322 related articles for article (PubMed ID: 17046835)
1. PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex.
Lo SC; Hannink M
J Biol Chem; 2006 Dec; 281(49):37893-903. PubMed ID: 17046835
[TBL] [Abstract][Full Text] [Related]
2. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
3. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
Furukawa M; Xiong Y
Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
[TBL] [Abstract][Full Text] [Related]
4. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.
Zhang DD; Lo SC; Sun Z; Habib GM; Lieberman MW; Hannink M
J Biol Chem; 2005 Aug; 280(34):30091-9. PubMed ID: 15983046
[TBL] [Abstract][Full Text] [Related]
5. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
[TBL] [Abstract][Full Text] [Related]
6. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
Lo SC; Hannink M
Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
[TBL] [Abstract][Full Text] [Related]
7. PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria.
Lo SC; Hannink M
Exp Cell Res; 2008 May; 314(8):1789-803. PubMed ID: 18387606
[TBL] [Abstract][Full Text] [Related]
8. Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis.
Niture SK; Jaiswal AK
J Biol Chem; 2011 Dec; 286(52):44542-56. PubMed ID: 22072718
[TBL] [Abstract][Full Text] [Related]
9. Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Lo SC; Li X; Henzl MT; Beamer LJ; Hannink M
EMBO J; 2006 Aug; 25(15):3605-17. PubMed ID: 16888629
[TBL] [Abstract][Full Text] [Related]
10. Mitochondrial phosphatase PGAM5 regulates Keap1-mediated Bcl-xL degradation and controls cardiomyocyte apoptosis driven by myocardial ischemia/reperfusion injury.
Yang C; Liu X; Yang F; Zhang W; Chen Z; Yan D; You Q; Wu X
In Vitro Cell Dev Biol Anim; 2017 Mar; 53(3):248-257. PubMed ID: 27815660
[TBL] [Abstract][Full Text] [Related]
11. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress.
Zhang DD; Hannink M
Mol Cell Biol; 2003 Nov; 23(22):8137-51. PubMed ID: 14585973
[TBL] [Abstract][Full Text] [Related]
12. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
Sun Z; Zhang S; Chan JY; Zhang DD
Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
[TBL] [Abstract][Full Text] [Related]
13. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
Uruno A; Motohashi H
Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
[TBL] [Abstract][Full Text] [Related]
14. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
Stępkowski TM; Kruszewski MK
Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
[TBL] [Abstract][Full Text] [Related]
15. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.
Cullinan SB; Gordan JD; Jin J; Harper JW; Diehl JA
Mol Cell Biol; 2004 Oct; 24(19):8477-86. PubMed ID: 15367669
[TBL] [Abstract][Full Text] [Related]
16. Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
McMahon M; Swift SR; Hayes JD
Toxicol Appl Pharmacol; 2018 Dec; 360():45-57. PubMed ID: 30261176
[TBL] [Abstract][Full Text] [Related]
17. Sp1 is a substrate of Keap1 and regulates the activity of CRL4A
Siswanto FM; Oguro A; Imaoka S
J Biol Chem; 2021; 296():100704. PubMed ID: 33895141
[TBL] [Abstract][Full Text] [Related]
18. Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.
Mulvaney KM; Matson JP; Siesser PF; Tamir TY; Goldfarb D; Jacobs TM; Cloer EW; Harrison JS; Vaziri C; Cook JG; Major MB
J Biol Chem; 2016 Nov; 291(45):23719-23733. PubMed ID: 27621311
[TBL] [Abstract][Full Text] [Related]
19. KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells.
Xu Y; Fang F; Miriyala S; Crooks PA; Oberley TD; Chaiswing L; Noel T; Holley AK; Zhao Y; Kiningham KK; Clair DK; Clair WH
Cancer Res; 2013 Jul; 73(14):4406-17. PubMed ID: 23674500
[TBL] [Abstract][Full Text] [Related]
20. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
Taguchi K; Motohashi H; Yamamoto M
Genes Cells; 2011 Feb; 16(2):123-40. PubMed ID: 21251164
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
