276 related articles for article (PubMed ID: 17041103)
21. Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration.
Garcia-Saez I; DeBonis S; Lopez R; Trucco F; Rousseau B; Thuéry P; Kozielski F
J Biol Chem; 2007 Mar; 282(13):9740-9747. PubMed ID: 17251189
[TBL] [Abstract][Full Text] [Related]
22. Weakened spindle checkpoint with reduced BubR1 expression in paclitaxel-resistant ovarian carcinoma cell line SKOV3-TR30.
Fu Y; Ye D; Chen H; Lu W; Ye F; Xie X
Gynecol Oncol; 2007 Apr; 105(1):66-73. PubMed ID: 17234259
[TBL] [Abstract][Full Text] [Related]
23. Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix.
Kapoor TM; Mitchison TJ
J Cell Biol; 2001 Sep; 154(6):1125-33. PubMed ID: 11564753
[TBL] [Abstract][Full Text] [Related]
24. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
Hauf S; Cole RW; LaTerra S; Zimmer C; Schnapp G; Walter R; Heckel A; van Meel J; Rieder CL; Peters JM
J Cell Biol; 2003 Apr; 161(2):281-94. PubMed ID: 12707311
[TBL] [Abstract][Full Text] [Related]
25. Re-evaluating the role of Tao1 in the spindle checkpoint.
Westhorpe FG; Diez MA; Gurden MD; Tighe A; Taylor SS
Chromosoma; 2010 Aug; 119(4):371-9. PubMed ID: 20162290
[TBL] [Abstract][Full Text] [Related]
26. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
Chung KS; Choi HE; Shin JS; Cho YW; Choi JH; Cho WJ; Lee KT
Carcinogenesis; 2013 Aug; 34(8):1852-60. PubMed ID: 23615402
[TBL] [Abstract][Full Text] [Related]
27. Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay.
Tanudji M; Shoemaker J; L'Italien L; Russell L; Chin G; Schebye XM
Mol Biol Cell; 2004 Aug; 15(8):3771-81. PubMed ID: 15181147
[TBL] [Abstract][Full Text] [Related]
28. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.
Vogel C; Hager C; Bastians H
Cancer Res; 2007 Jan; 67(1):339-45. PubMed ID: 17210716
[TBL] [Abstract][Full Text] [Related]
29. S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.
Skoufias DA; DeBonis S; Saoudi Y; Lebeau L; Crevel I; Cross R; Wade RH; Hackney D; Kozielski F
J Biol Chem; 2006 Jun; 281(26):17559-69. PubMed ID: 16507573
[TBL] [Abstract][Full Text] [Related]
30. Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells.
Kollu S; Bakhoum SF; Compton DA
Curr Biol; 2009 Dec; 19(24):2108-13. PubMed ID: 19931454
[TBL] [Abstract][Full Text] [Related]
31. Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5.
Kozielski F; Skoufias DA; Indorato RL; Saoudi Y; Jungblut PR; Hustoft HK; Strozynski M; Thiede B
Proteomics; 2008 Jan; 8(2):289-300. PubMed ID: 18186019
[TBL] [Abstract][Full Text] [Related]
32. Caspase-mediated specific cleavage of BubR1 is a determinant of mitotic progression.
Kim M; Murphy K; Liu F; Parker SE; Dowling ML; Baff W; Kao GD
Mol Cell Biol; 2005 Nov; 25(21):9232-48. PubMed ID: 16227576
[TBL] [Abstract][Full Text] [Related]
33. Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells.
Al-Obaidi N; Mitchison TJ; Crews CM; Mayer TU
ACS Chem Biol; 2016 Jun; 11(6):1544-51. PubMed ID: 27121275
[TBL] [Abstract][Full Text] [Related]
34. Mutations in the human kinesin Eg5 that confer resistance to monastrol and S-trityl-L-cysteine in tumor derived cell lines.
Tcherniuk S; van Lis R; Kozielski F; Skoufias DA
Biochem Pharmacol; 2010 Mar; 79(6):864-72. PubMed ID: 19896928
[TBL] [Abstract][Full Text] [Related]
35. p55CDC/hCDC20 mutant induces mitotic catastrophe by inhibiting the MAD2-dependent spindle checkpoint activity in tumor cells.
Sihn CR; Suh EJ; Lee KH; Kim TY; Kim SH
Cancer Lett; 2003 Nov; 201(2):203-10. PubMed ID: 14607335
[TBL] [Abstract][Full Text] [Related]
36. Transient exposure to the Eg5 kinesin inhibitor monastrol leads to syntelic orientation of chromosomes and aneuploidy in mouse oocytes.
Mailhes JB; Mastromatteo C; Fuseler JW
Mutat Res; 2004 Apr; 559(1-2):153-67. PubMed ID: 15066583
[TBL] [Abstract][Full Text] [Related]
37. Roles of polo-like kinase 1 in the assembly of functional mitotic spindles.
Sumara I; Giménez-Abián JF; Gerlich D; Hirota T; Kraft C; de la Torre C; Ellenberg J; Peters JM
Curr Biol; 2004 Oct; 14(19):1712-22. PubMed ID: 15458642
[TBL] [Abstract][Full Text] [Related]
38. Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells.
Bargiela-Iparraguirre J; Prado-Marchal L; Pajuelo-Lozano N; Jiménez B; Perona R; Sánchez-Pérez I
Cell Cycle; 2014; 13(22):3590-601. PubMed ID: 25483095
[TBL] [Abstract][Full Text] [Related]
39. Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
Yamada HY; Gorbsky GJ
Mol Cancer Ther; 2006 Jan; 5(1):29-38. PubMed ID: 16432160
[TBL] [Abstract][Full Text] [Related]
40. Monastrol, a prototype anti-cancer drug that inhibits a mitotic kinesin, induces rapid bursts of axonal outgrowth from cultured postmitotic neurons.
Haque SA; Hasaka TP; Brooks AD; Lobanov PV; Baas PW
Cell Motil Cytoskeleton; 2004 May; 58(1):10-6. PubMed ID: 14983520
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
