These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 17049851)

  • 1. Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions.
    Xu X; Fu R; Chen J; Chen S; Bai X
    Bioorg Med Chem Lett; 2007 Jan; 17(1):101-4. PubMed ID: 17049851
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Azetidinone derivatives: design, synthesis and evaluation of cholesterol absorption inhibitors.
    Wang Y; Zhang H; Huang W; Kong J; Zhou J; Zhang B
    Eur J Med Chem; 2009 Apr; 44(4):1638-43. PubMed ID: 18990470
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption.
    Kvaernø L; Werder M; Hauser H; Carreira EM
    J Med Chem; 2005 Sep; 48(19):6035-53. PubMed ID: 16162006
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A formal synthesis of ezetimibe via cycloaddition/rearrangement cascade reaction.
    Michalak M; Stodulski M; Stecko S; Mames A; Panfil I; Soluch M; Furman B; Chmielewski M
    J Org Chem; 2011 Aug; 76(16):6931-6. PubMed ID: 21744801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of fluorescent biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
    Burnett DA; Caplen MA; Browne ME; Zhau H; Altmann SW; Davis HR; Clader JW
    Bioorg Med Chem Lett; 2002 Feb; 12(3):315-8. PubMed ID: 11814786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.
    Rosenblum SB; Huynh T; Afonso A; Davis HR; Yumibe N; Clader JW; Burnett DA
    J Med Chem; 1998 Mar; 41(6):973-80. PubMed ID: 9526571
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of iodinated biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
    Burnett DA; Caplen MA; Domalski MS; Browne ME; Davis HR; Clader JW
    Bioorg Med Chem Lett; 2002 Feb; 12(3):311-4. PubMed ID: 11814785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ezetimibe and cholesterol absorption.
    Lavoie MA
    Can J Clin Pharmacol; 2003; 10 Suppl A():7A-12A. PubMed ID: 14571301
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Total synthesis of ezetimibe, a cholesterol absorption inhibitor.
    Śnieżek M; Stecko S; Panfil I; Furman B; Chmielewski M
    J Org Chem; 2013 Jul; 78(14):7048-57. PubMed ID: 23763523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats.
    van Heek M; Farley C; Compton DS; Hoos LM; Smith-Torhan A; Davis HR
    Br J Pharmacol; 2003 Apr; 138(8):1459-64. PubMed ID: 12721101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice.
    Zheng S; Hoos L; Cook J; Tetzloff G; Davis H; van Heek M; Hwa JJ
    Eur J Pharmacol; 2008 Apr; 584(1):118-24. PubMed ID: 18329014
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus.
    Clader JW; Burnett DA; Caplen MA; Domalski MS; Dugar S; Vaccaro W; Sher R; Browne ME; Zhao H; Burrier RE; Salisbury B; Davis HR
    J Med Chem; 1996 Sep; 39(19):3684-93. PubMed ID: 8809157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery, synthesis and evaluation of novel cholesterol absorption inhibitors.
    Zhu X; Ji J; Huang D; Zhu Y; Tang C; Yang X; Qian H; Huang W
    Chem Biol Drug Des; 2012 Sep; 80(3):426-33. PubMed ID: 22642541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors.
    Frick W; Bauer-Schäfer A; Bauer J; Girbig F; Corsiero D; Heuer H; Kramer W
    Bioorg Med Chem; 2003 Apr; 11(8):1639-42. PubMed ID: 12659749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity.
    McKittrick BA; Ma K; Huie K; Yumibe N; Davis H; Clader JW; Czarniecki M; McPhail AT
    J Med Chem; 1998 Feb; 41(5):752-9. PubMed ID: 9513603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.
    Hawes BE; O'neill KA; Yao X; Crona JH; Davis HR; Graziano MP; Altmann SW
    Mol Pharmacol; 2007 Jan; 71(1):19-29. PubMed ID: 17005902
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Self-nanoemulsifying granules of ezetimibe: design, optimization and evaluation.
    Dixit RP; Nagarsenker MS
    Eur J Pharm Sci; 2008 Oct; 35(3):183-92. PubMed ID: 18652892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterocyclic ring scaffolds as small-molecule cholesterol absorption inhibitors.
    Ritter T; Kvaernø L; Werder M; Hauser H; Carreira EM
    Org Biomol Chem; 2005 Oct; 3(19):3514-23. PubMed ID: 16172689
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ezetimibe: cholesterol lowering and beyond.
    Bays HE; Neff D; Tomassini JE; Tershakovec AM
    Expert Rev Cardiovasc Ther; 2008 Apr; 6(4):447-70. PubMed ID: 18402536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and stereoelectronic requirements for the inhibition of mammalian 2,3-oxidosqualene cyclase by substituted isoquinoline derivatives.
    Barth MM; Binet JL; Thomas DM; de Fornel DC; Samreth S; Schuber FJ; Renaut PP
    J Med Chem; 1996 Jun; 39(12):2302-12. PubMed ID: 8691425
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.