BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 17050796)

  • 1. Simultaneous measurement of in vivo P-glycoprotein and cytochrome P450 3A activities.
    Kirby B; Kharasch ED; Thummel KT; Narang VS; Hoffer CJ; Unadkat JD
    J Clin Pharmacol; 2006 Nov; 46(11):1313-9. PubMed ID: 17050796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
    Becquemont L; Glaeser H; Drescher S; Hitzl M; Simon N; Murdter TE; Heinkele G; Hofmann U; Schaefer C; Burk O; Verstuyft C; Eichelbaum M; Fromm MF
    Clin Pharmacol Ther; 2006 May; 79(5):449-60. PubMed ID: 16678547
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetic-Interactions of BI 425809, a Novel Glycine Transporter 1 Inhibitor, With Cytochrome P450 and P-Glycoprotein Substrates: Findings From In Vitro Analyses and an Open-Label, Single-Sequence Phase I Study.
    Desch M; Schlecker C; Hohl K; Liesenfeld KH; Chan T; Müller F; Wunderlich G; Keller S; Ishiguro N; Wind S
    J Clin Psychopharmacol; 2023 Mar-Apr 01; 43(2):113-121. PubMed ID: 36700734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Drug-Drug Interactions of the Nonsteroidal Mineralocorticoid Receptor Antagonist Apararenone With Midazolam, Warfarin, and Digoxin: A Phase 1 Studies in Healthy Volunteers.
    Nakamura T; Shimizu H; Kawaguchi A
    Clin Ther; 2020 Nov; 42(11):2171-2183.e4. PubMed ID: 33153727
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cisapride: a potential model substrate to assess cytochrome P4503A4 activity in vivo.
    Lowry JA; Kearns GL; Abdel-Rahman SM; Nafziger AN; Khan IS; Kashuba AD; Schuetz EG; Bertino JS; van den Anker JN; Leeder JS
    Clin Pharmacol Ther; 2003 Mar; 73(3):209-22. PubMed ID: 12621386
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of telaprevir on the pharmacokinetics of midazolam and digoxin.
    Garg V; Chandorkar G; Farmer HF; Smith F; Alves K; van Heeswijk RP
    J Clin Pharmacol; 2012 Oct; 52(10):1566-73. PubMed ID: 22162542
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Do activities of cytochrome P450 (CYP)3A, CYP2D6 and P-glycoprotein differ between healthy volunteers and HIV-infected patients?
    Jetter A; Fätkenheuer G; Frank D; Klaassen T; Seeringer A; Doroshyenko O; Kirchheiner J; Hein W; Schömig E; Fuhr U; Wyen C
    Antivir Ther; 2010; 15(7):975-83. PubMed ID: 21041912
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants.
    Malati CY; Robertson SM; Hunt JD; Chairez C; Alfaro RM; Kovacs JA; Penzak SR
    J Clin Pharmacol; 2012 Jun; 52(6):932-9. PubMed ID: 21646440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of fermented red ginseng on cytochrome P450 and P-glycoprotein activity in healthy subjects, as evaluated using the cocktail approach.
    Kim MG; Kim Y; Jeon JY; Kim DS
    Br J Clin Pharmacol; 2016 Dec; 82(6):1580-1590. PubMed ID: 27495955
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study.
    Hebert MF; Easterling TR; Kirby B; Carr DB; Buchanan ML; Rutherford T; Thummel KE; Fishbein DP; Unadkat JD
    Clin Pharmacol Ther; 2008 Aug; 84(2):248-53. PubMed ID: 18288078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens.
    Moj D; Hanke N; Britz H; Frechen S; Kanacher T; Wendl T; Haefeli WE; Lehr T
    AAPS J; 2017 Jan; 19(1):298-312. PubMed ID: 27822600
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects.
    Kakuda TN; Van Solingen-Ristea RM; Onkelinx J; Stevens T; Aharchi F; De Smedt G; Peeters M; Leopold L; Hoetelmans RM
    J Clin Pharmacol; 2014 Apr; 54(4):422-31. PubMed ID: 24165884
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytochrome P450 3A and P-glycoprotein drug-drug interactions with voclosporin.
    Ling SY; Huizinga RB; Mayo PR; Larouche R; Freitag DG; Aspeslet LJ; Foster RT
    Br J Clin Pharmacol; 2014 Jun; 77(6):1039-50. PubMed ID: 24330024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective inhibition of human cytochrome P450 3A4 by N-[2(R)-hydroxy-1(S)-indanyl]-5-[2(S)-(1, 1-dimethylethylaminocarbonyl)-4-[(furo[2, 3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethy lpentanamide and P-glycoprotein by valspodar in gene transfectant systems.
    Kawahara I; Kato Y; Suzuki H; Achira M; Ito K; Crespi CL; Sugiyama Y
    Drug Metab Dispos; 2000 Oct; 28(10):1238-43. PubMed ID: 10997946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of Potential Drug-Drug Interaction Risk of Pexidartinib With Substrates of Cytochrome P450 and P-Glycoprotein.
    Zahir H; Kobayashi F; Zamora C; Gajee R; Gordon MS; Babiker HM; Wang Q; Greenberg J; Wagner AJ
    J Clin Pharmacol; 2021 Mar; 61(3):298-306. PubMed ID: 32918831
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cinacalcet does not affect the activity of cytochrome P450 3A enzymes, a metabolic pathway for common immunosuppressive agents : a randomized, open-label, crossover, single-centre study in healthy volunteers.
    Padhi D; Salfi M; Emery M
    Drugs R D; 2008; 9(5):335-43. PubMed ID: 18721002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery.
    Chen KF; Chan LN; Lin YS
    J Pharmacokinet Pharmacodyn; 2020 Oct; 47(5):493-512. PubMed ID: 32710209
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects.
    Mueck W; Kubitza D; Becka M
    Br J Clin Pharmacol; 2013 Sep; 76(3):455-66. PubMed ID: 23305158
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simultaneously predict pharmacokinetic interaction of rifampicin with oral versus intravenous substrates of cytochrome P450 3A/P‑glycoprotein to healthy human using a semi-physiologically based pharmacokinetic model involving both enzyme and transporter turnover.
    Qian CQ; Zhao KJ; Chen Y; Liu L; Liu XD
    Eur J Pharm Sci; 2019 Jun; 134():194-204. PubMed ID: 31047967
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of felodipine as a potential perpetrator of pharmacokinetic drug-drug interactions.
    Snyder BD; Rowland A; Polasek TM; Miners JO; Doogue MP
    Eur J Clin Pharmacol; 2014 Sep; 70(9):1115-22. PubMed ID: 25028073
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.