These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection. Gardelli C; Attenni B; Donghi M; Meppen M; Pacini B; Harper S; Di Marco A; Fiore F; Giuliano C; Pucci V; Laufer R; Gennari N; Marcucci I; Leone JF; Olsen DB; MacCoss M; Rowley M; Narjes F J Med Chem; 2009 Sep; 52(17):5394-407. PubMed ID: 19725579 [TBL] [Abstract][Full Text] [Related]
7. Synthesis and antiviral activity of novel derivatives of 2'-beta-C-methylcytidine. Fogt J; Januszczyk P; Framski G; Onishi T; Izawa K; De Clercq E; Neyts J; Boryski J Nucleic Acids Symp Ser (Oxf); 2008; (52):605-6. PubMed ID: 18776525 [TBL] [Abstract][Full Text] [Related]
8. Cyclic phosphoramidates as prodrugs of 2'-C-methylcytidine. Meppen M; Pacini B; Bazzo R; Koch U; Leone JF; Koeplinger KA; Rowley M; Altamura S; Di Marco A; Fiore F; Giuliano C; Gonzalez-Paz O; Laufer R; Pucci V; Narjes F; Gardelli C Eur J Med Chem; 2009 Sep; 44(9):3765-70. PubMed ID: 19493593 [TBL] [Abstract][Full Text] [Related]
9. Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability. Brandl M; Wu X; Holper M; Hong L; Jia Z; Birudaraj R; Reddy M; Alfredson T; Tran T; Larrabee S; Hadig X; Sarma K; Washington C; Hill G; Smith DB Drug Dev Ind Pharm; 2008 Jul; 34(7):683-91. PubMed ID: 18612909 [TBL] [Abstract][Full Text] [Related]
10. Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication. Nilsson M; Kalayanov G; Winqvist A; Pinho P; Sund C; Zhou XX; Wähling H; Belfrage AK; Pelcman M; Agback T; Benckestock K; Wikström K; Boothee M; Lindqvist A; Rydegård C; Jonckers TH; Vandyck K; Raboisson P; Lin TI; Lachau-Durand S; de Kock H; Smith DB; Martin JA; Klumpp K; Simmen K; Vrang L; Terelius Y; Samuelsson B; Rosenquist S; Johansson NG Bioorg Med Chem Lett; 2012 May; 22(9):3265-8. PubMed ID: 22472694 [TBL] [Abstract][Full Text] [Related]
11. 2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase. Jonckers TH; Lin TI; Buyck C; Lachau-Durand S; Vandyck K; Van Hoof S; Vandekerckhove LA; Hu L; Berke JM; Vijgen L; Dillen LL; Cummings MD; de Kock H; Nilsson M; Sund C; Rydegård C; Samuelsson B; Rosenquist A; Fanning G; Van Emelen K; Simmen K; Raboisson P J Med Chem; 2010 Nov; 53(22):8150-60. PubMed ID: 21033671 [TBL] [Abstract][Full Text] [Related]
12. Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents. Pei X; Choi WJ; Kim YM; Zhao LX; Jeong LS Arch Pharm Res; 2008 Jul; 31(7):843-9. PubMed ID: 18704325 [TBL] [Abstract][Full Text] [Related]
13. Synthesis, physicochemical and pharmacokinetic studies of potential prodrugs of beta-L-2'-deoxycytidine, a selective and specific anti-HBV agent. Pierra C; Benzaria S; Dukhan D; Loi AG; La Colla P; Bridges E; Mao J; Standring D; Sommadossi JP; Gosselin G Antivir Chem Chemother; 2004 Sep; 15(5):269-79. PubMed ID: 15535049 [TBL] [Abstract][Full Text] [Related]
14. Evaluation of the role of three candidate human kinases in the conversion of the hepatitis C virus inhibitor 2'-C-methyl-cytidine to its 5'-monophosphate metabolite. Golitsina NL; Danehy FT; Fellows R; Cretton-Scott E; Standring DN Antiviral Res; 2010 Mar; 85(3):470-81. PubMed ID: 19883694 [TBL] [Abstract][Full Text] [Related]
15. Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents. McGuigan C; Madela K; Aljarah M; Bourdin C; Arrica M; Barrett E; Jones S; Kolykhalov A; Bleiman B; Bryant KD; Ganguly B; Gorovits E; Henson G; Hunley D; Hutchins J; Muhammad J; Obikhod A; Patti J; Walters CR; Wang J; Vernachio J; Ramamurty CV; Battina SK; Chamberlain S J Med Chem; 2011 Dec; 54(24):8632-45. PubMed ID: 22039920 [TBL] [Abstract][Full Text] [Related]
16. Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors. Cho A; Zhang L; Xu J; Babusis D; Butler T; Lee R; Saunders OL; Wang T; Parrish J; Perry J; Feng JY; Ray AS; Kim CU Bioorg Med Chem Lett; 2012 Jun; 22(12):4127-32. PubMed ID: 22578461 [TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of imidazole N-H substituted amide prodrugs as inhibitors of hepatitis C virus replication. Zong X; Cai J; Chen J; Wang P; Zhou G; Chen B; Li W; Ji M Bioorg Med Chem Lett; 2015 Aug; 25(16):3147-50. PubMed ID: 26077493 [TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication. Clark JL; Hollecker L; Mason JC; Stuyver LJ; Tharnish PM; Lostia S; McBrayer TR; Schinazi RF; Watanabe KA; Otto MJ; Furman PA; Stec WJ; Patterson SE; Pankiewicz KW J Med Chem; 2005 Aug; 48(17):5504-8. PubMed ID: 16107149 [TBL] [Abstract][Full Text] [Related]
19. Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides. Choi WJ; Kim YM; Kim HO; Lee HW; Kim DE; Park KS; Chong Y; Jeong LS Bioorg Med Chem; 2010 Jul; 18(13):4812-20. PubMed ID: 20627592 [TBL] [Abstract][Full Text] [Related]
20. Pharmacokinetics of the antiviral agent beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine in rhesus monkeys. Asif G; Hurwitz SJ; Shi J; Hernandez-Santiago BI; Schinazi RF Antimicrob Agents Chemother; 2007 Aug; 51(8):2877-82. PubMed ID: 17562805 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]