BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 17049047)

  • 1. Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts.
    Van der Luit AH; Budde M; Zerp S; Caan W; Klarenbeek JB; Verheij M; Van Blitterswijk WJ
    Biochem J; 2007 Jan; 401(2):541-9. PubMed ID: 17049047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.
    van Blitterswijk WJ; Klarenbeek JB; van der Luit AH; Alderliesten MC; van Lummel M; Verheij M
    Biochem J; 2009 Dec; 425(1):225-34. PubMed ID: 19824885
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.
    Li Z; Hailemariam TK; Zhou H; Li Y; Duckworth DC; Peake DA; Zhang Y; Kuo MS; Cao G; Jiang XC
    Biochim Biophys Acta; 2007 Sep; 1771(9):1186-94. PubMed ID: 17616479
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis.
    van der Luit AH; Budde M; Ruurs P; Verheij M; van Blitterswijk WJ
    J Biol Chem; 2002 Oct; 277(42):39541-7. PubMed ID: 12183451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells.
    van der Luit AH; Vink SR; Klarenbeek JB; Perrissoud D; Solary E; Verheij M; van Blitterswijk WJ
    Mol Cancer Ther; 2007 Aug; 6(8):2337-45. PubMed ID: 17699729
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different modes of internalization of apoptotic alkyl-lysophospholipid and cell-rescuing lysophosphatidylcholine.
    Van Der Luit AH; Budde M; Verheij M; Van Blitterswijk WJ
    Biochem J; 2003 Sep; 374(Pt 3):747-53. PubMed ID: 12837133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.
    Alderliesten MC; Klarenbeek JB; van der Luit AH; van Lummel M; Jones DR; Zerp S; Divecha N; Verheij M; van Blitterswijk WJ
    Biochem J; 2011 Nov; 440(1):127-35. PubMed ID: 21793801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lipid rafts and metabolic energy differentially determine uptake of anti-cancer alkylphospholipids in lymphoma versus carcinoma cells.
    Vink SR; van der Luit AH; Klarenbeek JB; Verheij M; van Blitterswijk WJ
    Biochem Pharmacol; 2007 Nov; 74(10):1456-65. PubMed ID: 17803969
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells.
    Jin ZX; Huang CR; Dong L; Goda S; Kawanami T; Sawaki T; Sakai T; Tong XP; Masaki Y; Fukushima T; Tanaka M; Mimori T; Tojo H; Bloom ET; Okazaki T; Umehara H
    Int Immunol; 2008 Nov; 20(11):1427-37. PubMed ID: 18820264
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria.
    Mollinedo F; Fernández M; Hornillos V; Delgado J; Amat-Guerri F; Acuña AU; Nieto-Miguel T; Villa-Pulgarín JA; González-García C; Ceña V; Gajate C
    Cell Death Dis; 2011 May; 2(5):e158. PubMed ID: 21593790
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sphingomyelin synthase activity affects TRIF-dependent signaling of Toll-like receptor 4 in cells stimulated with lipopolysaccharide.
    Prymas K; Świątkowska A; Traczyk G; Ziemlińska E; Dziewulska A; Ciesielska A; Kwiatkowska K
    Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Feb; 1865(2):158549. PubMed ID: 31678513
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.
    Mollinedo F; de la Iglesia-Vicente J; Gajate C; Estella-Hermoso de Mendoza A; Villa-Pulgarin JA; de Frias M; Roué G; Gil J; Colomer D; Campanero MA; Blanco-Prieto MJ
    Clin Cancer Res; 2010 Apr; 16(7):2046-54. PubMed ID: 20233887
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.
    Barceló-Coblijn G; Martin ML; de Almeida RF; Noguera-Salvà MA; Marcilla-Etxenike A; Guardiola-Serrano F; Lüth A; Kleuser B; Halver JE; Escribá PV
    Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19569-74. PubMed ID: 22106271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of membrane sphingomyelin and ceramide in platform formation for Fas-mediated apoptosis.
    Miyaji M; Jin ZX; Yamaoka S; Amakawa R; Fukuhara S; Sato SB; Kobayashi T; Domae N; Mimori T; Bloom ET; Okazaki T; Umehara H
    J Exp Med; 2005 Jul; 202(2):249-59. PubMed ID: 16009715
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury.
    Anjum F; Joshi K; Grinkina N; Gowda S; Cutaia M; Wadgaonkar R
    Am J Respir Cell Mol Biol; 2012 Jul; 47(1):94-103. PubMed ID: 22362386
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells.
    Yachi R; Uchida Y; Balakrishna BH; Anderluh G; Kobayashi T; Taguchi T; Arai H
    Genes Cells; 2012 Aug; 17(8):720-7. PubMed ID: 22747662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast.
    Cuesta-Marbán Á; Botet J; Czyz O; Cacharro LM; Gajate C; Hornillos V; Delgado J; Zhang H; Amat-Guerri F; Acuña AU; McMaster CR; Revuelta JL; Zaremberg V; Mollinedo F
    J Biol Chem; 2013 Mar; 288(12):8405-8418. PubMed ID: 23335509
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methods to Characterize Synthesis and Degradation of Sphingomyelin at the Plasma Membrane and Its Impact on Lipid Raft Dynamics.
    Nikolova-Karakashian M
    Methods Mol Biol; 2021; 2187():113-129. PubMed ID: 32770504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis.
    Lee EJ; Yun UJ; Koo KH; Sung JY; Shim J; Ye SK; Hong KM; Kim YN
    Biochim Biophys Acta; 2014 Jan; 1841(1):190-203. PubMed ID: 24120917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.
    Ding T; Li Z; Hailemariam T; Mukherjee S; Maxfield FR; Wu MP; Jiang XC
    J Lipid Res; 2008 Feb; 49(2):376-85. PubMed ID: 17982138
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.