BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 17070062)

  • 1. Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder.
    Pryde DC; Cook AS; Burring DJ; Jones LH; Foll S; Platts MY; Sanderson V; Corless M; Stobie A; Middleton DS; Foster L; Barker L; Van Der Graaf P; Stacey P; Kohl C; Coggon S; Beaumont K
    Bioorg Med Chem; 2007 Jan; 15(1):142-59. PubMed ID: 17070062
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramides.
    Pryde DC; Maw GN; Planken S; Platts MY; Sanderson V; Corless M; Stobie A; Barber CG; Russell R; Foster L; Barker L; Wayman C; Van Der Graaf P; Stacey P; Morren D; Kohl C; Beaumont K; Coggon S; Tute M
    J Med Chem; 2006 Jul; 49(14):4409-24. PubMed ID: 16821800
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The discovery of small molecule inhibitors of neutral endopeptidase. Structure-activity studies on functionalized glutaramides.
    Maw GN; Stobie A; Planken S; Pryde DC; Sanderson V; Platts MY; Corless M; Stacey P; Wayman C; Van Der Graaf P; Kohl C; Coggon S; Beaumont K
    Chem Biol Drug Des; 2006 Jan; 67(1):74-7. PubMed ID: 16492151
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors.
    Glossop MS; Bazin RJ; Dack KN; Fox DN; MacDonald GA; Mills M; Owen DR; Phillips C; Reeves KA; Ringer TJ; Strang RS; Watson CA
    Bioorg Med Chem Lett; 2011 Jun; 21(11):3404-6. PubMed ID: 21515054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vascular neutral endopeptidase inhibition improves endothelial function and reduces intimal hyperplasia.
    Barber MN; Kanagasundaram M; Anderson CR; Burrell LM; Woods RL
    Cardiovasc Res; 2006 Jul; 71(1):179-88. PubMed ID: 16635483
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.
    Olimpieri F; Tambaro S; Fustero S; Lazzari P; Sanchez-Roselló M; Pani L; Volonterio A; Zanda M
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4715-9. PubMed ID: 19596577
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel and potent VLA-4 antagonist based on trans-4-substituted cyclohexanecarboxylic acid.
    Muro F; Iimura S; Yoneda Y; Chiba J; Watanabe T; Setoguchi M; Takayama G; Yokoyama M; Takashi T; Nakayama A; Machinaga N
    Bioorg Med Chem; 2009 Feb; 17(3):1232-43. PubMed ID: 19124247
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A labeled neutral endopeptidase inhibitor as a potential tool for tumor diagnosis and prognosis.
    Raguin O; Fournié-Zaluski MC; Romieu A; Pèlegrin A; Chatelet F; Pélaprat D; Barbet J; Roques BP; Gruaz-Guyon A
    Angew Chem Int Ed Engl; 2005 Jun; 44(26):4058-61. PubMed ID: 15926197
    [No Abstract]   [Full Text] [Related]  

  • 9. Neutral endopeptidase inhibition: could it have a role in the treatment of female sexual arousal disorder?
    Angulo J
    Br J Pharmacol; 2010 May; 160(1):48-50. PubMed ID: 20412067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and SAR of succinamide peptidomimetic inhibitors of cathepsin S.
    Chatterjee AK; Liu H; Tully DC; Guo J; Epple R; Russo R; Williams J; Roberts M; Tuntland T; Chang J; Gordon P; Hollenbeck T; Tumanut C; Li J; Harris JL
    Bioorg Med Chem Lett; 2007 May; 17(10):2899-903. PubMed ID: 17382545
    [TBL] [Abstract][Full Text] [Related]  

  • 11. (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.
    Wright SW; Ammirati MJ; Andrews KM; Brodeur AM; Danley DE; Doran SD; Lillquist JS; Liu S; McClure LD; McPherson RK; Olson TV; Orena SJ; Parker JC; Rocke BN; Soeller WC; Soglia CB; Treadway JL; Vanvolkenburg MA; Zhao Z; Cox ED
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5638-42. PubMed ID: 17822893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The discovery and synthesis of potent zwitterionic inhibitors of renin.
    Aspiotis R; Chen A; Cauchon E; Dubé D; Falgueyret JP; Gagné S; Gallant M; Grimm EL; Houle R; Juteau H; Lacombe P; Laliberté S; Lévesque JF; MacDonald D; McKay D; Percival MD; Roy P; Soisson SM; Wu T
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2430-6. PubMed ID: 21429746
    [TBL] [Abstract][Full Text] [Related]  

  • 13. From lead to preclinical candidate: optimization of beta-homophenylalanine based inhibitors of dipeptidyl peptidase IV.
    Nordhoff S; López-Canet M; Hoffmann-Enger B; Bulat S; Cerezo-Gálvez S; Hill O; Rosenbaum C; Rummey C; Thiemann M; Matassa VG; Edwards PJ; Feurer A
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4818-23. PubMed ID: 19576767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, SAR, and X-ray structure of novel potent DPPIV inhibitors: oxadiazolyl ketones.
    Koo KD; Kim MJ; Kim S; Kim KH; Hong SY; Hur GC; Yim HJ; Kim GT; Han HO; Kwon OH; Kwon TS; Koh JS; Lee CS
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4167-72. PubMed ID: 17544668
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Formation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril.
    Kaye B; Brearley CJ; Cussans NJ; Herron M; Humphrey MJ; Mollatt AR
    Xenobiotica; 1997 Oct; 27(10):1091-102. PubMed ID: 9364744
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors.
    Tully DC; Liu H; Chatterjee AK; Alper PB; Williams JA; Roberts MJ; Mutnick D; Woodmansee DH; Hollenbeck T; Gordon P; Chang J; Tuntland T; Tumanut C; Li J; Harris JL; Karanewsky DS
    Bioorg Med Chem Lett; 2006 Oct; 16(19):5107-11. PubMed ID: 16876407
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitors.
    Corbett JW; Dirico K; Song W; Boscoe BP; Doran SD; Boyer D; Qiu X; Ammirati M; Vanvolkenburg MA; McPherson RK; Parker JC; Cox ED
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6707-13. PubMed ID: 17977724
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Second generation of BACE-1 inhibitors part 3: Towards non hydroxyethylamine transition state mimetics.
    Charrier N; Clarke B; Cutler L; Demont E; Dingwall C; Dunsdon R; Hawkins J; Howes C; Hubbard J; Hussain I; Maile G; Matico R; Mosley J; Naylor A; O'Brien A; Redshaw S; Rowland P; Soleil V; Smith KJ; Sweitzer S; Theobald P; Vesey D; Walter DS; Wayne G
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3674-8. PubMed ID: 19406640
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel series of highly selective inhibitors of MMP-3.
    Whitlock GA; Dack KN; Dickinson RP; Lewis ML
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6750-3. PubMed ID: 18029177
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of long-acting inhibitors of dipeptidyl peptidase IV.
    Kondo T; Sugimoto I; Nekado T; Ochi K; Ohtani T; Tajima Y; Yamamoto S; Kawabata K; Nakai H; Toda M
    Bioorg Med Chem; 2007 Apr; 15(7):2715-35. PubMed ID: 17292611
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.