Chen L
Bioorg Med Chem Lett; 2009 Jan; 19(2):319-23. PubMed ID: 19071019
[TBL] [Abstract][Full Text] [Related]
7. Dynamics of the mitotic spindle--potential therapeutic targets.
Miyamoto DT; Perlman ZE; Mitchison TJ; Shirasu-Hiza M
Prog Cell Cycle Res; 2003; 5():349-60. PubMed ID: 14593729
[TBL] [Abstract][Full Text] [Related]
8. Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.
Salmela AL; Pouwels J; Mäki-Jouppila J; Kohonen P; Toivonen P; Kallio L; Kallio M
Carcinogenesis; 2013 Feb; 34(2):436-45. PubMed ID: 23104179
[TBL] [Abstract][Full Text] [Related]
9. Cell division cycle 7 kinase inhibitors: 1H-pyrrolo[2,3-b]pyridines, synthesis and structure-activity relationships.
Ermoli A; Bargiotti A; Brasca MG; Ciavolella A; Colombo N; Fachin G; Isacchi A; Menichincheri M; Molinari A; Montagnoli A; Pillan A; Rainoldi S; Sirtori FR; Sola F; Thieffine S; Tibolla M; Valsasina B; Volpi D; Santocanale C; Vanotti E
J Med Chem; 2009 Jul; 52(14):4380-90. PubMed ID: 19555113
[TBL] [Abstract][Full Text] [Related]
10. Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding.
Srivastava P; Panda D
FEBS J; 2007 Sep; 274(18):4788-801. PubMed ID: 17697112
[TBL] [Abstract][Full Text] [Related]
11. A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
Montagnoli A; Valsasina B; Croci V; Menichincheri M; Rainoldi S; Marchesi V; Tibolla M; Tenca P; Brotherton D; Albanese C; Patton V; Alzani R; Ciavolella A; Sola F; Molinari A; Volpi D; Avanzi N; Fiorentini F; Cattoni M; Healy S; Ballinari D; Pesenti E; Isacchi A; Moll J; Bensimon A; Vanotti E; Santocanale C
Nat Chem Biol; 2008 Jun; 4(6):357-65. PubMed ID: 18469809
[TBL] [Abstract][Full Text] [Related]
12. Small molecules keep mitotic kinases in check.
Strebhardt K
ACS Chem Biol; 2006 Dec; 1(11):683-6. PubMed ID: 17184131
[TBL] [Abstract][Full Text] [Related]
13. Mitotic drivers--inhibitors of the Aurora B Kinase.
Keen N; Taylor S
Cancer Metastasis Rev; 2009 Jun; 28(1-2):185-95. PubMed ID: 19189202
[TBL] [Abstract][Full Text] [Related]
14. Identification of Ustilago maydis Aurora kinase as a novel antifungal target.
Tückmantel S; Greul JN; Janning P; Brockmeyer A; Grütter C; Simard JR; Gutbrod O; Beck ME; Tietjen K; Rauh D; Schreier PH
ACS Chem Biol; 2011 Sep; 6(9):926-33. PubMed ID: 21671622
[TBL] [Abstract][Full Text] [Related]
15. Substituted 2-arylbenzothiazoles as kinase inhibitors: hit-to-lead optimization.
Tasler S; Müller O; Wieber T; Herz T; Pegoraro S; Saeb W; Lang M; Krauss R; Totzke F; Zirrgiebel U; Ehlert JE; Kubbutat MH; Schächtele C
Bioorg Med Chem; 2009 Sep; 17(18):6728-37. PubMed ID: 19692247
[TBL] [Abstract][Full Text] [Related]
16. Novel Mps1 kinase inhibitors: from purine to pyrrolopyrimidine and quinazoline leads.
Bursavich MG; Dastrup D; Shenderovich M; Yager KM; Cimbora DM; Williams B; Kumar DV
Bioorg Med Chem Lett; 2013 Dec; 23(24):6829-33. PubMed ID: 24183538
[TBL] [Abstract][Full Text] [Related]
17. Validation of a flow cytometry based G(2)M delay cell cycle assay for use in evaluating the pharmacodynamic response to Aurora A inhibition.
Estevam J; Danaee H; Liu R; Ecsedy J; Trepicchio WL; Wyant T
J Immunol Methods; 2011 Jan; 363(2):135-42. PubMed ID: 20887727
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and evaluation of alpha-hydroxymethylated conjugated nitroalkenes for their anticancer activity: inhibition of cell proliferation by targeting microtubules.
Mohan R; Rastogi N; Namboothiri IN; Mobin SM; Panda D
Bioorg Med Chem; 2006 Dec; 14(23):8073-85. PubMed ID: 16891118
[TBL] [Abstract][Full Text] [Related]
19. Aminopyrimidinone cdc7 kinase inhibitors.
Woods KW; Lai C; Miyashiro JM; Tong Y; Florjancic AS; Han EK; Soni N; Shi Y; Lasko L; Leverson JD; Johnson EF; Shoemaker AR; Penning TD
Bioorg Med Chem Lett; 2012 Mar; 22(5):1940-3. PubMed ID: 22326396
[TBL] [Abstract][Full Text] [Related]
20. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
Mayer TU; Kapoor TM; Haggarty SJ; King RW; Schreiber SL; Mitchison TJ
Science; 1999 Oct; 286(5441):971-4. PubMed ID: 10542155
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]