280 related articles for article (PubMed ID: 17034150)
41. Synthesis and biological evaluation of 1,4-diaryl-2-azetidinones as specific anticancer agents: activation of adenosine monophosphate activated protein kinase and induction of apoptosis.
Tripodi F; Pagliarin R; Fumagalli G; Bigi A; Fusi P; Orsini F; Frattini M; Coccetti P
J Med Chem; 2012 Mar; 55(5):2112-24. PubMed ID: 22329561
[TBL] [Abstract][Full Text] [Related]
42. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
O'Boyle NM; Carr M; Greene LM; Bergin O; Nathwani SM; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
J Med Chem; 2010 Dec; 53(24):8569-84. PubMed ID: 21080725
[TBL] [Abstract][Full Text] [Related]
43. Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles.
Saczewski F; Reszka P; Gdaniec M; Grünert R; Bednarski PJ
J Med Chem; 2004 Jun; 47(13):3438-49. PubMed ID: 15189040
[TBL] [Abstract][Full Text] [Related]
44. [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
Mahboobi S; Sellmer A; Höcher H; Eichhorn E; Bär T; Schmidt M; Maier T; Stadlwieser JF; Beckers TL
J Med Chem; 2006 Sep; 49(19):5769-76. PubMed ID: 16970401
[TBL] [Abstract][Full Text] [Related]
45. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
Lee HY; Chang JY; Nien CY; Kuo CC; Shih KH; Wu CH; Chang CY; Lai WY; Liou JP
J Med Chem; 2011 Dec; 54(24):8517-25. PubMed ID: 22060033
[TBL] [Abstract][Full Text] [Related]
46. Synthesis and biological evaluation of cinnamido linked benzophenone hybrids as tubulin polymerization inhibitors and apoptosis inducing agents.
Kamal A; Reddy ChR; Vishnuvardhan MV; Mahesh R; Lakshma Nayak V; Prabhakar S; Reddy CS
Bioorg Med Chem Lett; 2014 May; 24(10):2309-14. PubMed ID: 24736114
[TBL] [Abstract][Full Text] [Related]
47. Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors.
Kamal A; Reddy MK; Shaik TB; Rajender ; Srikanth YV; Reddy VS; Kumar GB; Kalivendi SV
Eur J Med Chem; 2012 Apr; 50():9-17. PubMed ID: 22361684
[TBL] [Abstract][Full Text] [Related]
48. Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents.
Hamze A; Giraud A; Messaoudi S; Provot O; Peyrat JF; Bignon J; Liu JM; Wdzieczak-Bakala J; Thoret S; Dubois J; Brion JD; Alami M
ChemMedChem; 2009 Nov; 4(11):1912-24. PubMed ID: 19790205
[TBL] [Abstract][Full Text] [Related]
49. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
[TBL] [Abstract][Full Text] [Related]
50. Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agent.
Shetty RS; Lee Y; Liu B; Husain A; Joseph RW; Lu Y; Nelson D; Mihelcic J; Chao W; Moffett KK; Schumacher A; Flubacher D; Stojanovic A; Bukhtiyarova M; Williams K; Lee KJ; Ochman AR; Saporito MS; Moore WR; Flynn GA; Dorsey BD; Springman EB; Fujimoto T; Kelly MJ
J Med Chem; 2011 Jan; 54(1):179-200. PubMed ID: 21126027
[TBL] [Abstract][Full Text] [Related]
51. Synthesis and Src kinase inhibitory activity of 2-phenyl- and 2-thienyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles.
Boschelli DH; Wu B; Barrios Sosa AC; Durutlic H; Chen JJ; Wang Y; Golas JM; Lucas J; Boschelli F
J Med Chem; 2005 Jun; 48(11):3891-902. PubMed ID: 15916442
[TBL] [Abstract][Full Text] [Related]
52. Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation.
Li YW; Liu J; Liu N; Shi D; Zhou XT; Lv JG; Zhu J; Zheng CH; Zhou YJ
Bioorg Med Chem; 2011 Jun; 19(11):3579-84. PubMed ID: 21536450
[TBL] [Abstract][Full Text] [Related]
53. Novel derivatives of pyridylbenzo[b]thiophene-2-carboxamides and benzo[b]thieno[2,3-c]naphthyridin-2-ones: minor structural variations provoke major differences of antitumor action mechanisms.
Ester K; Hranjec M; Piantanida I; Caleta I; Jarak I; Pavelić K; Kralj M; Karminski-Zamola G
J Med Chem; 2009 Apr; 52(8):2482-92. PubMed ID: 19331416
[TBL] [Abstract][Full Text] [Related]
54. Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: Synthesis and in vitro cytotoxic activity.
Metwally K; Pratsinis H; Kletsas D
Eur J Med Chem; 2007 Mar; 42(3):344-50. PubMed ID: 17141923
[TBL] [Abstract][Full Text] [Related]
55. Novel tubulin-polymerization inhibitor derived from thalidomide directly induces apoptosis in human multiple myeloma cells: possible anti-myeloma mechanism of thalidomide.
Iguchi T; Yachide-Noguchi T; Hashimoto Y; Nakazato S; Sagawa M; Ikeda Y; Kizaki M
Int J Mol Med; 2008 Feb; 21(2):163-8. PubMed ID: 18204782
[TBL] [Abstract][Full Text] [Related]
56. Design, synthesis and preliminary biological evaluation of N-hydroxy-4-(3-phenylpropanamido)benzamide (HPPB) derivatives as novel histone deacetylase inhibitors.
Jiao J; Fang H; Wang X; Guan P; Yuan Y; Xu W
Eur J Med Chem; 2009 Nov; 44(11):4470-6. PubMed ID: 19608304
[TBL] [Abstract][Full Text] [Related]
57. Synthesis and biological evaluation of 1-benzylidene-3,4-dihydronaphthalen-2-one as a new class of microtubule-targeting agents.
Liu J; Zheng CH; Ren XH; Zhou F; Li W; Zhu J; Lv JG; Zhou YJ
J Med Chem; 2012 Jun; 55(12):5720-33. PubMed ID: 22676247
[TBL] [Abstract][Full Text] [Related]
58. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
Ouyang X; Chen X; Piatnitski EL; Kiselyov AS; He HY; Mao Y; Pattaropong V; Yu Y; Kim KH; Kincaid J; Smith L; Wong WC; Lee SP; Milligan DL; Malikzay A; Fleming J; Gerlak J; Deevi D; Doody JF; Chiang HH; Patel SN; Wang Y; Rolser RL; Kussie P; Labelle M; Tuma MC
Bioorg Med Chem Lett; 2005 Dec; 15(23):5154-9. PubMed ID: 16198562
[TBL] [Abstract][Full Text] [Related]
59. Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.
Jiang J; Sun B; Wang YY; Cui M; Zhang L; Cui CZ; Wang YF; Liu XG; Lou HX
Bioorg Med Chem; 2012 Apr; 20(7):2382-91. PubMed ID: 22365913
[TBL] [Abstract][Full Text] [Related]
60. Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers.
Zhang HZ; Crogan-Grundy C; May C; Drewe J; Tseng B; Cai SX
Bioorg Med Chem; 2009 Apr; 17(7):2852-8. PubMed ID: 19282188
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]