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4. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1. Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464 [TBL] [Abstract][Full Text] [Related]
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