167 related articles for article (PubMed ID: 17065199)
1. Genistein protects human mammary epithelial cells from benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S-transferase system.
Steiner C; Peters WH; Gallagher EP; Magee P; Rowland I; Pool-Zobel BL
Carcinogenesis; 2007 Mar; 28(3):738-48. PubMed ID: 17065199
[TBL] [Abstract][Full Text] [Related]
2. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase.
Hu X; Herzog C; Zimniak P; Singh SV
Cancer Res; 1999 May; 59(10):2358-62. PubMed ID: 10344744
[TBL] [Abstract][Full Text] [Related]
3. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
Kushman ME; Kabler SL; Fleming MH; Ravoori S; Gupta RC; Doehmer J; Morrow CS; Townsend AJ
Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
[TBL] [Abstract][Full Text] [Related]
4. Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate.
Knoll N; Ruhe C; Veeriah S; Sauer J; Glei M; Gallagher EP; Pool-Zobel BL
Toxicol Sci; 2005 Jul; 86(1):27-35. PubMed ID: 15829614
[TBL] [Abstract][Full Text] [Related]
5. Overexpression of stably transfected human glutathione S-transferase P1-1 protects against DNA damage by benzo[a]pyrene diol-epoxide in human T47D cells.
Fields WR; Morrow CS; Doss AJ; Sundberg K; Jernström B; Townsend AJ
Mol Pharmacol; 1998 Aug; 54(2):298-304. PubMed ID: 9687571
[TBL] [Abstract][Full Text] [Related]
6. Chemoprotective functions of glutathione S-transferases in cell lines induced to express specific isozymes by stable transfection.
Townsend AJ; Fields WR; Haynes RL; Doss AJ; Li Y; Doehmer J; Morrow CS
Chem Biol Interact; 1998 Apr; 111-112():389-407. PubMed ID: 9679569
[TBL] [Abstract][Full Text] [Related]
7. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
Hu X; O'Donnell R; Srivastava SK; Xia H; Zimniak P; Nanduri B; Bleicher RJ; Awasthi S; Awasthi YC; Ji X; Singh SV
Biochem Biophys Res Commun; 1997 Jun; 235(2):424-8. PubMed ID: 9199210
[TBL] [Abstract][Full Text] [Related]
8. Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1.
Kushman ME; Kabler SL; Ahmad S; Doehmer J; Morrow CS; Townsend AJ
Toxicol Sci; 2007 Sep; 99(1):51-7. PubMed ID: 17525473
[TBL] [Abstract][Full Text] [Related]
9. Butyrate induces glutathione S-transferase in human colon cells and protects from genetic damage by 4-hydroxy-2-nonenal.
Ebert MN; Beyer-Sehlmeyer G; Liegibel UM; Kautenburger T; Becker TW; Pool-Zobel BL
Nutr Cancer; 2001; 41(1-2):156-64. PubMed ID: 12094619
[TBL] [Abstract][Full Text] [Related]
10. Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide.
Coles B; Yang M; Lang NP; Kadlubar FF
Cancer Lett; 2000 Aug; 156(2):167-75. PubMed ID: 10880766
[TBL] [Abstract][Full Text] [Related]
11. Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.
Kabler SL; Seidel A; Jacob J; Doehmer J; Morrow CS; Townsend AJ
Chem Biol Interact; 2009 May; 179(2-3):240-6. PubMed ID: 19330882
[TBL] [Abstract][Full Text] [Related]
12. Antineoplastic drug sensitivity of human MCF-7 breast cancer cells stably transfected with a human alpha class glutathione S-transferase gene.
Leyland-Jones BR; Townsend AJ; Tu CP; Cowan KH; Goldsmith ME
Cancer Res; 1991 Jan; 51(2):587-94. PubMed ID: 1985777
[TBL] [Abstract][Full Text] [Related]
13. Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress.
Raschke M; Rowland IR; Magee PJ; Pool-Zobel BL
Carcinogenesis; 2006 Nov; 27(11):2322-30. PubMed ID: 16774941
[TBL] [Abstract][Full Text] [Related]
14. Modeling the metabolic competency of glutathione S-transferases using genetically modified cell lines.
Townsend AJ; Kabler SL; Doehmer J; Morrow CS
Toxicology; 2002 Dec; 181-182():265-9. PubMed ID: 12505323
[TBL] [Abstract][Full Text] [Related]
15. The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN.
Dave B; Eason RR; Till SR; Geng Y; Velarde MC; Badger TM; Simmen RC
Carcinogenesis; 2005 Oct; 26(10):1793-803. PubMed ID: 15905199
[TBL] [Abstract][Full Text] [Related]
16. Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials.
Steinkellner H; Hoelzl C; Uhl M; Cavin C; Haidinger G; Gsur A; Schmid R; Kundi M; Bichler J; Knasmüller S
Mutat Res; 2005 Dec; 591(1-2):264-75. PubMed ID: 16099480
[TBL] [Abstract][Full Text] [Related]
17. Comparison of the mRNA sequences for Pi class glutathione transferases in different hamster species and the corresponding enzyme activities with anti-benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide.
Swedmark S; Jernström B; Jenssen D
Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):533-8. PubMed ID: 8809043
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression.
Ahmad S; Kabler SL; Rudd L; Amin S; Doehmer J; Morrow CS; Townsend AJ
Toxicol Lett; 2008 Dec; 183(1-3):99-104. PubMed ID: 18992797
[TBL] [Abstract][Full Text] [Related]
19. Role of glutathione conjugate efflux in cellular protection against benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage.
Srivastava SK; Watkins SC; Schuetz E; Singh SV
Mol Carcinog; 2002 Mar; 33(3):156-62. PubMed ID: 11870881
[TBL] [Abstract][Full Text] [Related]
20. Factors influencing elevation of intracellular Ca2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons.
Tannheimer SL; Lauer FT; Lane J; Burchiel SW
Mol Carcinog; 1999 May; 25(1):48-54. PubMed ID: 10331744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
