248 related articles for article (PubMed ID: 17043353)
1. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
Lee JN; Song B; DeBose-Boyd RA; Ye J
J Biol Chem; 2006 Dec; 281(51):39308-15. PubMed ID: 17043353
[TBL] [Abstract][Full Text] [Related]
2. Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.
Jo Y; Lee PC; Sguigna PV; DeBose-Boyd RA
Proc Natl Acad Sci U S A; 2011 Dec; 108(51):20503-8. PubMed ID: 22143767
[TBL] [Abstract][Full Text] [Related]
3. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
Song BL; Sever N; DeBose-Boyd RA
Mol Cell; 2005 Sep; 19(6):829-40. PubMed ID: 16168377
[TBL] [Abstract][Full Text] [Related]
4. Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.
Sever N; Song BL; Yabe D; Goldstein JL; Brown MS; DeBose-Boyd RA
J Biol Chem; 2003 Dec; 278(52):52479-90. PubMed ID: 14563840
[TBL] [Abstract][Full Text] [Related]
5. Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Sever N; Lee PC; Song BL; Rawson RB; Debose-Boyd RA
J Biol Chem; 2004 Oct; 279(41):43136-47. PubMed ID: 15247248
[TBL] [Abstract][Full Text] [Related]
6. Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2.
Lee PC; Sever N; Debose-Boyd RA
J Biol Chem; 2005 Jul; 280(26):25242-9. PubMed ID: 15866869
[TBL] [Abstract][Full Text] [Related]
7. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.
Jiang LY; Jiang W; Tian N; Xiong YN; Liu J; Wei J; Wu KY; Luo J; Shi XJ; Song BL
J Biol Chem; 2018 Mar; 293(11):4047-4055. PubMed ID: 29374057
[TBL] [Abstract][Full Text] [Related]
8. Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.
Nguyen AD; Lee SH; DeBose-Boyd RA
J Biol Chem; 2009 Sep; 284(39):26778-88. PubMed ID: 19638338
[TBL] [Abstract][Full Text] [Related]
9. Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.
Song BL; DeBose-Boyd RA
J Biol Chem; 2004 Jul; 279(27):28798-806. PubMed ID: 15090540
[TBL] [Abstract][Full Text] [Related]
10. Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
Tsai YC; Leichner GS; Pearce MM; Wilson GL; Wojcikiewicz RJ; Roitelman J; Weissman AM
Mol Biol Cell; 2012 Dec; 23(23):4484-94. PubMed ID: 23087214
[TBL] [Abstract][Full Text] [Related]
11. Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Jo Y; Sguigna PV; DeBose-Boyd RA
J Biol Chem; 2011 Apr; 286(17):15022-31. PubMed ID: 21343306
[TBL] [Abstract][Full Text] [Related]
12. Membrane topology of human insig-1, a protein regulator of lipid synthesis.
Feramisco JD; Goldstein JL; Brown MS
J Biol Chem; 2004 Feb; 279(9):8487-96. PubMed ID: 14660594
[TBL] [Abstract][Full Text] [Related]
13. Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase.
Jo Y; Debose-Boyd RA
Crit Rev Biochem Mol Biol; 2010 Jun; 45(3):185-98. PubMed ID: 20482385
[TBL] [Abstract][Full Text] [Related]
14. Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
Gong Y; Lee JN; Lee PC; Goldstein JL; Brown MS; Ye J
Cell Metab; 2006 Jan; 3(1):15-24. PubMed ID: 16399501
[TBL] [Abstract][Full Text] [Related]
15. Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes.
Ikeda Y; Demartino GN; Brown MS; Lee JN; Goldstein JL; Ye J
J Biol Chem; 2009 Dec; 284(50):34889-900. PubMed ID: 19815544
[TBL] [Abstract][Full Text] [Related]
16. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells.
Faulkner RA; Nguyen AD; Jo Y; DeBose-Boyd RA
J Lipid Res; 2013 Apr; 54(4):1011-22. PubMed ID: 23403031
[TBL] [Abstract][Full Text] [Related]
17. Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain.
Sever N; Yang T; Brown MS; Goldstein JL; DeBose-Boyd RA
Mol Cell; 2003 Jan; 11(1):25-33. PubMed ID: 12535518
[TBL] [Abstract][Full Text] [Related]
18. Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells.
Elsabrouty R; Jo Y; Dinh TT; DeBose-Boyd RA
Mol Biol Cell; 2013 Nov; 24(21):3300-8. PubMed ID: 24025715
[TBL] [Abstract][Full Text] [Related]
19. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
Yang T; Espenshade PJ; Wright ME; Yabe D; Gong Y; Aebersold R; Goldstein JL; Brown MS
Cell; 2002 Aug; 110(4):489-500. PubMed ID: 12202038
[TBL] [Abstract][Full Text] [Related]
20. Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes.
Jo Y; Hartman IZ; DeBose-Boyd RA
Mol Biol Cell; 2013 Feb; 24(3):169-83. PubMed ID: 23223569
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
