161 related articles for article (PubMed ID: 17073780)
1. CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.
McLean KJ; Dunford AJ; Sabri M; Neeli R; Girvan HM; Balding PR; Leys D; Seward HE; Marshall KR; Munro AW
Biochem Soc Trans; 2006 Dec; 34(Pt 6):1178-82. PubMed ID: 17073780
[TBL] [Abstract][Full Text] [Related]
2. Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes.
McLean KJ; Marshall KR; Richmond A; Hunter IS; Fowler K; Kieser T; Gurcha SS; Besra GS; Munro AW
Microbiology (Reading); 2002 Oct; 148(Pt 10):2937-2949. PubMed ID: 12368427
[TBL] [Abstract][Full Text] [Related]
3. Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions.
McLean KJ; Warman AJ; Seward HE; Marshall KR; Girvan HM; Cheesman MR; Waterman MR; Munro AW
Biochemistry; 2006 Jul; 45(27):8427-43. PubMed ID: 16819841
[TBL] [Abstract][Full Text] [Related]
4. The preponderance of P450s in the Mycobacterium tuberculosis genome.
McLean KJ; Clift D; Lewis DG; Sabri M; Balding PR; Sutcliffe MJ; Leys D; Munro AW
Trends Microbiol; 2006 May; 14(5):220-8. PubMed ID: 16581251
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode.
Seward HE; Roujeinikova A; McLean KJ; Munro AW; Leys D
J Biol Chem; 2006 Dec; 281(51):39437-43. PubMed ID: 17028183
[TBL] [Abstract][Full Text] [Related]
6. Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
McLean KJ; Carroll P; Lewis DG; Dunford AJ; Seward HE; Neeli R; Cheesman MR; Marsollier L; Douglas P; Smith WE; Rosenkrands I; Cole ST; Leys D; Parish T; Munro AW
J Biol Chem; 2008 Nov; 283(48):33406-16. PubMed ID: 18818197
[TBL] [Abstract][Full Text] [Related]
7. Expression and characterization of Mycobacterium tuberculosis CYP144: common themes and lessons learned in the M. tuberculosis P450 enzyme family.
Driscoll MD; McLean KJ; Cheesman MR; Jowitt TA; Howard M; Carroll P; Parish T; Munro AW
Biochim Biophys Acta; 2011 Jan; 1814(1):76-87. PubMed ID: 20621636
[TBL] [Abstract][Full Text] [Related]
8. Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis.
Munro AW; McLean KJ; Marshall KR; Warman AJ; Lewis G; Roitel O; Sutcliffe MJ; Kemp CA; Modi S; Scrutton NS; Leys D
Biochem Soc Trans; 2003 Jun; 31(Pt 3):625-30. PubMed ID: 12773169
[TBL] [Abstract][Full Text] [Related]
9. The Mycobacterium tuberculosis cytochromes P450: physiology, biochemistry & molecular intervention.
McLean KJ; Belcher J; Driscoll MD; Fernandez CC; Le Van D; Bui S; Golovanova M; Munro AW
Future Med Chem; 2010 Aug; 2(8):1339-53. PubMed ID: 21426022
[TBL] [Abstract][Full Text] [Related]
10. Rapid P450 heme iron reduction by laser photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1. Analysis of CO complexation reactions and reversibility of the P450/P420 equilibrium.
Dunford AJ; McLean KJ; Sabri M; Seward HE; Heyes DJ; Scrutton NS; Munro AW
J Biol Chem; 2007 Aug; 282(34):24816-24. PubMed ID: 17553785
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors.
Podust LM; Poulos TL; Waterman MR
Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3068-73. PubMed ID: 11248033
[TBL] [Abstract][Full Text] [Related]
12. Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems.
McLean KJ; Dunford AJ; Neeli R; Driscoll MD; Munro AW
Arch Biochem Biophys; 2007 Aug; 464(2):228-40. PubMed ID: 17482138
[TBL] [Abstract][Full Text] [Related]
13. Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 from
Dornevil K; Davis I; Fielding AJ; Terrell JR; Ma L; Liu A
J Biol Chem; 2017 Aug; 292(33):13645-13657. PubMed ID: 28667013
[TBL] [Abstract][Full Text] [Related]
14. Biodiversity of cytochrome P450 redox systems.
McLean KJ; Sabri M; Marshall KR; Lawson RJ; Lewis DG; Clift D; Balding PR; Dunford AJ; Warman AJ; McVey JP; Quinn AM; Sutcliffe MJ; Scrutton NS; Munro AW
Biochem Soc Trans; 2005 Aug; 33(Pt 4):796-801. PubMed ID: 16042601
[TBL] [Abstract][Full Text] [Related]
15. Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis.
Bellamine A; Mangla AT; Nes WD; Waterman MR
Proc Natl Acad Sci U S A; 1999 Aug; 96(16):8937-42. PubMed ID: 10430874
[TBL] [Abstract][Full Text] [Related]
16. Mycobacterium tuberculosis CYP130: crystal structure, biophysical characterization, and interactions with antifungal azole drugs.
Ouellet H; Podust LM; de Montellano PR
J Biol Chem; 2008 Feb; 283(8):5069-80. PubMed ID: 18089574
[TBL] [Abstract][Full Text] [Related]
17. Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis.
Matsuura K; Yoshioka S; Tosha T; Hori H; Ishimori K; Kitagawa T; Morishima I; Kagawa N; Waterman MR
J Biol Chem; 2005 Mar; 280(10):9088-96. PubMed ID: 15611056
[TBL] [Abstract][Full Text] [Related]
18. Structural biology and biochemistry of cytochrome P450 systems in Mycobacterium tuberculosis.
McLean KJ; Munro AW
Drug Metab Rev; 2008; 40(3):427-46. PubMed ID: 18642141
[TBL] [Abstract][Full Text] [Related]
19. Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs.
Lepesheva GI; Podust LM; Bellamine A; Waterman MR
J Biol Chem; 2001 Jul; 276(30):28413-20. PubMed ID: 11373285
[TBL] [Abstract][Full Text] [Related]
20. Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis: implications for treatment of tuberculosis.
Guardiola-Diaz HM; Foster LA; Mushrush D; Vaz AD
Biochem Pharmacol; 2001 Jun; 61(12):1463-70. PubMed ID: 11377375
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
