BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

74 related articles for article (PubMed ID: 17049467)

  • 1. Activation of Rac1 by Rho-guanine nucleotide dissociation inhibitor-beta with defective isoprenyl-binding pocket.
    Ota T; Maeda M; Murakami M; Takegami T; Suto S; Tatsuka M
    Cell Biol Int; 2007 Jan; 31(1):92-6. PubMed ID: 17049467
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI.
    Golovanov AP; Chuang TH; DerMardirossian C; Barsukov I; Hawkins D; Badii R; Bokoch GM; Lian LY; Roberts GC
    J Mol Biol; 2001 Jan; 305(1):121-35. PubMed ID: 11114252
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LyGDI functions in cancer metastasis by anchoring Rho proteins to the cell membrane.
    Ota T; Maeda M; Suto S; Tatsuka M
    Mol Carcinog; 2004 Apr; 39(4):206-20. PubMed ID: 15057873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1.
    Otsuki Y; Tanaka M; Yoshii S; Kawazoe N; Nakaya K; Sugimura H
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4385-90. PubMed ID: 11274357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors.
    Karnoub AE; Worthylake DK; Rossman KL; Pruitt WM; Campbell SL; Sondek J; Der CJ
    Nat Struct Biol; 2001 Dec; 8(12):1037-41. PubMed ID: 11685227
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RhoGDIbeta lacking the N-terminal regulatory domain suppresses metastasis by promoting anoikis in v-src-transformed cells.
    Ota T; Maeda M; Sakita-Suto S; Zhou X; Murakami M; Takegami T; Tatsuka M
    Clin Exp Metastasis; 2006; 23(7-8):323-34. PubMed ID: 17111235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1.
    Lian LY; Barsukov I; Golovanov AP; Hawkins DI; Badii R; Sze KH; Keep NH; Bokoch GM; Roberts GC
    Structure; 2000 Jan; 8(1):47-55. PubMed ID: 10673424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ZAK negatively regulates RhoGDIbeta-induced Rac1-mediated hypertrophic growth and cell migration.
    Huang CY; Yang LC; Liu KY; Chang IC; Liao PH; Chou JI; Chou MY; Lin WW; Yang JJ
    J Biomed Sci; 2009 Jun; 16(1):56. PubMed ID: 19538723
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Negative charges in the flexible N-terminal domain of Rho GDP-dissociation inhibitors (RhoGDIs) regulate the targeting of the RhoGDI-Rac1 complex to membranes.
    Ueyama T; Son J; Kobayashi T; Hamada T; Nakamura T; Sakaguchi H; Shirafuji T; Saito N
    J Immunol; 2013 Sep; 191(5):2560-9. PubMed ID: 23918979
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
    Worthylake DK; Rossman KL; Sondek J
    Nature; 2000 Dec; 408(6813):682-8. PubMed ID: 11130063
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
    Gosser YQ; Nomanbhoy TK; Aghazadeh B; Manor D; Combs C; Cerione RA; Rosen MK
    Nature; 1997 Jun; 387(6635):814-9. PubMed ID: 9194563
    [TBL] [Abstract][Full Text] [Related]  

  • 12. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
    Niu J; Profirovic J; Pan H; Vaiskunaite R; Voyno-Yasenetskaya T
    Circ Res; 2003 Oct; 93(9):848-56. PubMed ID: 14512443
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells.
    Gandhi PN; Gibson RM; Tong X; Miyoshi J; Takai Y; Konieczkowski M; Sedor JR; Wilson-Delfosse AL
    Biochem J; 2004 Mar; 378(Pt 2):409-19. PubMed ID: 14629200
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How Vav proteins discriminate the GTPases Rac1 and RhoA from Cdc42.
    Movilla N; Dosil M; Zheng Y; Bustelo XR
    Oncogene; 2001 Dec; 20(56):8057-65. PubMed ID: 11781818
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1.
    Illenberger D; Schwald F; Pimmer D; Binder W; Maier G; Dietrich A; Gierschik P
    EMBO J; 1998 Nov; 17(21):6241-9. PubMed ID: 9799233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
    Snyder JT; Worthylake DK; Rossman KL; Betts L; Pruitt WM; Siderovski DP; Der CJ; Sondek J
    Nat Struct Biol; 2002 Jun; 9(6):468-75. PubMed ID: 12006984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading.
    Degani S; Balzac F; Brancaccio M; Guazzone S; Retta SF; Silengo L; Eva A; Tarone G
    J Cell Biol; 2002 Jan; 156(2):377-87. PubMed ID: 11807099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI.
    Scheffzek K; Stephan I; Jensen ON; Illenberger D; Gierschik P
    Nat Struct Biol; 2000 Feb; 7(2):122-6. PubMed ID: 10655614
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Yersinia virulence depends on mimicry of host Rho-family nucleotide dissociation inhibitors.
    Prehna G; Ivanov MI; Bliska JB; Stebbins CE
    Cell; 2006 Sep; 126(5):869-80. PubMed ID: 16959567
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy.
    Custodis F; Eberl M; Kilter H; Böhm M; Laufs U
    Cardiovasc Res; 2006 Jul; 71(2):342-51. PubMed ID: 16698001
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.