These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 17050648)

  • 1. CYP2B6, CYP2D6, and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomes.
    Davies BJ; Coller JK; Somogyi AA; Milne RW; Sallustio BC
    Drug Metab Dispos; 2007 Jan; 35(1):128-38. PubMed ID: 17050648
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determination of the 4-monohydroxy metabolites of perhexiline in human plasma, urine and liver microsomes by liquid chromatography.
    Davies BJ; Herbert MK; Coller JK; Somogyi AA; Milne RW; Sallustio BC
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Nov; 843(2):302-9. PubMed ID: 16837252
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of benidipine and its enantiomers' metabolism by human liver cytochrome P450 enzymes.
    Yoon YJ; Kim KB; Kim H; Seo KA; Kim HS; Cha IJ; Kim EY; Liu KH; Shin JG
    Drug Metab Dispos; 2007 Sep; 35(9):1518-24. PubMed ID: 17537876
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of cisapride with the human cytochrome P450 system: metabolism and inhibition studies.
    Desta Z; Soukhova N; Mahal SK; Flockhart DA
    Drug Metab Dispos; 2000 Jul; 28(7):789-800. PubMed ID: 10859153
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A.
    Desta Z; Soukhova N; Morocho AM; Flockhart DA
    J Pharmacol Exp Ther; 2001 Aug; 298(2):508-20. PubMed ID: 11454912
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of human cytochrome P-450 isoforms involved in metabolism of R(+)- and S(-)-gallopamil: utility of in vitro disappearance rate.
    Suzuki A; Iida I; Tanaka F; Akimoto M; Fukushima K; Tani M; Ishizaki T; Chiba K
    Drug Metab Dispos; 1999 Nov; 27(11):1254-9. PubMed ID: 10534309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes.
    Wienkers LC; Allievi C; Hauer MJ; Wynalda MA
    Drug Metab Dispos; 1999 Nov; 27(11):1334-40. PubMed ID: 10534319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
    Kitamura A; Mizuno Y; Natsui K; Yabuki M; Komuro S; Kanamaru H
    Biopharm Drug Dispos; 2005 Mar; 26(2):59-65. PubMed ID: 15619261
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline.
    Davies BJ; Herbert MK; Coller JK; Somogyi AA; Milne RW; Sallustio BC
    Br J Clin Pharmacol; 2008 Mar; 65(3):347-54. PubMed ID: 17875193
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereoselective metabolism of lansoprazole by human liver cytochrome P450 enzymes.
    Kim KA; Kim MJ; Park JY; Shon JH; Yoon YR; Lee SS; Liu KH; Chun JH; Hyun MH; Shin JG
    Drug Metab Dispos; 2003 Oct; 31(10):1227-34. PubMed ID: 12975331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes.
    Zhu M; Zhao W; Jimenez H; Zhang D; Yeola S; Dai R; Vachharajani N; Mitroka J
    Drug Metab Dispos; 2005 Apr; 33(4):500-7. PubMed ID: 15640381
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia.
    Inglis SC; Herbert MK; Davies BJ; Coller JK; James HM; Horowitz JD; Morris RG; Milne RW; Somogyi AA; Sallustio BC
    Pharmacogenet Genomics; 2007 May; 17(5):305-12. PubMed ID: 17429312
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
    Fang J; McKay G; Song J; Remillrd A; Li X; Midha K
    Drug Metab Dispos; 2001 Dec; 29(12):1638-43. PubMed ID: 11717183
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxy-methamphetamine and its enantiomers.
    Meyer MR; Peters FT; Maurer HH
    Drug Metab Dispos; 2008 Nov; 36(11):2345-54. PubMed ID: 18725511
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.
    Hutchinson MR; Menelaou A; Foster DJ; Coller JK; Somogyi AA
    Br J Clin Pharmacol; 2004 Mar; 57(3):287-97. PubMed ID: 14998425
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The oxidative metabolism of dimemorfan by human cytochrome P450 enzymes.
    Chou YC; Chung YT; Liu TY; Wang SY; Chau GY; Chi CW; Soucek P; Krausz KW; Gelboin HV; Lee CH; Ueng YF
    J Pharm Sci; 2010 Feb; 99(2):1063-77. PubMed ID: 19593786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of recombinant cytochrome P450 enzymes as an in vitro system for metabolic clearance predictions.
    Stringer RA; Strain-Damerell C; Nicklin P; Houston JB
    Drug Metab Dispos; 2009 May; 37(5):1025-34. PubMed ID: 19196847
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.
    Subrahmanyam V; Renwick AB; Walters DG; Young PJ; Price RJ; Tonelli AP; Lake BG
    Drug Metab Dispos; 2001 Aug; 29(8):1146-55. PubMed ID: 11454734
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polymorphic hydroxylation of perhexiline in vitro.
    Sørensen LB; Sørensen RN; Miners JO; Somogyi AA; Grgurinovich N; Birkett DJ
    Br J Clin Pharmacol; 2003 Jun; 55(6):635-8. PubMed ID: 12814462
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study.
    Obach RS; Cox LM; Tremaine LM
    Drug Metab Dispos; 2005 Feb; 33(2):262-70. PubMed ID: 15547048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.