259 related articles for article (PubMed ID: 17045926)
1. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models.
Kanthasamy AG; Anantharam V; Zhang D; Latchoumycandane C; Jin H; Kaul S; Kanthasamy A
Free Radic Biol Med; 2006 Nov; 41(10):1578-89. PubMed ID: 17045926
[TBL] [Abstract][Full Text] [Related]
2. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
Anantharam V; Kitazawa M; Latchoumycandane C; Kanthasamy A; Kanthasamy AG
Ann N Y Acad Sci; 2004 Dec; 1035():271-89. PubMed ID: 15681813
[TBL] [Abstract][Full Text] [Related]
3. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.
Kitazawa M; Anantharam V; Kanthasamy AG
Neuroscience; 2003; 119(4):945-64. PubMed ID: 12831855
[TBL] [Abstract][Full Text] [Related]
4. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.
Yang Y; Kaul S; Zhang D; Anantharam V; Kanthasamy AG
Mol Cell Neurosci; 2004 Mar; 25(3):406-21. PubMed ID: 15033169
[TBL] [Abstract][Full Text] [Related]
5. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
Kaul S; Kanthasamy A; Kitazawa M; Anantharam V; Kanthasamy AG
Eur J Neurosci; 2003 Sep; 18(6):1387-401. PubMed ID: 14511319
[TBL] [Abstract][Full Text] [Related]
6. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.
Latchoumycandane C; Anantharam V; Jin H; Kanthasamy A; Kanthasamy A
Toxicol Appl Pharmacol; 2011 Nov; 256(3):314-23. PubMed ID: 21846476
[TBL] [Abstract][Full Text] [Related]
7. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.
Latchoumycandane C; Anantharam V; Kitazawa M; Yang Y; Kanthasamy A; Kanthasamy AG
J Pharmacol Exp Ther; 2005 Apr; 313(1):46-55. PubMed ID: 15608081
[TBL] [Abstract][Full Text] [Related]
8. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
Afeseh Ngwa H; Kanthasamy A; Anantharam V; Song C; Witte T; Houk R; Kanthasamy AG
Toxicol Appl Pharmacol; 2009 Oct; 240(2):273-85. PubMed ID: 19646462
[TBL] [Abstract][Full Text] [Related]
9. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
Kaul S; Anantharam V; Yang Y; Choi CJ; Kanthasamy A; Kanthasamy AG
J Biol Chem; 2005 Aug; 280(31):28721-30. PubMed ID: 15961393
[TBL] [Abstract][Full Text] [Related]
10. Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons.
Bilsland J; Roy S; Xanthoudakis S; Nicholson DW; Han Y; Grimm E; Hefti F; Harper SJ
J Neurosci; 2002 Apr; 22(7):2637-49. PubMed ID: 11923429
[TBL] [Abstract][Full Text] [Related]
11. Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.
Zhang D; Anantharam V; Kanthasamy A; Kanthasamy AG
J Pharmacol Exp Ther; 2007 Sep; 322(3):913-22. PubMed ID: 17565007
[TBL] [Abstract][Full Text] [Related]
12. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.
Kanthasamy AG; Kitazawa M; Yang Y; Anantharam V; Kanthasamy A
Mol Brain; 2008 Oct; 1():12. PubMed ID: 18945348
[TBL] [Abstract][Full Text] [Related]
13. Caspase-mediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cells.
Kato K; Yamanouchi D; Esbona K; Kamiya K; Zhang F; Kent KC; Liu B
Am J Physiol Heart Circ Physiol; 2009 Dec; 297(6):H2253-61. PubMed ID: 19837952
[TBL] [Abstract][Full Text] [Related]
14. Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.
Kaul S; Anantharam V; Kanthasamy A; Kanthasamy AG
Brain Res Mol Brain Res; 2005 Sep; 139(1):137-52. PubMed ID: 15978696
[TBL] [Abstract][Full Text] [Related]
15. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
Anantharam V; Kitazawa M; Wagner J; Kaul S; Kanthasamy AG
J Neurosci; 2002 Mar; 22(5):1738-51. PubMed ID: 11880503
[TBL] [Abstract][Full Text] [Related]
16. Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration.
Carvour M; Song C; Kaul S; Anantharam V; Kanthasamy A; Kanthasamy A
Ann N Y Acad Sci; 2008 Oct; 1139():197-205. PubMed ID: 18991865
[TBL] [Abstract][Full Text] [Related]
17. Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals.
von Coelln R; Kügler S; Bähr M; Weller M; Dichgans J; Schulz JB
J Neurochem; 2001 Apr; 77(1):263-73. PubMed ID: 11279282
[TBL] [Abstract][Full Text] [Related]
18. Caspase-dependent and -independent cell death pathways in primary cultures of mesencephalic dopaminergic neurons after neurotoxin treatment.
Han BS; Hong HS; Choi WS; Markelonis GJ; Oh TH; Oh YJ
J Neurosci; 2003 Jun; 23(12):5069-78. PubMed ID: 12832530
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells.
Anantharam V; Kaul S; Song C; Kanthasamy A; Kanthasamy AG
Neurotoxicology; 2007 Sep; 28(5):988-97. PubMed ID: 17904225
[TBL] [Abstract][Full Text] [Related]
20. Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: role of caspases, ROS, and JNK.
Choi WS; Yoon SY; Oh TH; Choi EJ; O'Malley KL; Oh YJ
J Neurosci Res; 1999 Jul; 57(1):86-94. PubMed ID: 10397638
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
