These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
170 related articles for article (PubMed ID: 17077484)
21. Molecular Determinants of N-Acetylglucosamine Recognition and Turnover by N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside Deacetylase (MshB). Huang X; Hernick M Biochemistry; 2015 Jun; 54(24):3784-90. PubMed ID: 26024468 [TBL] [Abstract][Full Text] [Related]
22. The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase. Young K; Silver LL; Bramhill D; Cameron P; Eveland SS; Raetz CR; Hyland SA; Anderson MS J Biol Chem; 1995 Dec; 270(51):30384-91. PubMed ID: 8530464 [TBL] [Abstract][Full Text] [Related]
23. A fluorescence-based homogeneous assay for measuring activity of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase. Wang W; Maniar M; Jain R; Jacobs J; Trias J; Yuan Z Anal Biochem; 2001 Mar; 290(2):338-46. PubMed ID: 11237337 [TBL] [Abstract][Full Text] [Related]
24. Overexpression of Pseudomonas aeruginosa LpxC with its inhibitors in an acrB-deficient Escherichia coli strain. Gao N; McLeod SM; Hajec L; Olivier NB; Lahiri SD; Bryan Prince D; Thresher J; Ross PL; Whiteaker JD; Doig P; Li AH; Hill PJ; Cornebise M; Reck F; Hale MR Protein Expr Purif; 2014 Dec; 104():57-64. PubMed ID: 25240855 [TBL] [Abstract][Full Text] [Related]
25. Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor. Mochalkin I; Knafels JD; Lightle S Protein Sci; 2008 Mar; 17(3):450-7. PubMed ID: 18287278 [TBL] [Abstract][Full Text] [Related]
26. Structure of the bacterial deacetylase LpxC bound to the nucleotide reaction product reveals mechanisms of oxyanion stabilization and proton transfer. Clayton GM; Klein DJ; Rickert KW; Patel SB; Kornienko M; Zugay-Murphy J; Reid JC; Tummala S; Sharma S; Singh SB; Miesel L; Lumb KJ; Soisson SM J Biol Chem; 2013 Nov; 288(47):34073-34080. PubMed ID: 24108127 [TBL] [Abstract][Full Text] [Related]
27. Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis. Barb AW; Zhou P Curr Pharm Biotechnol; 2008 Feb; 9(1):9-15. PubMed ID: 18289052 [TBL] [Abstract][Full Text] [Related]
28. Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC. Shin H; Gennadios HA; Whittington DA; Christianson DW Bioorg Med Chem; 2007 Apr; 15(7):2617-23. PubMed ID: 17296300 [TBL] [Abstract][Full Text] [Related]
29. Subtractive Genomics, Molecular Docking and Molecular Dynamics Simulation Revealed LpxC as a Potential Drug Target Against Multi-Drug Resistant Klebsiella pneumoniae. Ahmad S; Navid A; Akhtar AS; Azam SS; Wadood A; Pérez-Sánchez H Interdiscip Sci; 2019 Sep; 11(3):508-526. PubMed ID: 29721784 [TBL] [Abstract][Full Text] [Related]
30. Active site metal ion in UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) switches between Fe(II) and Zn(II) depending on cellular conditions. Gattis SG; Hernick M; Fierke CA J Biol Chem; 2010 Oct; 285(44):33788-96. PubMed ID: 20709752 [TBL] [Abstract][Full Text] [Related]
31. Insights into the Zinc-Dependent Deacetylase LpxC: Biochemical Properties and Inhibitor Design. Kalinin DV; Holl R Curr Top Med Chem; 2016; 16(21):2379-430. PubMed ID: 27072691 [TBL] [Abstract][Full Text] [Related]
32. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) inhibitors: a new class of antibacterial agents. Zhang J; Zhang L; Li X; Xu W Curr Med Chem; 2012; 19(13):2038-50. PubMed ID: 22414079 [TBL] [Abstract][Full Text] [Related]
33. Cloning, expression, and purification of UDP-3-O-acyl-GlcNAc deacetylase from Pseudomonas aeruginosa: a metalloamidase of the lipid A biosynthesis pathway. Hyland SA; Eveland SS; Anderson MS J Bacteriol; 1997 Mar; 179(6):2029-37. PubMed ID: 9068651 [TBL] [Abstract][Full Text] [Related]
34. LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis. Deli A; Koutsioulis D; Fadouloglou VE; Spiliotopoulou P; Balomenou S; Arnaouteli S; Tzanodaskalaki M; Mavromatis K; Kokkinidis M; Bouriotis V FEBS J; 2010 Jul; 277(13):2740-53. PubMed ID: 20491912 [TBL] [Abstract][Full Text] [Related]
35. Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding. Barb AW; Jiang L; Raetz CR; Zhou P Proc Natl Acad Sci U S A; 2007 Nov; 104(47):18433-8. PubMed ID: 18025458 [TBL] [Abstract][Full Text] [Related]
36. Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism. Nocek B; Reidl C; Starus A; Heath T; Bienvenue D; Osipiuk J; Jedrzejczak R; Joachimiak A; Becker DP; Holz RC Biochemistry; 2018 Feb; 57(5):574-584. PubMed ID: 29272107 [TBL] [Abstract][Full Text] [Related]
37. The inhibitory and binding studies of methyl-sulfone hydroxamate based inhibitors against LpxC from drug resistant Moraxella catarrhalis using biophysical, biochemical and in silico approaches. Sharma A; Kumar V; Pratap S; Kumar P Int J Biol Macromol; 2018 Oct; 118(Pt B):1747-1762. PubMed ID: 30017978 [TBL] [Abstract][Full Text] [Related]
38. Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA. Robins LI; Williams AH; Raetz CR Biochemistry; 2009 Jul; 48(26):6191-201. PubMed ID: 19456129 [TBL] [Abstract][Full Text] [Related]
39. Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa. Mdluli KE; Witte PR; Kline T; Barb AW; Erwin AL; Mansfield BE; McClerren AL; Pirrung MC; Tumey LN; Warrener P; Raetz CR; Stover CK Antimicrob Agents Chemother; 2006 Jun; 50(6):2178-84. PubMed ID: 16723580 [TBL] [Abstract][Full Text] [Related]
40. A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin. McClerren AL; Endsley S; Bowman JL; Andersen NH; Guan Z; Rudolph J; Raetz CR Biochemistry; 2005 Dec; 44(50):16574-83. PubMed ID: 16342948 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]