These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 17073441)

  • 1. Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cdelta, Wip1.
    Yamaguchi H; Durell SR; Feng H; Bai Y; Anderson CW; Appella E
    Biochemistry; 2006 Nov; 45(44):13193-202. PubMed ID: 17073441
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrate specificity of the human protein phosphatase 2Cdelta, Wip1.
    Yamaguchi H; Minopoli G; Demidov ON; Chatterjee DK; Anderson CW; Durell SR; Appella E
    Biochemistry; 2005 Apr; 44(14):5285-94. PubMed ID: 15807522
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.
    Yamaguchi H; Durell SR; Chatterjee DK; Anderson CW; Appella E
    Biochemistry; 2007 Nov; 46(44):12594-603. PubMed ID: 17939684
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1).
    Hayashi R; Tanoue K; Durell SR; Chatterjee DK; Jenkins LM; Appella DH; Appella E
    Biochemistry; 2011 May; 50(21):4537-49. PubMed ID: 21528848
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of the active site and a unique uncompetitive inhibitor of the PPM1-type protein phosphatase PPM1D.
    Chuman Y; Yagi H; Fukuda T; Nomura T; Matsukizono M; Shimohigashi Y; Sakaguchi K
    Protein Pept Lett; 2008; 15(9):938-48. PubMed ID: 18991770
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding of a third metal ion by the human phosphatases PP2Cα and Wip1 is required for phosphatase activity.
    Tanoue K; Miller Jenkins LM; Durell SR; Debnath S; Sakai H; Tagad HD; Ishida K; Appella E; Mazur SJ
    Biochemistry; 2013 Aug; 52(34):5830-43. PubMed ID: 23906386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing protein phosphatase substrate binding: affinity pull-down of ILKAP phosphatase 2C with phosphopeptides.
    Højlys-Larsen KB; Sørensen KK; Jensen KJ; Gammeltoft S
    Mol Biosyst; 2012 Apr; 8(5):1452-60. PubMed ID: 22348942
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction.
    Gilmartin AG; Faitg TH; Richter M; Groy A; Seefeld MA; Darcy MG; Peng X; Federowicz K; Yang J; Zhang SY; Minthorn E; Jaworski JP; Schaber M; Martens S; McNulty DE; Sinnamon RH; Zhang H; Kirkpatrick RB; Nevins N; Cui G; Pietrak B; Diaz E; Jones A; Brandt M; Schwartz B; Heerding DA; Kumar R
    Nat Chem Biol; 2014 Mar; 10(3):181-7. PubMed ID: 24390428
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.
    Lu X; Nguyen TA; Moon SH; Darlington Y; Sommer M; Donehower LA
    Cancer Metastasis Rev; 2008 Jun; 27(2):123-35. PubMed ID: 18265945
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A.
    Donella Deana A; Mac Gowan CH; Cohen P; Marchiori F; Meyer HE; Pinna LA
    Biochim Biophys Acta; 1990 Feb; 1051(2):199-202. PubMed ID: 2155667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.
    Yoda A; Xu XZ; Onishi N; Toyoshima K; Fujimoto H; Kato N; Oishi I; Kondo T; Minami Y
    J Biol Chem; 2006 Aug; 281(34):24847-62. PubMed ID: 16798742
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PP2Cdelta (Ppm1d, WIP1), an endogenous inhibitor of p38 MAPK, is regulated along with Trp53 and Cdkn2a following p38 MAPK inhibition during mouse preimplantation development.
    Hickson JA; Fong B; Watson PH; Watson AJ
    Mol Reprod Dev; 2007 Jul; 74(7):821-34. PubMed ID: 17219434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor.
    Endo S; Zhou X; Connor J; Wang B; Shenolikar S
    Biochemistry; 1996 Apr; 35(16):5220-8. PubMed ID: 8611507
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma.
    Fuku T; Semba S; Yutori H; Yokozaki H
    Pathol Int; 2007 Sep; 57(9):566-71. PubMed ID: 17685927
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
    Yu E; Ahn YS; Jang SJ; Kim MJ; Yoon HS; Gong G; Choi J
    Breast Cancer Res Treat; 2007 Mar; 101(3):269-78. PubMed ID: 16897432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WIP1 phosphatase at the crossroads of cancer and aging.
    Le Guezennec X; Bulavin DV
    Trends Biochem Sci; 2010 Feb; 35(2):109-14. PubMed ID: 19879149
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
    Debnath S; Kosek D; Tagad HD; Durell SR; Appella DH; Acevedo R; Grishaev A; Dyda F; Appella E; Mazur SJ
    J Biol Chem; 2018 May; 293(21):7993-8008. PubMed ID: 29602904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical characterization and deletion analysis of recombinant human protein phosphatase 2C alpha.
    Marley AE; Sullivan JE; Carling D; Abbott WM; Smith GJ; Taylor IW; Carey F; Beri RK
    Biochem J; 1996 Dec; 320 ( Pt 3)(Pt 3):801-6. PubMed ID: 9003365
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPM1D regulates p21 expression via dephoshporylation at serine 123.
    Cao R; Zhang J; Zhang M; Chen X
    Cell Cycle; 2015; 14(4):641-7. PubMed ID: 25590690
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Determinants for substrate specificity of the bacterial PP2C protein phosphatase tPphA from Thermosynechococcus elongatus.
    Su J; Forchhammer K
    FEBS J; 2013 Jan; 280(2):694-707. PubMed ID: 22212593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.